Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Malte Kühnemund"'
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Akademický článek
Targeted DNA sequencing and in situ mutation analysis using mobile phone microscopy
Autor: Malte Kühnemund, Qingshan Wei, Evangelia Darai, Yingjie Wang, Iván Hernández-Neuta, Zhao Yang, Derek Tseng, Annika Ahlford, Lucy Mathot, Tobias Sjöblom, Aydogan Ozcan, Mats Nilsson
Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
On-site diagnostics technologies allow for rapid, cost-effective diagnosis with a particular importance for remote communities. Here the authors demonstrate the use of mobile phone based microscopy for targeted DNA sequencing andin situpoint mutation
Externí odkaz: https://doaj.org/article/747627d1b30b4d9285a595720e9b3738
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2
A community-based transcriptomics classification and nomenclature of neocortical cell types
Autor: Rafael Yuste, Michael Hawrylycz, Nadia Aalling, Argel Aguilar-Valles, Detlev Arendt, Ruben Armañanzas, Giorgio A. Ascoli, Concha Bielza, Vahid Bokharaie, Tobias Borgtoft Bergmann, Irina Bystron, Marco Capogna, YoonJeung Chang, Ann Clemens, Christiaan P. J. de Kock, Javier DeFelipe, Sandra Esmeralda Dos Santos, Keagan Dunville, Dirk Feldmeyer, Richárd Fiáth, Gordon James Fishell, Angelica Foggetti, Xuefan Gao, Parviz Ghaderi, Natalia A. Goriounova, Onur Güntürkün, Kenta Hagihara, Vanessa Jane Hall, Moritz Helmstaedter, Suzana Herculano-Houzel, Markus M. Hilscher, Hajime Hirase, Jens Hjerling-Leffler, Rebecca Hodge, Josh Huang, Rafiq Huda, Konstantin Khodosevich, Ole Kiehn, Henner Koch, Eric S. Kuebler, Malte Kühnemund, Pedro Larrañaga, Boudewijn Lelieveldt, Emma Louise Louth, Jan H. Lui, Huibert D. Mansvelder, Oscar Marin, Julio Martinez-Trujillo, Homeira Moradi Chameh, Alok Nath Mohapatra, Hermany Munguba, Maiken Nedergaard, Pavel Němec, Netanel Ofer, Ulrich Gottfried Pfisterer, Samuel Pontes, William Redmond, Jean Rossier, Joshua R. Sanes, Richard H. Scheuermann, Esther Serrano-Saiz, Jochen F. Staiger, Peter Somogyi, Gábor Tamás, Andreas Savas Tolias, Maria Antonietta Tosches, Miguel Turrero García, Christian Wozny, Thomas V. Wuttke, Yong Liu, Juan Yuan, Hongkui Zeng, Ed Lein
Publikováno v: Yuste, R, Hawrylycz, M, Aalling, N, Arendt, D, Armananzas, R, Ascoli, G, Bielza, C, Bokharaie, V, Bergmann, T, Bystron, I, Capogna, M, Chang, Y, Clemens, A, Kock, C D, DeFelipe, J, Santos, S D, Dunville, K, Feldmeyer, D, Fiath, R, Fishell, G, Foggetti, A, Gao, X, Ghaderi, P, Gunturkun, O, Hall, V J, Helmstaedter, M, Herculano-Houzel, S, Hilscher, M, Hirase, H, Hjerling-Leffler, J, Hodge, R, Huang, Z J, Huda, R, Juan, Y, Khodosevich, K, Kiehn, O, Koch, H, Kuebler, E, Kuhnemund, M, Larranaga, P, Lelieveldt, B, Louth, E L, Lui, J, Mansvelder, H, Marin, O, Martínez-Trujillo, J, Moradi, H, Goriounova, N, Mohapatra, A, Nedergaard, M, Němec, P, Ofer, N, Pfisterer, U, Pontes, S, Redmond, W, Rossier, J, Sanes, J, Scheuermann, R, Saiz, E S, Somogyi, P, Tamás, G, Tolias, A, Tosches, M, Garcia, M T, Aguilar-Valles, A, Munguba, H, Wozny, C, Wuttke, T, Yong, L, Zeng, H & Lein, E S 2020, ' A community-based transcriptomics classification and nomenclature of neocortical cell types ', Nature Neuroscience . https://doi.org/10.1038/s41593-020-0685-8
