Zobrazeno 1 - 10 of 53 pro vyhledávání: '"Mamdouh Afify"'
1
Akademický článek
Intra-iliac bone marrow injection as a novel alternative to intra-tibial inoculation in rat model
Autor: Marwa S. Khattab, Huda O. AbuBakr, Kassem G. El Iraqi, Naglaa A. AbdElKader, Mervat M. Kamel, Khaled Hamed Salem, Julia Steitz, Mamdouh Afify
Publikováno v: Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background Intra-bone marrow injection (IBMI) in rats is adopted in many studies for stem cell and hematopoietic cell transplantation. IBMI in the tibia or the femur results in severe distress to the animal. Therefore, this study aims to eva
Externí odkaz: https://doaj.org/article/521a6ad7ee1e43eba9fe72461b268b89
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2
Akademický článek
Effects of asparaginases and L-carnitine on Western-diet-induced hepatosteatosis in mice [version 1; peer review: 1 approved, 2 approved with reservations]
Autor: Julia Steitz, Mamdouh Afify, Rene Tolba, Albrecht Eisert, Martina Hüffel, Mona Ali Mahmoud Assar, Ralf Weiskirchen
Publikováno v: F1000Research, Vol 11 (2022)
Abstract Background: Asparaginases are common chemotherapeutic agents used for the treatment of acute lymphoblastic leukemia as a single or combinational therapy. Accompanying hepatotoxicity makes its use in elderly patients with pre-conditions, as o
Externí odkaz: https://doaj.org/article/ad046f6f22ae4533b654242c39a43ee2
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3
Akademický článek
The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice
Autor: Theresa Streidl, Isabel Karkossa, Rafael R. Segura Muñoz, Claudia Eberl, Alex Zaufel, Johannes Plagge, Robert Schmaltz, Kristin Schubert, Marijana Basic, Kai Markus Schneider, Mamdouh Afify, Christian Trautwein, René Tolba, Bärbel Stecher, Heidi L. Doden, Jason M. Ridlon, Josef Ecker, Tarek Moustafa, Martin von Bergen, Amanda E. Ramer-Tait, Thomas Clavel
Publikováno v: Gut Microbes, Vol 13, Iss 1 (2021)
Extibacter muris is a newly described mouse gut bacterium which metabolizes cholic acid (CA) to deoxycholic acid (DCA) via 7α-dehydroxylation. Although bile acids influence metabolic and inflammatory responses, few in vivo models exist for studying
Externí odkaz: https://doaj.org/article/6ec78821605e4affb027a33487603e52
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4
Akademický článek
The Benefits of Fibrinolysis Combined with Venous Systemic Oxygen Persufflation (VSOP) in a Rat Model of Donation after Circulatory Death and Orthotopic Liver Transplantation
Autor: Nadja Kröger, Zoltan Czigany, Jipin Jiang, Mamdouh Afify, Pascal Paschenda, Kazuyuki Nagai, Shintaro Yagi, René H. Tolba
Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 9, p 5272 (2022)
Organ shortage has led to the increasing utilization of livers retrieved from donors after circulatory death (DCD). These pre-damaged organs are susceptible to further warm ischemia and exhibit minimal tolerance for cold storage. The aim was thus to
Externí odkaz: https://doaj.org/article/b96af6c13441485cbfb2f6883a516e9d
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5
Akademický článek
Sheep models for evaluation of novel patch and prosthesis material in vascular surgery: tips and tricks to avoid possible pitfalls
Autor: Karina Schleimer, Houman Jalaie, Mamdouh Afify, Anna Woitok, Mohammad Esmaeil Barbati, Konrad Hoeft, Michael Jacobs, Rene H. Tolba, Julia Steitz
Publikováno v: Acta Veterinaria Scandinavica, Vol 60, Iss 1, Pp 1-12 (2018)
Abstract Background In vascular surgery, novel synthetic prosthesis materials for patch-angioplasties, interpositions, bypasses and shunts are continuously under development and optimization. The characteristics of an ideal vascular prosthesis would
Externí odkaz: https://doaj.org/article/fe4137e322694c4480e9f06a01553f92
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6
Akademický článek
Apolipoprotein E4 Is Associated with Right Ventricular Dysfunction in Dilated Cardiomyopathy—An Animal and In-Human Comparative Study
Autor: Rodica Diaconu, Nicole Schaaps, Mamdouh Afify, Peter Boor, Anne Cornelissen, Roberta A. Florescu, Sakine Simsekyilmaz, Teddy El-Khoury, David Schumacher, Mihai Ioana, Ioana Streata, Constantin Militaru, Ionut Donoiu, Felix Vogt, Elisa A. Liehn
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 18, p 9688 (2021)
ApoE abnormality represents a well-known risk factor for cardiovascular diseases. Beyond its role in lipid metabolism, novel studies demonstrate a complex involvement of apoE in membrane homeostasis and signaling as well as in nuclear transcription.
