The Effect of Obstructive Sleep Apnea and Continuous Positive Airway Pressure Therapy on Skeletal Muscle Lipid Content in Obese and Nonobese Men

Autor: Ulrich Koehler, Olaf Hildebrandt, Malte Keller, Nico Laur, Alexander Koenig, Hans-Peter Deigner, Wulf Hildebrandt, Peter H. Kann, Raphael Boneberg, Lena Hannemann, Andreas H. Mahnken, Johannes T. Heverhagen, Hans Schwarzbach, Ralf Kinscherf

Publikováno v: Journal of the Endocrine Society
Koenig, Alexander M; Koehler, Ulrich; Hildebrandt, Olaf; Schwarzbach, Hans; Hannemann, Lena; Boneberg, Raphael; Heverhagen, Johannes; Mahnken, Andreas H; Keller, Malte; Kann, Peter H; Deigner, Hans-Peter; Laur, Nico; Kinscherf, Ralf; Hildebrandt, Wulf (2021). The Effect of Obstructive Sleep Apnea and Continuous Positive Airway Pressure Therapy on Skeletal Muscle Lipid Content in Obese and Nonobese Men. Journal of the Endocrine Society, 5(8), bvab082. Oxford University Press 10.1210/jendso/bvab082

Obstructive sleep apnea (OSA), independently of obesity (OBS), predisposes to insulin resistance (IR) for largely unknown reasons. Because OSA-related intermittent hypoxia triggers lipolysis, overnight increases in circulating free fatty acids (FFAs)

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