Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Maltez-Thomas A"'
Autor:
Richard C Lauer, Marc Barry, Tracey L Smith, Andrew Maltez Thomas, Jin Wu, Ruofei Du, Ji-Hyun Lee, Arpit Rao, Andrey S Dobroff, Marco A Arap, Diana N Nunes, Israel T Silva, Emmanuel Dias-Neto, Isan Chen, Dennis J McCance, Webster K Cavenee, Renata Pasqualini, Wadih Arap
Publikováno v:
eLife, Vol 12 (2023)
Background: We have previously shown that the long non-coding (lnc)RNA prostate cancer associated 3 (PCA3; formerly prostate cancer antigen 3) functions as a trans-dominant negative oncogene by targeting the previously unrecognized prostate cancer su
Externí odkaz:
https://doaj.org/article/54de7b4374ee4770b8c53468739cf642
Autor:
Niccolò Rossi, Karla A. Lee, Maria V. Bermudez, Alessia Visconti, Andrew Maltez Thomas, Laura A. Bolte, Johannes R. Björk, Laura Kist de Ruijter, Julia Newton-Bishop, Mark Harland, Heather M. Shaw, Mark Harries, Joseph Sacco, Ruth Board, Paul Lorigan, Elisabeth G.E. de Vries, Nicola Segata, Leonie Taams, Sophie Papa, Tim D. Spector, Paul Nathan, Rinse K. Weersma, Geke A.P. Hospers, Rudolf S.N. Fehrmann, Veronique Bataille, Mario Falchi
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104235- (2022)
Summary: Background: Inflammation can modulate tumour growth and progression, and influence clinical response to treatment. We investigated the potential of circulating inflammatory proteins for response stratification of immune checkpoint inhibitor
Externí odkaz:
https://doaj.org/article/2653e1f206bf4483825a0683e7b29ab7
Autor:
Francesco Asnicar, Andrew Maltez Thomas, Francesco Beghini, Claudia Mengoni, Serena Manara, Paolo Manghi, Qiyun Zhu, Mattia Bolzan, Fabio Cumbo, Uyen May, Jon G. Sanders, Moreno Zolfo, Evguenia Kopylova, Edoardo Pasolli, Rob Knight, Siavash Mirarab, Curtis Huttenhower, Nicola Segata
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The increasing amount of sequenced microbial genomes and metagenomes requires platforms for efficient integrated analysis. Here, Asnicar et al. present PhyloPhlAn 3.0, a pipeline allowing large-scale microbial genome characterization and phylogenetic
Externí odkaz:
https://doaj.org/article/e2c31a8ecbcb48b48383a2c552e60cf7
Autor:
Hang Phuong Pham, Douglas G McNeel, Laurence Zitvogel, Corentin Richard, Antoine Toubert, Guido Kroemer, Stéphane Culine, Karim Fizazi, Bertrand Routy, Lisa Derosa, Francesco Asnicar, Nicola Segata, Gladys Ferrere, Florent Ginhoux, Anne-Gaelle Goubet, Safae Terrisse, Kousuke Ueda, Andrew Maltez Thomas, Valentin Quiniou, Cassandra Thelemaque, Garett Dunsmore, Emmanuel Clave, Melissa Gamat-Huber, Satoru Yonekura, Conrad Rauber, Jean-Eudes Fahrner, Eugenie Pizzato, Pierre Ly, Marine Fidelle, Marine Mazzenga, Carolina Alves Costa Silva, Federica Armanini, Federica Pinto, Romain Daillère, Pierre Blanchard, Paule Opolon, Aymeric Silvin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background Prostate cancer (PC) responds to androgen deprivation therapy (ADT) usually in a transient fashion, progressing from hormone-sensitive PC (HSPC) to castration-resistant PC (CRPC). We investigated a mouse model of PC as well as specimens fr
Externí odkaz:
https://doaj.org/article/69ed34e3f16741d492e7a56953966a54
Autor:
Andrew Maltez Thomas, Nicola Segata
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-4 (2019)
Abstract Metagenomics allows exploration of aspects of a microbial community that were inaccessible by cultivation-based approaches targeting single microbes. Many new microbial taxa and genes have been discovered using metagenomics, but different ki
Externí odkaz:
