Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Malte P Suppli"'
Autor:
Magnus F G Grøndahl, Jonatan I Bagger, Malte P Suppli, Gerrit Van Hall, Nicolai J W Albrechtsen, Jens J Holst, Tina Vilsbøll, Mikkel B Christensen, Asger B Lund, Filip K Knop
Publikováno v:
Endocrine Connections, Vol 13, Iss 3, Pp 1-7 (2024)
Objective: In obesity and type 2 diabetes, hyperglucagonaemia may be caused by elevated levels of glucagonotropic amino acids due to hepatic glucagon resistance at the level of amino acid turnover. Here, we investigated the effect of exogenous glucag
Externí odkaz:
https://doaj.org/article/00f941a57208446d86eaddb4eb0f81a0
Autor:
Iben Rix, Marie L Johansen, Asger Lund, Malte P Suppli, Elizaveta Chabanova, Gerrit van Hall, Jens J Holst, Nicolai J Wewer Albrechtsen, Caroline Kistorp, Filip K Knop
Publikováno v:
Endocrine Connections, Vol 13, Iss 1, Pp 1-11 (2023)
Aims: Hyperglucagonaemia contributes to the pathophysiology in type 2 diabetes (T2D), but the mechanisms behind the inappropriate glucagon secretion are not fully understood. Glucagon and amino acids are regulated in a feedback loop referred to as th
Externí odkaz:
https://doaj.org/article/6f1c147d2ee0469ab8bf0a86ef0c342e
Autor:
Henrik H. Hansen, Helene M. Ægidius, Denise Oró, Simon S. Evers, Sara Heebøll, Peter Lykke Eriksen, Karen Louise Thomsen, Anja Bengtsson, Sanne S. Veidal, Michel Feigh, Malte P. Suppli, Filip K. Knop, Henning Grønbæk, Diego Miranda, James L. Trevaskis, Niels Vrang, Jacob Jelsing, Kristoffer T. G. Rigbolt
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Animal models of non-alcoholic steatohepatitis (NASH) are important tools in preclinical research and drug discovery. Gubra-Amylin NASH (GAN) diet-induced obese (DIO) mice represent a model of fibrosing NASH. The present study dir
Externí odkaz:
https://doaj.org/article/738511df0fdc4d36be87fd7875e0fda9
Autor:
Monika Lewinska, PhD, Alvaro Santos-Laso, PhD, Enara Arretxe, PhD, Cristina Alonso, PhD, Ekaterina Zhuravleva, PhD, Raul Jimenez-Agüero, MD, PhD, Emma Eizaguirre, MD, PhD, María Jesús Pareja, MD, PhD, Manuel Romero-Gómez, MD, PhD, Marco Arrese Jimenez, MD, PhD, Malte P. Suppli, MD, PhD, Filip K. Knop, MD, PhD, Stine Karlsen Oversoe, MD, PhD, Gerda Elisabeth Villadsen, MD, PhD, Thomas Decaens, MD, PhD, Flair Jose Carrilho, MD, PhD, Claudia PMS de Oliveira, MD, PhD, Bruno Sangro, MD, PhD, Rocio I.R. Macias, MD, PhD, Jesus M. Banales, PhD, Jesper B. Andersen, PhD
Publikováno v:
EBioMedicine, Vol 73, Iss , Pp 103661- (2021)
Background: Non-alcoholic fatty liver disease (NAFLD) is affecting more people globally. Indeed, NAFLD is a spectrum of metabolic dysfunctions that can progress to hepatocellular carcinoma (NAFLD-HCC). This development can occur in a non-cirrhotic li
Externí odkaz:
https://doaj.org/article/a98663c5714b4b39a2da1a493b1539b3
Autor:
Malte Palm Suppli, Jonatan Ising Bagger, Benjamin Lelouvier, Amandine Broha, Mia Demant, Merete Juhl Kønig, Charlotte Strandberg, Asger Lund, Tina Vilsbøll, Filip Krag Knop
Publikováno v:
JHEP Reports, Vol 3, Iss 4, Pp 100299- (2021)
Background & Aims: Dysbiosis of the gut microbiota in response to an energy-rich Western diet and the potential leak of bacteria and/or bacterial products from the intestine to the liver is perceived as a potential risk factor for the development of
Externí odkaz:
https://doaj.org/article/a0196d97fb6e4e1b998666e0f93559f2
Autor:
Amalie R. Lanng, Ulrik Becker, Jens J. Holst, Tina Vilsbøll, Joachim Knop, Sigrid Bergmann, Jonatan I. Bagger, Lærke S. Gasbjerg, Lise Gether, Niels B. Dalsgaard, Magnus F. Grøndahl, Signe Foghsgaard, Matthew P. Gillum, Mia Demant, Malte P. Suppli, Nicolai J. Wewer Albrechtsen, Merete J Kønig, Charlotte Strandberg, Henning Grønbæk, Martin L. Thomasen, Filip K. Knop
Publikováno v:
Demant, M, Suppli, M P, Foghsgaard, S, Gether, L, Grøndahl, M F G, Dalsgaard, N B, Bergmann, S S, Lanng, A R, Gasbjerg, L S, Thomasen, M, Bagger, J I, Strandberg, C, Kønig, M J, Grønbæk, H, Becker, U, Wewer Albrechtsen, N J, Holst, J J, Knop, J, Gillum, M P, Vilsbøll, T & Knop, F K 2021, ' Metabolic effects of 1-week binge drinking and fast food intake during Roskilde Festival in young healthy male adults ', European Journal of Endocrinology, vol. 185, no. 1, pp. 23-32 . https://doi.org/10.1530/EJE-21-0122
Demant, M, Suppli, M P, Foghsgaard, S, Gether, L, Grøndahl, M F G, Dalsgaard, N B, Bergmann, S S, Lanng, A R, Gasbjerg, L S, Thomasen, M, Bagger, J I, Strandberg, C, Kønig, M J, Grønbæk, H, Becker, U, Holst, J J, Knop, J, Gillum, M P, Vilsbøll, T & Knop, F K 2021, ' Metabolic effects of 1-week binge drinking and fast food intake during Roskilde Festival in young healthy male adults ', European Journal of Endocrinology, vol. 185, no. 1, pp. 23-32 . https://doi.org/10.1530/EJE-21-0122
