Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Malwina Strenkowska"'
Autor:
Olga Perzanowska, Maciej Majewski, Malwina Strenkowska, Paulina Głowala, Mariusz Czarnocki-Cieciura, Maciej Mazur, Joanna Kowalska, Jacek Jemielity
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Gold nanoparticles (AuNPs) decorated with biologically relevant molecules have variety of applications in optical sensing of bioanalytes. Coating AuNPs with small nucleotides produces particles with high stability in water, but functionality
Externí odkaz:
https://doaj.org/article/286d0e6347724af1a495387a20c2c837
Autor:
Maciej Majewski, Joanna Kowalska, Paulina Głowala, Olga Perzanowska, Malwina Strenkowska, Maciej Mazur, Mariusz Czarnocki-Cieciura, Jacek Jemielity
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Gold nanoparticles (AuNPs) decorated with biologically relevant molecules have variety of applications in optical sensing of bioanalytes. Coating AuNPs with small nucleotides produces particles with high stability in water, but functionality-compatib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e50daa218f082b281cf9578ca1043f9
https://doi.org/10.1038/s41598-021-94983-y
https://doi.org/10.1038/s41598-021-94983-y
Autor:
Edward Darzynkiewicz, Corina Nicola, Malwina Strenkowska, Elzbieta Bojarska, Zbigniew M. Darzynkiewicz, Maciej Lukaszewicz, Maciej Maciejczyk, Andreas Kuhn, Anna Wypijewska del Nogal, Jacek Jemielity, Joanna Zuberek, Joanna Kowalska, Ugur Sahin, Marcin Ziemniak, Robert E. Rhoads, Janina Buck
Publikováno v:
Nucleic Acids Research
Modified mRNA cap analogs aid in the study of mRNA-related processes and may enable creation of novel therapeutic interventions. We report the synthesis and properties of 11 dinucleotide cap analogs bearing a single boranophosphate modification at ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7915ad1a90826b04cbbdc16c6a6a2e68
http://europepmc.org/articles/PMC4176373
http://europepmc.org/articles/PMC4176373
Publikováno v:
Future Medicinal Chemistry. 5:1141-1172
Cap analogs are chemically modified derivatives of the unique cap structure present at the 5´ end of all eukaryotic mRNAs and several non-coding RNAs. Until recently, cap analogs have served primarily as tools in the study of RNA metabolism. Continu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3450d7efa03784f255e4dd0ce3c87389
https://doi.org/10.4155/fmc.13.96
https://doi.org/10.4155/fmc.13.96
Publikováno v:
Collection Symposium Series.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f6561fef21c170a14abc6a80253c231
https://doi.org/10.1135/css201414287
https://doi.org/10.1135/css201414287
Autor:
Maciej Majewski, Joanna Kowalska, Joanna Zuberek, Renata Grzela, Malwina Strenkowska, Katarzyna Wnek, Maciej Lukaszewicz, Edward Darzynkiewicz, Andreas Kuhn, Jacek Jemielity, Ugur Sahin
Publikováno v:
Nucleic Acids Research
Along with a growing interest in mRNA-based gene therapies, efforts are increasingly focused on reaching the full translational potential of mRNA, as a major obstacle for in vivo applications is sufficient expression of exogenously delivered mRNA. On
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0311bce489f68ef315a4b5e1bc8e7f7
https://doi.org/10.1093/nar/gkw896
https://doi.org/10.1093/nar/gkw896
Publikováno v:
Organic letters. 14(18)
We describe a general method for the elongation of nucleoside oligophosphate chains by means of cyanoethyl (CE) phosphorimidazolides. Though the method requires a phosphorylation and subsequent deprotection reaction, both steps could be achieved in o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b0f8eb85d7adc5694ae65649f06ea7
https://pubmed.ncbi.nlm.nih.gov/22966945
https://pubmed.ncbi.nlm.nih.gov/22966945
Autor:
Joanna Zuberek, Maciej Lukaszewicz, Marcin Ziemniak, Jacek Jemielity, Joanna Kowalska, Edward Darzynkiewicz, Malwina Strenkowska
Publikováno v:
Collection Symposium Series.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1f2e728d268ba0ed03b239adcb2161a
https://doi.org/10.1135/css200810487
https://doi.org/10.1135/css200810487
Autor:
Malwina Strenkowska, Jacek Jemielity, Maciej Lukaszewicz, Joanna Kowalska, Marcin Ziemniak, Joanna Zuberek, Edward Darzynkiewicz
Publikováno v:
Nucleic Acids Symposium Series. 52:291-292
Two diastereomers of 7-methylguanosine 5'-O-(1-thiotriphosphate) have been synthesized and resolved by RP HPLC. Preliminary studies revealed that these new analogs of mRNA cap are characterized by high affinity for eIF4E, resistance towards DcpS pyro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63732857b56b4729a6c19b575c29c74f
https://doi.org/10.1093/nass/nrn147
https://doi.org/10.1093/nass/nrn147
Autor:
Wei Su, Joanna Kowalska, Jacek Jemielity, Robert E. Rhoads, Joanna Zuberek, Maciej Lukaszewicz, Malwina Strenkowska, Edward Darzynkiewicz
Publikováno v:
New Journal of Chemistry. 34:993
We describe the chemical synthesis and preliminary biophysical and biochemical characterization of a series of mRNA 5' end (cap) analogs designed as reagents for obtaining mRNA molecules with augmented translation efficiency and stability in vivo and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1309cfb1e5233d6295911d9c5fd86e05
https://doi.org/10.1039/b9nj00644c
https://doi.org/10.1039/b9nj00644c