Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mamatha Mahadevappa"'
Autor:
George Stephanopoulos, Ilias Alevizos, Janet A. Warrington, Daehee Hwang, Hiroe Ohyama, Jatin Misra, David T.W. Wong, Mamatha Mahadevappa, William A. Schmitt, Gregory Stephanopoulos, Randy Todd
Publikováno v:
Oral Oncology. 39:259-268
Genome-wide and high-throughput functional genomic tools offer the potential of identifying disease-associated genes and dissecting disease regulatory patterns. There is a need for a set of systematic bioinformatic tools that handles efficiently a la
Autor:
Rosalie Nolley, Zuxiong Chen, Janet A. Warrington, Zhenbin Fan, Thomas A. Stamey, Mamatha Mahadevappa, Zhaomei Zhang, Mitchell C. Caldwell, John E. McNEAL
Publikováno v:
Journal of Urology. 169:1316-1319
Recent studies have shown that hepsin, a serine protease, is over expressed in prostate cancers, implicating hepsin activity in tumor invasion. Using microarray technology we have previously identified 22 genes that were up-regulated in high grade pr
Publikováno v:
The Journal of Molecular Diagnostics. 5:9-14
Gene expression profiling using high density oligonucleotide arrays is a powerful method to generate an unbiased survey of a cell’s transcriptional landscape. Increasingly complex biological questions require that this approach be applicable to the
Autor:
Janet A. Warrington, Zhenbin Fan, Thomas A. Stamey, Rosalie Nolley, Mitchell C. Caldwell, Mamatha Mahadevappa, Zhaomei Zhang, Zuxiong Chen, John E. McNEAL
Publikováno v:
Journal of Urology. 166:2171-2177
Purpose: Because Gleason grade 4/5 cancer is the primary cause of failure to cure prostate cancer, we examined the molecular profiles of this high grade cancer in search of potentially new therapeutic interventions as well as better serum markers tha
Recombination of alleles conferring specific resistance to powdery mildew at the Mla locus in barley
Publikováno v:
Genome. 37:460-468
In barley (Hordeum vulgare L.), the Mla locus conditions reaction to the powdery mildew fungus Erysiphe graminis f.sp. hordei. Enrichment for genetic recombinants in the Mla region is possible by screening for recombination events between the flankin
Autor:
Mitchell C. Caldwell, Mamatha Mahadevappa, Thomas A. Stamey, Zhaomei Zhang, John E. McNEAL, Rosalie Nolley, Janet A. Warrington, Zhenbin Fan, Zuxiong Chen
Publikováno v:
The Journal of urology. 170(6 Pt 1)
We examined the variation in gene expression profiles of prostate cancer caused by zone specific genes.Ten normal central zone, 10 transition zone (benign prostatic hyperplasia) and 6 normal peripheral zone tissues from radical retropubic prostatecto
Autor:
Hiroe, Ohyama, Mamatha, Mahadevappa, Heikki, Luukkaa, Randy, Todd, Janet A, Warrington, David T W, Wong
Publikováno v:
Methods in enzymology. 356
Autor:
Daniel J. Black, Rachel M. Gonzalez-Hernandez, Mamatha Mahadevappa, Piri Welcsh, Elizabeth M. Swisher, Janet A. Warrington, Mary Claire King, Ming K. Lee
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 99(11)
Loss of function of BRCA1 caused by inherited mutation and tissue-specific somatic mutation leads to breast and ovarian cancer. Nearly all BRCA1 germ-line mutations involve truncation or loss of the C-terminal BRCT transcriptional activation domain,
Autor:
Richard E. Pratt, George Stephanopoulos, William P. Dillon, Edgar L. Milford, Gregory Stephanopoulos, Jatin Misra, Matthew P. Frosch, Kailin F. Lee, Takumi Yoshida, Kathryn E. Clark, Steven R. Gullans, Robert L. Hong, Marcy E. MacDonald, George L. Mutter, Mamatha Mahadevappa, Fernando Dangond, Janet A. Warrington, Christopher P. Crum, Roderick V. Jensen, Li Li Hsiao, Peter M. Haverty, Raphael Bueno, Zhiping Weng
Publikováno v:
Physiological genomics. 7(2)
This study creates a compendium of gene expression in normal human tissues suitable as a reference for defining basic organ systems biology. Using oligonucleotide microarrays, we analyze 59 samples representing 19 distinct tissue types. Of ∼7,000 g