Digital.CSIC. Repositorio Institucional del CSIC
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Yuste, R, Hawrylycz, M, Aalling, N, Aguilar-Valles, A, Arendt, D, Arnedillo, R A, Ascoli, G A, Bielza, C, Bokharaie, V, Bergmann, T B, Bystron, I, Capogna, M, Chang, Y, Clemens, A, de Kock, C P J, DeFelipe, J, Dos Santos, S E, Dunville, K, Feldmeyer, D, Fiáth, R, Fishell, G J, Foggetti, A, Gao, X, Ghaderi, P, Goriounova, N A, Güntürkün, O, Hagihara, K, Hall, V J, Helmstaedter, M, Herculano, S, Hilscher, M M, Hirase, H, Hjerling-Leffler, J, Hodge, R, Huang, J, Huda, R, Khodosevich, K, Kiehn, O, Koch, H, Kuebler, E S, Kühnemund, M, Larrañaga, P, Lelieveldt, B, Louth, E L, Lui, J H, Mansvelder, H D, Marin, O, Martinez-Trujillo, J, Moradi Chameh, H, Nath, A, Nedergaard, M, Němec, P, Ofer, N, Pfisterer, U G, Pontes, S, Redmond, W, Rossier, J, Sanes, J R, Scheuermann, R, Serrano-Saiz, E, Steiger, J F, Somogyi, P, Tamás, G, Tolias, A S, Tosches, M A, García, M T, Vieira, H M, Wozny, C, Wuttke, T V, Yong, L, Yuan, J, Zeng, H & Lein, E 2020, ' A community-based transcriptomics classification and nomenclature of neocortical cell types ', Nature Neuroscience, vol. 23, no. 12, pp. 1456-1468 . https://doi.org/10.1038/s41593-020-0685-8
Nature Neuroscience, 23(12), 1456-1468. Nature Publishing Group
Nature Neuroscience
Nature Neuroscience, ISSN 1097-6256, 2020-03, Vol. 23
Yuste, R, Hawrylycz, M, Aalling, N, Aguilar-valles, A, Arendt, D, Arnedillo, R A, Ascoli, G A, Bielza, C, Bokharaie, V, Bergmann, T B, Bystron, I, Capogna, M, Chang, Y, Clemens, A, De Kock, C P J, Defelipe, J, Dos Santos, S E, Dunville, K, Feldmeyer, D, Fiáth, R, Fishell, G J, Foggetti, A, Gao, X, Ghaderi, P, Goriounova, N A, Güntürkün, O, Hagihara, K, Hall, V J, Helmstaedter, M, Herculano, S, Hilscher, M M, Hirase, H, Hjerling-leffler, J, Hodge, R, Huang, J, Huda, R, Khodosevich, K, Kiehn, O, Koch, H, Kuebler, E S, Kühnemund, M, Larrañaga, P, Lelieveldt, B, Louth, E L, Lui, J H, Mansvelder, H D, Marin, O, Martinez-trujillo, J, Moradi Chameh, H, Nath, A, Nedergaard, M, Němec, P, Ofer, N, Pfisterer, U G, Pontes, S, Redmond, W, Rossier, J, Sanes, J R, Scheuermann, R, Serrano-saiz, E, Steiger, J F, Somogyi, P, Tamás, G, Tolias, A S, Tosches, M A, García, M T, Vieira, H M, Wozny, C, Wuttke, T V, Yong, L, Yuan, J, Zeng, H & Lein, E 2020, ' A community-based transcriptomics classification and nomenclature of neocortical cell types ', Nature Neuroscience, vol. 23, pp. 1456-1468 . https://doi.org/10.1038/s41593-020-0685-8
Nat Neurosci
Nature neuroscience 23(12), 1456-1468 (2020). doi:10.1038/s41593-020-0685-8 special issue: "Focus on neuroscience methods"
Nature Neuroscience, 23(12), 1456-1468. NATURE RESEARCH
