Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mami Kochi"'
Autor:
Shingo Tojo, Zhikuan Zhang, Hiroyuki Matsui, Masahiro Tahara, Mitsunori Ikeguchi, Mami Kochi, Mami Kamada, Hideki Shigematsu, Akihisa Tsutsumi, Naruhiko Adachi, Takuma Shibata, Masaki Yamamoto, Masahide Kikkawa, Toshiya Senda, Yoshiaki Isobe, Umeharu Ohto, Toshiyuki Shimizu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
A series of Toll-like receptor 7 (TLR7)-specific antagonists and extensive structural analysis reveal the open conformation of the receptor and the structural basis of TLR7 antagonism. One of the compounds shows efficacy in treating mouse model of sy
Externí odkaz:
https://doaj.org/article/be81925ea7f144b39dd225d5ffceb7a8
Autor:
Keigo Ikeda1 keigo1.ikeda@sumitomo-pharma.co.jp, Mami Kochi1, Tomoaki Tochitani1, Naohisa Umeya1, Izumi Matsumoto1, Yuta Fujii1, Toru Usui1, Izuru Miyawaki1
Publikováno v:
Fundamental Toxicological Sciences. 2024, Vol. 11 Issue 2, p69-78. 10p.
Autor:
Masahide Kikkawa, Mitsunori Ikeguchi, Masaki Yamamoto, Umeharu Ohto, Toshiyuki Shimizu, Akihisa Tsutsumi, Toshiya Senda, Shingo Tojo, Yoshiaki Isobe, Mami Kamada, Hideki Shigematsu, Mami Kochi, Takuma Shibata, Z. Zhang, Hiroyuki Matsui, Naruhiko Adachi, Masahiro Tahara
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Toll-like receptor 7 (TLR7) recognizes both microbial and endogenous RNAs and nucleosides. Aberrant activation of TLR7 has been implicated in several autoimmune diseases including systemic lupus erythematosus (SLE). Here, by modifying potent TLR7 ago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c459518c31964251e11aa45e111f262
https://doaj.org/article/be81925ea7f144b39dd225d5ffceb7a8
https://doaj.org/article/be81925ea7f144b39dd225d5ffceb7a8
Publikováno v:
Mechanical Engineering Journal, Vol 11, Iss 2, Pp 23-00386-23-00386 (2024)
Activation cross-section libraries for the ORIGEN and ORIGEN-S codes have been generated from the latest Japanese nuclear data library JENDL-5 and JENDL Activation Cross Section File for Nuclear Decommissioning 2017 (JENDL/AD-2017) for activation cal
Externí odkaz:
https://doaj.org/article/0ec6b449c951447dbed96056a760335e