Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Malvin Vien"'
Autor:
Lilia Leisle, Yanyan Xu, Eva Fortea, Sangyun Lee, Jason D Galpin, Malvin Vien, Christopher A Ahern, Alessio Accardi, Simon Bernèche
Publikováno v:
eLife, Vol 9 (2020)
The CLC family comprises H+-coupled exchangers and Cl- channels, and mutations causing their dysfunction lead to genetic disorders. The CLC exchangers, unlike canonical 'ping-pong' antiporters, simultaneously bind and translocate substrates through p
Externí odkaz:
https://doaj.org/article/c9ee0e91e4b94b3f972f512b0980c861
Autor:
Simon Bernèche, Eva Fortea, Sangyun Lee, Alessio Accardi, Jason D. Galpin, Malvin Vien, Lilia Leisle, Christopher A. Ahern, Yanyan Xu
Publikováno v:
eLife, Vol 9 (2020)
eLife 9, e51224 (2020). doi:10.7554/eLife.51224
eLife 9, e51224 (2020). doi:10.7554/eLife.51224
The CLC family comprises H; +; -coupled exchangers and Cl; -; channels, and mutations causing their dysfunction lead to genetic disorders. The CLC exchangers, unlike canonical 'ping-pong' antiporters, simultaneously bind and translocate substrates th
Publikováno v:
The Journal of General Physiology
A conserved glutamic acid residue is thought to occupy three different conformations in the transport pathway of CLC H+/Cl− exchangers. Vien et al. provide functional evidence that the most central of these three positions is adopted by CLC-ec1 dur
Autor:
Christopher A. Ahern, Jason D. Galpin, Simon Bernèche, Malvin Vien, Lilia Leisle, Eva Fortea, Alessio Accardi, Yanyan Xu
The CLC family of anion transporting proteins is comprised of secondary active H+-coupled exchangers and of Cl− channels. Both functional subtypes play key roles in human physiology, and mutations causing their dysfunction lead to numerous genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed1c5776a632537fdf9c4ab389860be
https://doi.org/10.1101/753954
https://doi.org/10.1101/753954
Publikováno v:
Biophysical Journal. 112:336a