Physiology and Pharmacology Publications
Nature neuroscience, vol 23, iss 12
To understand the function of cortical circuits it is necessary to classify their underlying cellular diversity. Traditional attempts based on comparing anatomical or physiological features of neurons and glia, while productive, have not resulted in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99f5b48e1716cf233a9dc0f39816d98
https://www.pure.ed.ac.uk/ws/files/157037447/NN_2020acceptedClemens_1_.pdf
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Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer's Disease
Autor: Sriram Balusu, José Fernández Navarro, Ashley Lu, Takaomi C. Saido, Katleen Craessaerts, Carlo Sala Frigerio, An Snellinx, Nikky Corthout, Inge Huitinga, Iryna Voytyuk, Bart De Strooper, Benjamin Pavie, Wei Ting Chen, Evgenia Salta, Aleksandra Jurek, Renzo Mancuso, Leen Wolfs, Jana Lalakova, Mark Fiers, Xiaoyan Qian, Joakim Lundeberg, Malte Kühnemund, Sebastian Munck
Publikováno v: Cell
Cell, 182, 976-991. Elsevier B.V.
Although complex inflammatory-like alterations are observed around the amyloid plaques of Alzheimer's disease (AD), little is known about the molecular changes and cellular interactions that characterize this response. We investigate here, in an AD m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04cebc5904b5e6687f2d8f4b61aab97
https://lirias.kuleuven.be/handle/123456789/657727
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Detection of bacterial pathogens and drug resistance markers using Rolling circle amplification v1
Autor: Malte Kühnemund, Ivan Hernandez, Mohd Istiaq Sharif, Matteo Cornaglia, Martin A.M. Gijs, Mats Nilsson
Here is described the protocol used to detect bacteria and antibiotic resistance markers using padlock probes and Rolling circle amplification. This method allows for single-molecule/digital quantification in a semi-quantitative way.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c1e92aa9a8a87bf7fb1ad7af6fc2b9b
https://doi.org/10.17504/protocols.io.zp8f5rw
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Publisher Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types
Autor: Rafael Yuste, Michael Hawrylycz, Nadia Aalling, Argel Aguilar-Valles, Detlev Arendt, Ruben Armananzas Arnedillo, Giorgio A. Ascoli, Concha Bielza, Vahid Bokharaie, Tobias Borgtoft Bergmann, Irina Bystron, Marco Capogna, Yoonjeung Chang, Ann Clemens, Christiaan P. J. de Kock, Javier DeFelipe, Sandra Esmeralda Dos Santos, Keagan Dunville, Dirk Feldmeyer, Richárd Fiáth, Gordon James Fishell, Angelica Foggetti, Xuefan Gao, Parviz Ghaderi, Natalia A. Goriounova, Onur Güntürkün, Kenta Hagihara, Vanessa Jane Hall, Moritz Helmstaedter, Suzana Herculano, Markus M. Hilscher, Hajime Hirase, Jens Hjerling-Leffler, Rebecca Hodge, Josh Huang, Rafiq Huda, Konstantin Khodosevich, Ole Kiehn, Henner Koch, Eric S. Kuebler, Malte Kühnemund, Pedro Larrañaga, Boudewijn Lelieveldt, Emma Louise Louth, Jan H. Lui, Huibert D. Mansvelder, Oscar Marin, Julio Martinez-Trujillo, Homeira Moradi Chameh, Alok Nath, Maiken Nedergaard, Pavel Němec, Netanel Ofer, Ulrich Gottfried Pfisterer, Samuel Pontes, William Redmond, Jean Rossier, Joshua R. Sanes, Richard Scheuermann, Esther Serrano-Saiz, Jochen F. Steiger, Peter Somogyi, Gábor Tamás, Andreas Savas Tolias, Maria Antonietta Tosches, Miguel Turrero García, Hermany Munguba Vieira, Christian Wozny, Thomas V. Wuttke, Liu Yong, Juan Yuan, Hongkui Zeng, Ed Lein
