Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Malti Kshirsagar"'
Autor:
Robert A. Soslow, Marisa R. Nucci, Andrew E. Horvai, Joseph T. Rabban, Andres A. Roma, Charles Zaloudek, Russell Vang, Jesse K. McKenney, Vinita Parkash, Charles M. Quick, Ankur R. Sangoi, Jacqueline Haas, Teri A. Longacre, Lora Hedrick Ellenson, Malti Kshirsagar, Anna Yemelyanova, Kay J. Park, W Glenn McCluggage, Ann K. Folkins, Andrew H. Beck, Joanne L. Rutgers, Krisztina Z. Hanley, Oluwole Fadare, Karuna Garg, Esther Oliva, Mamatha Chivukula
Publikováno v:
International Journal of Gynecological Pathology. 36:386-392
Distinguishing hyalinized stroma from osteoid production by a heterologous osteosarcomatous component can be challenging in gynecologic tract carcinosarcomas. As heterologous components in a carcinosarcoma may have prognostic and therapeutic implicat
Publikováno v:
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 36(2)
The novel marker special AT-rich sequence binding protein (SATB2) is highly sensitive for mesenchymal tumors with osteoblastic differentiation. However, SATB2 expression in gynecologic tract carcinosarcoma has not been previously explored. Given the
Publikováno v:
Journal of Oncology
Journal of Oncology, Vol 2012 (2012)
Journal of Oncology, Vol 2012 (2012)
DNA damage commonly occurs in cancer cells as a result of endogenous and tumor microenvironmental stress. In this study, we applied immunohistochemistry to study the expression of phosphorylated Chk2 (pChk2), a surrogate marker of the DNA damage resp
Autor:
Anna Yemelyanova, Malti Kshirsagar, Russell Vang, Robert J. Kurman, Dan Lu, Morgan A. Marks, Ie Ming Shih
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 24(9)
Immunohistochemical staining for p53 is used as a surrogate for mutational analysis in the diagnostic workup of carcinomas of multiple sites including ovarian cancers. Strong and diffuse immunoexpression of p53 is generally interpreted as likely indi
Autor:
Roland P.S. Kwok, Lili Zhao, J. Rebecca Liu, Lijun Tan, Abhishek Shukla, Malti Kshirsagar, Anthony W. Opipari
Publikováno v:
Cancer. 117(4)
BACKGROUND: Chemoresistance is the major factor limiting long-term treatment success in patients with epithelial ovarian cancers. Most cytotoxic drugs kill cells through apoptosis; therefore, defective execution of apoptotic pathways results in a dru
Autor:
Alexis Norris-Kirby, Kathleen M. Murphy, Malti Kshirsagar, Brigitte M. Ronnett, Jill M. Hagenkord
Publikováno v:
The Journal of molecular diagnostics : JMD. 12(4)
The vast majority of trisomies in spontaneous abortions (SAB) are single and of maternal origin, most frequently due to meiosis I errors. Triple trisomies are exceedingly rare (approximately 0.05% of spontaneous abortions), most often of maternal ori
Autor:
J. Rebecca Liu, Sayeema Daudi, Lijun Tan, Malti Kshirsagar, Jennifer M. Rhode, Heather Wahl, Kent A. Griffith
Publikováno v:
Gynecologic oncology. 116(1)
The differential metabolic phenotype observed between malignant and non-transformed cells may constitute a biochemical basis for therapeutic intervention. Increased glucose uptake is one of the major metabolic changes found in malignant tumors, a pro
Autor:
Lora Hedrick Ellenson, Kerby Shedden, Hidetaka Katabuchi, Samir M. Hanash, Kathleen R. Cho, Malti Kshirsagar, Hongfeng Yu, Rong Wu, Eric R. Fearon, David E. Misek, Donald R. Schwartz
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(6)
Purpose: Ovarian and uterine carcinomas manifest several differentiation patterns resembling those seen in nonneoplastic epithelia of the gynecologic tract. Specific oncogene and tumor suppressor gene defects have been associated with particular diff
Autor:
J. Rebecca Liu, Paul Loar, Malti Kshirsagar, Kent A. Griffith, Heather Wahl, Gabrielle Gossner
Publikováno v:
American Journal of Obstetrics and Gynecology. 202:371.e1-371.e8
Objective Up-regulation of glycolysis has been demonstrated in multiple tumor types and is believed to originate as an adaptive response to the selective pressure of the tumor microenvironment. We hypothesized that ovarian cancer cells are dependent