Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mamen Regalado-Reyes"'
Autor:
Javier DeFelipe, Félix Hernández, Diana Furcila, Mamen Regalado-Reyes, Jesús Avila, Gonzalo León-Espinosa
Publikováno v:
Journal of Alzheimer's Disease
Digital.CSIC. Repositorio Institucional del CSIC
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Digital.CSIC. Repositorio Institucional del CSIC
instname
Despite extensive studies regarding tau phosphorylation progression in both human Alzheimer's disease cases and animal models, the molecular and structural changes responsible for neurofibrillary tangle development are still not well understood. Here
Autor:
Mamen Regalado-Reyes, Javier DeFelipe, Gonzalo León-Espinosa, Isabel Fernaud-Espinosa, Ruth Benavides-Piccione
Publikováno v:
Cerebral Cortex Communications
The dendritic spines of pyramidal cells are the main postsynaptic target of excitatory glutamatergic synapses. Morphological alterations have been described in hippocampal dendritic spines during hibernation—a state of inactivity and metabolic depr
Autor:
Gonzalo León-Espinosa, Javier DeFelipe, Asta Kastanauskaite, Ricardo Insausti, Ruth Benavides-Piccione, Idan Segev, Concepción Rojo, Isabel Fernaud-Espinosa, Silvia Tapia-González, Mamen Regalado-Reyes
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Cerebral Cortex
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Cerebral Cortex
Pyramidal neurons are the most common cell type and are considered the main output neuron in most mammalian forebrain structures. In terms of function, differences in the structure of the dendrites of these neurons appear to be crucial in determining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e18e1d2aaf20855e0fa14dc34d6d8a0
http://hdl.handle.net/10261/217458
http://hdl.handle.net/10261/217458
Autor:
Coral Barbas, Javier DeFelipe, Antonia García, Mamen Regalado-Reyes, Carolina Gonzalez-Riano, Gonzalo León-Espinosa
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Syrian hamsters undergo a reversible hyperphosphorylation of protein t during hibernation, providing a unique natural model that may unveil the physiological mechanisms behind this critical process involved in the development of Alzheimer's disease a
Publikováno v:
Brain structurefunction. 223(4)
Mammalian hibernation proceeds alongside a wide range of complex brain adaptive changes that appear to protect the brain from extreme hypoxia and hypothermia. Using immunofluorescence, confocal microscopy, quantitative analysis methods and intracellu