Publikováno v: Yuste, R, Hawrylycz, M, Aalling, N, Aguilar-Valles, A, Arendt, D, Arnedillo, R A, Ascoli, G A, Bielza, C, Bokharaie, V, Bergmann, T B, Bystron, I, Capogna, M, Chang, Y, Clemens, A, de Kock, C P J, DeFelipe, J, Dos Santos, S E, Dunville, K, Feldmeyer, D, Fiáth, R, Fishell, G J, Foggetti, A, Gao, X, Ghaderi, P, Goriounova, N A, Güntürkün, O, Hagihara, K, Hall, V J, Helmstaedter, M, Herculano, S, Hilscher, M M, Hirase, H, Hjerling-Leffler, J, Hodge, R, Huang, J, Huda, R, Khodosevich, K, Kiehn, O, Koch, H, Kuebler, E S, Kühnemund, M, Larrañaga, P, Lelieveldt, B, Louth, E L, Lui, J H, Mansvelder, H D, Marin, O, Martinez-Trujillo, J, Moradi Chameh, H, Nath, A, Nedergaard, M, Němec, P, Ofer, N, Pfisterer, U G, Pontes, S, Redmond, W, Rossier, J, Sanes, J R, Scheuermann, R, Serrano-Saiz, E, Steiger, J F, Somogyi, P, Tamás, G, Tolias, A S, Tosches, M A, García, M T, Vieira, H M, Wozny, C, Wuttke, T V, Yong, L, Yuan, J, Zeng, H & Lein, E 2021, ' Publisher Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types ', Nature Neuroscience, vol. 24, no. 4, pp. 613-613 . https://doi.org/10.1038/s41593-020-00768-3
Nat Neurosci
In the version of this article initially published, author Thomas V. Wuttke’s affiliation was shown incorrectly. Dr. Wuttke is affiliated with University of Tübingen, Tübingen, Germany. The error has been corrected in the PDF and HTML versions of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4348877fb26994e655df991e32fe5bd3
https://doi.org/10.1038/s41593-020-00768-3
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Author Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types
Autor: Henner Koch, Jean Rossier, Gordon Fishell, Andreas S. Tolias, Sandra E. Dos Santos, Gábor Tamás, Kenta M. Hagihara, Juan Yuan, Pavel Němec, Tobias Bergmann, Boudewijn P. F. Lelieveldt, Pedro Larrañaga, Joshua R. Sanes, Hajime Hirase, William John Redmond, Huibert D. Mansvelder, Markus M. Hilscher, Homeira Moradi Chameh, Samuel Pontes, Jochen F. Staiger, Detlev Arendt, Marco Capogna, Keagan Dunville, Yong Liu, Natalia A. Goriounova, VS Bokharaie, Malte Kühnemund, Alok Nath Mohapatra, Christian Wozny, Irina Bystron, YoonJeung Chang, Michael Hawrylycz, Ed S. Lein, Peter Somogyi, Concha Bielza, Netanel Ofer, Ole Kiehn, Konstantin Khodosevich, Julio Martinez-Trujillo, Emma Louise Louth, Richárd Fiáth, Suzana Herculano-Houzel, Eric S. Kuebler, Maria Antonietta Tosches, Giorgio A. Ascoli, Hermany Munguba, Esther Serrano-Saiz, Javier DeFelipe, Oscar Marín, Angelica Foggetti, Rebecca D. Hodge, Vanessa Jane Hall, Jens Hjerling-Leffler, Josh Huang, Ann M. Clemens, Rafiq Huda, Richard H. Scheuermann, Argel Aguilar-Valles, Rafael Yuste, Onur Güntürkün, Christiaan P. J. de Kock, Thomas V. Wuttke, Ulrich Pfisterer, Xuefan Gao, Jan H. Lui, Nadia Aalling, Parviz Ghaderi, Miguel Turrero García, Moritz Helmstaedter, Rubén Armañanzas, Hongkui Zeng, Dirk Feldmeyer