Externí odkaz: https://doaj.org/article/a864240947514f728b7a5ddfc1677452
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7
Akademický článek
The Impact of a Nitric Oxide Synthase Inhibitor (L-NAME) on Ischemia–Reperfusion Injury of Cholestatic Livers by Pringle Maneuver and Liver Resection after Bile Duct Ligation in Rats
Autor: Junji Iwasaki, Mamdouh Afify, Christian Bleilevens, Uwe Klinge, Ralf Weiskirchen, Julia Steitz, Michael Vogt, Shintaro Yagi, Kazuyuki Nagai, Shinji Uemoto, Rene H. Tolba
Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 9, p 2114 (2019)
The Pringle maneuver (PM) has been widely used to control blood loss during liver resection. However, hepatic inflow occlusion can also result in hepatic ischemia−reperfusion injury (IRI), especially in patients with a cholestatic, fibrotic, or cir
Externí odkaz: https://doaj.org/article/d5e0981c55294f04951bf827a815bbd0
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9
Effect of Stent Strut Interval on Neointima Formation After Venous Stenting in an Ovine Model
Autor: Karina Schleimer, Mahmood K. Razavi, Alexander Gombert, Irwin M. Toonder, Mamdouh Afify, Mohammad E. Barbati, Ali Modabber, Suat Doganci, Houman Jalaie
Publikováno v: European Journal of Vascular and Endovascular Surgery. 62:276-283
Objective The impact of stent design on venous patency is not well studied. The purpose of this study was to investigate the effect of stent material burden on endothelial coverage of stented venous segments, which may contribute to vessel healing an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27ff2205a12349564fd7019f3122d05
https://doi.org/10.1016/j.ejvs.2021.04.001
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10
Apolipoprotein E4 Is Associated with Right Ventricular Dysfunction in Dilated Cardiomyopathy—An Animal and In-Human Comparative Study
Autor: Ioana Streata, David Schumacher, Nicole Schaaps, Rodica Diaconu, Teddy El-Khoury, Felix Vogt, Roberta Florescu, Sakine Simsekyilmaz, Ionut Donoiu, Mihai Ioana, Peter Boor, Elisa A. Liehn, Mamdouh Afify, Constantin Militaru, Anne Cornelissen
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 9688, p 9688 (2021)
International Journal of Molecular Sciences
International journal of molecular sciences 22(18), 9688 (2021). doi:10.3390/ijms22189688 special issue: "Special issue "Heart failure: from molecular basis to therapy 2.0" / special issue editors: Francesco Fedele, guest editor; Paul J. Mather, guest editor"
Volume 22
Issue 18
ApoE abnormality represents a well-known risk factor for cardiovascular diseases. Beyond its role in lipid metabolism, novel studies demonstrate a complex involvement of apoE in membrane homeostasis and signaling as well as in nuclear transcription.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de17983e26759768eabf2f9bd0a5239
https://www.mdpi.com/1422-0067/22/18/9688
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