Demant, M, Suppli, M P, Foghsgaard, S, Gether, L, Grøndahl, M F G, Dalsgaard, N B, Bergmann, S S, Lanng, A R, Gasbjerg, L S, Thomasen, M, Bagger, J I, Strandberg, C, Kønig, M J, Grønbæk, H, Becker, U, Holst, J J, Knop, J, Gillum, M P, Vilsbøll, T & Knop, F K 2021, ' Metabolic effects of 1-week binge drinking and fast food intake during Roskilde Festival in young healthy male adults ', European Journal of Endocrinology, vol. 185, no. 1, pp. 23-32 . https://doi.org/10.1530/EJE-21-0122
Aims/hypothesis Metabolic effects of intermittent unhealthy lifestyle in young adults are poorly studied. We investigated the gluco-metabolic and hepatic effects of participation in Roskilde Festival (1 week of binge drinking and junk food consumptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6360ee13ff03cdf01cb4fca67796d4
https://doi.org/10.1530/eje-21-0122
https://doi.org/10.1530/eje-21-0122
Autor:
Tina Vilsbøll, Malte P. Suppli, Charlotte Strandberg, Jill Levin Langhoff, Nicolai J. Wewer Albrechtsen, Gerrit van Hall, Filip K. Knop, Asger Lund, Jens J. Holst, Mia Demant, Merete J Kønig, Jonatan I. Bagger, Kristoffer T.G. Rigbolt
Publikováno v:
Diabetes. 69:1090-1099
Glucagon secretion is regulated by circulating glucose, but it has turned out that amino acids also play an important role and that hepatic amino acid metabolism and glucagon are linked in a mutual feedback cycle, the liver–α-cell axis. On the bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8a92a552db05d9def69ee16d00a7bb
https://doi.org/10.2337/db19-0715
https://doi.org/10.2337/db19-0715
Autor:
Michael M. Richter, Katrine D. Galsgaard, Emilie Elmelund, Filip K. Knop, Malte P. Suppli, Jens J. Holst, Marie Winther-Sørensen, Sasha A.S. Kjeldsen, Nicolai J. Wewer Albrechtsen
Publikováno v:
Diabetes. 71(9)
Glucagon and insulin are the main regulators of blood glucose. While the actions of insulin are extensively mapped, less is known about glucagon. Besides glucagon’s role in glucose homeostasis, there are additional links between the pancreatic α-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f983f0f7dda76cfb37f994eebd41b4f
https://pubmed.ncbi.nlm.nih.gov/35657688
https://pubmed.ncbi.nlm.nih.gov/35657688
Autor:
Jonatan I. Bagger, Tina Vilsbøll, Filip K. Knop, Benjamin Lelouvier, Malte P. Suppli, Charlotte Strandberg, Amandine Broha, Mia Demant, Merete J Kønig, Asger Lund
Publikováno v:
JHEP Reports, Vol 3, Iss 4, Pp 100299-(2021)
JHEP Reports
Suppli, M P, Bagger, J I, Lelouvier, B, Broha, A, Demant, M, Kønig, M J, Strandberg, C, Lund, A, Vilsbøll, T & Knop, F K 2021, ' Hepatic microbiome in healthy lean and obese humans ', JHEP Reports, vol. 3, no. 4, 100299 . https://doi.org/10.1016/j.jhepr.2021.100299
JHEP Reports
Suppli, M P, Bagger, J I, Lelouvier, B, Broha, A, Demant, M, Kønig, M J, Strandberg, C, Lund, A, Vilsbøll, T & Knop, F K 2021, ' Hepatic microbiome in healthy lean and obese humans ', JHEP Reports, vol. 3, no. 4, 100299 . https://doi.org/10.1016/j.jhepr.2021.100299
Background & Aims Dysbiosis of the gut microbiota in response to an energy-rich Western diet and the potential leak of bacteria and/or bacterial products from the intestine to the liver is perceived as a potential risk factor for the development of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23eee827bacdf1b0e217e24af3bd81a5
http://www.sciencedirect.com/science/article/pii/S2589555921000756
http://www.sciencedirect.com/science/article/pii/S2589555921000756
Autor:
Malte P. Suppli, Peter Lykke Eriksen, Kristoffer T. G. Rigbolt, Sanne Skovgård Veidal, Hendrik Vilstrup, Karen Louise Thomsen, Fillip Krag Knop, Michael Sørensen, Sara Heebøll
Publikováno v:
Eriksen, P L, Vilstrup, H, Rigbolt, K, Suppli, M P, Sørensen, M, Heebøll, S, Veidal, S S, Knop, F K & Thomsen, K L 2019, ' Non-alcoholic fatty liver disease alters expression of genes governing hepatic nitrogen conversion ', Liver International, vol. 39, no. 11, pp. 2094-2101 . https://doi.org/10.1111/liv.14205
Background & Aims: We recently showed that the functional capacity for ureagenesis is deficient in non-alcoholic fatty liver disease (NAFLD) patients. The aim of this study was to assess expression of urea cycle-related genes to elucidate a possible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b6eda02378f2bd02db4dc62ba621a0
https://doi.org/10.1111/liv.14205
https://doi.org/10.1111/liv.14205