Publikováno v: Nature Neuroscience
Yuste, R, Hawrylycz, M, Aalling, N, Aguilar-Valles, A, Arendt, D, Armañanzas, R, Ascoli, G A, Bielza, C, Bokharaie, V, Bergmann, T B, Bystron, I, Capogna, M, Chang, Y J, Clemens, A, de Kock, C P J, DeFelipe, J, Dos Santos, S E, Dunville, K, Feldmeyer, D, Fiáth, R, Fishell, G J, Foggetti, A, Gao, X, Ghaderi, P, Goriounova, N A, Güntürkün, O, Hagihara, K, Hall, V J, Helmstaedter, M, Herculano-Houzel, S, Hilscher, M M, Hirase, H, Hjerling-Leffler, J, Hodge, R, Huang, J, Huda, R, Khodosevich, K, Kiehn, O, Koch, H, Kuebler, E S, Kühnemund, M, Larrañaga, P, Lelieveldt, B, Louth, E L, Lui, J H, Mansvelder, H D, Marin, O, Martinez-Trujillo, J, Chameh, H M, Mohapatra, A N, Munguba, H, Nedergaard, M, Němec, P, Ofer, N, Pfisterer, U G, Pontes, S, Redmond, W, Rossier, J, Sanes, J R, Scheuermann, R H, Serrano-Saiz, E, Staiger, J F, Somogyi, P, Tamás, G, Tolias, A S, Tosches, M A, García, M T, Wozny, C, Wuttke, T V, Liu, Y, Yuan, J, Zeng, H & Lein, E 2021, ' Author Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types ', Nature Neuroscience, vol. 24, no. 4, pp. 612-612 . https://doi.org/10.1038/s41593-020-00779-0
To understand the function of cortical circuits, it is necessary to catalog their cellular diversity. Past attempts to do so using anatomical, physiological or molecular features of cortical cells have not resulted in a unified taxonomy of neuronal o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631ef9525e9489bcb009de0845b2f53f
http://europepmc.org/articles/PMC8012203
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SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues
Autor: Alex K. Shalek, Kun Zhang, Christopher W. Peterson, Orit Rosen, Alison Yu, Robert Lafyatis, Samuel W. Kazer, Oliver Eickelberg, Sarah A. Teichmann, Mauricio Rojas, Martijn C. Nawijn, Colin D. Bingle, Thu Elizabeth Duong, Manuel Garber, Magali Plaisant, Philana Ling Lin, Christine S. Falk, Jennifer P. Wang, Xin Sun, Hengqi Betty Zheng, G. James Gatter, Sarah K. Nyquist, Malte Kühnemund, Joachim L. Schultze, Mark A. Krasnow, Maarten van den Berge, Yan Xu, Samuel J. Allon, Daniel F. Dwyer, Peter Horvath, Benjamin Doran, Brian M. Lin, Herbert B. Schiller, Blake M. Hauser, Fabian J. Theis, Avrum Spira, Paul A. Reyfman, Hans-Peter Kiem, Shaina L. Carroll, Zhiru Guo, Douglas P. Shepherd, Michael von Papen, Ian M. Mbano, Michael Farzan, Daniel Lingwood, JoAnne L. Flynn, Christoph Muus, Dana Pe'er, Stephen R. Quake, Travis K. Hughes, Sarah M. Fortune, Sten Linnarson, Chase J. Taylor, Tanya M. Laidlaw, Emma L. Rawlins, Bonnie Berger, Ashraf S. Yousif, Joakim Lundeberg, Jeffrey A. Whitsett, Ian A. Glass, Delphine Gras, Max A. Seibold, Jay