https://doaj.org/article/df5a6d923eac4594a397959e495ac169
Autor:
Francesco Beghini, Lauren J McIver, Aitor Blanco-Míguez, Leonard Dubois, Francesco Asnicar, Sagun Maharjan, Ana Mailyan, Paolo Manghi, Matthias Scholz, Andrew Maltez Thomas, Mireia Valles-Colomer, George Weingart, Yancong Zhang, Moreno Zolfo, Curtis Huttenhower, Eric A Franzosa, Nicola Segata
Publikováno v:
eLife, Vol 10 (2021)
Culture-independent analyses of microbial communities have progressed dramatically in the last decade, particularly due to advances in methods for biological profiling via shotgun metagenomics. Opportunities for improvement continue to accelerate, wi
Externí odkaz:
https://doaj.org/article/e8af9fc8940a47069c3d3a8c162e1a4d
Autor:
Sonia Tarallo, Giulio Ferrero, Gaetano Gallo, Antonio Francavilla, Giuseppe Clerico, Alberto Realis Luc, Paolo Manghi, Andrew Maltez Thomas, Paolo Vineis, Nicola Segata, Barbara Pardini, Alessio Naccarati, Francesca Cordero
Publikováno v:
mSystems, Vol 5, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/a926247c049140b2bfe1166ee9176060
Autor:
Érica Barbosa Felestrino, Angélica Bianchini Sanchez, Washington Luiz Caneschi, Camila Gracyelle de Carvalho Lemes, Renata de Almeida Barbosa Assis, Isabella Ferreira Cordeiro, Natasha Peixoto Fonseca, Morghana Marina Villa, Izadora Tabuso Vieira, Luciana Hiromi Yoshino Kamino, Flávio Fonseca do Carmo, Aline Maria da Silva, Andrew Maltez Thomas, José Salvatore Leister Patané, Fernanda Carla Ferreira, Leandro Grassi de Freitas, Alessandro de Mello Varani, Jesus Aparecido Ferro, Robson Soares Silva, Nalvo Franco Almeida, Camila Carrião Machado Garcia, João Carlos Setubal, Leandro Marcio Moreira
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241546 (2020)
Here we present and analyze the complete genome of Alcaligenes faecalis strain Mc250 (Mc250), a bacterium isolated from the roots of Mimosa calodendron, an endemic plant growing in ferruginous rupestrian grasslands in Minas Gerais State, Brazil. The
Externí odkaz:
https://doaj.org/article/cc8c5c9af2134cf28f66bc081bf42b58
Autor:
Sonia Tarallo, Giulio Ferrero, Gaetano Gallo, Antonio Francavilla, Giuseppe Clerico, Alberto Realis Luc, Paolo Manghi, Andrew Maltez Thomas, Paolo Vineis, Nicola Segata, Barbara Pardini, Alessio Naccarati, Francesca Cordero
Publikováno v:
mSystems, Vol 4, Iss 5 (2019)
ABSTRACT Dysbiotic configurations of the human gut microbiota have been linked to colorectal cancer (CRC). Human small noncoding RNAs are also implicated in CRC, and recent findings suggest that their release in the gut lumen contributes to shape the
Externí odkaz:
https://doaj.org/article/f37f508f65fc4e14be8522387a8395b4
Autor:
José Luís Fachi, Jaqueline de Souza Felipe, Laís Passariello Pral, Bruna Karadi da Silva, Renan Oliveira Corrêa, Mirella Cristiny Pereira de Andrade, Denise Morais da Fonseca, Paulo José Basso, Niels Olsen Saraiva Câmara, Éricka Lorenna de Sales e Souza, Flaviano dos Santos Martins, Suzana Eiko Sato Guima, Andrew Maltez Thomas, João Carlos Setubal, Yuli Thamires Magalhães, Fábio Luis Forti, Thamiris Candreva, Hosana Gomes Rodrigues, Marcelo Bispo de Jesus, Sílvio Roberto Consonni, Alessandro dos Santos Farias, Patrick Varga-Weisz, Marco Aurélio Ramirez Vinolo
Publikováno v:
Cell Reports, Vol 27, Iss 3, Pp 750-761.e7 (2019)
Summary: Antibiotic-induced dysbiosis is a key factor predisposing intestinal infection by Clostridium difficile. Here, we show that interventions that restore butyrate intestinal levels mitigate clinical and pathological features of C. difficile-ind
Externí odkaz:
https://doaj.org/article/9c4fc043dfbe4f37bba8f567ccb37dd6