Rajagopal, Jared Feldman, Victor Tkachev, Benjamin E. Mead, Joseph E. Powell, Aviv Regev, Alasdair Leslie, Robert W. Finberg, Yuming Cao, Jennifer M.S. Sucre, Marko Vukovic, Scott B. Snapper, Vincent N. Miao, Naftali Kaminski, Laure-Emmanuelle Zaragosi, Caylin G. Winchell, Faith Taliaferro, Marko Nikolic, Ilias Angelidis, Leslie S. Kean, Lucrezia Colonna, Kathleen M. Buchheit, Aaron G. Schmidt, Ramnik J. Xavier, Tushar J. Desai, Marc H. Wadsworth, Joshua A. Boyce, Alexander M. Tsankov, Nora A. Barrett, Pascal Barbry, Muzlifah Haniffa, Heiko Adler, Alvis Brazma, Hannah P. Gideon, Meshal Ansari, Jason R. Spence, Avinash Waghray, Constantine N. Tzouanas, Jose Ordovas-Montanes, Jonathan A. Kropski, Nicholas E. Banovich, Purushothama Rao Tata, Kerstin B. Meyer, Christos Samakovlis, Haeock Lee, Carly G. K. Ziegler, Alexander V. Misharin, Deborah T. Hung, Sylvie Leroy, Julia Bals, Vanessa Mitsialis, Kourosh Saeb-Parsy
Publikováno v: Cell
Cell, 2020, 181 (5), pp.1016-1035.e19. ⟨10.1016/j.cell.2020.04.035⟩
Cell, Elsevier, 2020, 181 (5), pp.1016-1035.e19. ⟨10.1016/j.cell.2020.04.035⟩
Cell 181, 1016-1035 (2020)
Elsevier
Cell, 181(5), 1016-1035.e19. CELL PRESS
Summary There is pressing urgency to understand the pathogenesis of the severe acute respiratory syndrome coronavirus clade 2 (SARS-CoV-2), which causes the disease COVID-19. SARS-CoV-2 spike (S) protein binds angiotensin-converting enzyme 2 (ACE2),
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727543612f7db162539d6c42ca832836
https://doi.org/10.1016/j.cell.2020.04.035
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9
In situ detection of point mutations and targeted DNA sequencing using mobile phone microscopy (Conference Presentation)
Autor: Annika Ahlford, Evangelia Darai, Mats Nilsson, Qingshan Wei, Aydogan Ozcan, Derek Tseng, Yingjie Wang, Iván Hernández-Neuta, Zhao Yang, Malte Kühnemund
Publikováno v: Optics and Biophotonics in Low-Resource Settings IV.
KRAS mutation is a common point mutation which occurs in ~30% of all human cancers. Early assessment of KRAS mutation status is critical for prediction of clinical treatment outcomes. However, current diagnostic methods are based on either polymerase
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a330d5ac1b4668fcc73374d6591e422c
https://doi.org/10.1117/12.2289325
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Digital quantification of rolling circle amplified single DNA molecules in a resistive pulse sensing nanopore
Autor: Malte Kühnemund, Mats Nilsson
Publikováno v: Biosensors and Bioelectronics. 67:11-17
Novel portable, sensitive and selective DNA sensor methods for bio-sensing applications are required that can rival conventionally used non-portable and expensive fluorescence-based sensors. In this paper, rolling circle amplification (RCA) products
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a57b933e29d6d3b6f32f94c1b3d7d23
https://doi.org/10.1016/j.bios.2014.06.040
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