Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Malte Jensen"'
Autor:
Malte Jensen, Andreas Clemmensen, Jacob Gorm Hansen, Julie van Krimpen Mortensen, Emil N. Christensen, Andreas Kjaer, Rasmus Sejersten Ripa
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-8 (2024)
Abstract A pivotal animal model for development of anticancer molecules is mice with subcutaneous tumors, grown by injection of xenografted tumor cells, where micro-Computed Tomography (µCT) of the mice is used to analyze the efficacy of the antican
Externí odkaz:
https://doaj.org/article/a9b3ce13009b4075b1f60615e45c5447
Autor:
Shih-Cheng Huang, Anuj Pareek, Malte Jensen, Matthew P. Lungren, Serena Yeung, Akshay S. Chaudhari
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Advancements in deep learning and computer vision provide promising solutions for medical image analysis, potentially improving healthcare and patient outcomes. However, the prevailing paradigm of training deep learning models requires large
Externí odkaz:
https://doaj.org/article/9b6f3e412f324b4cbab8e2c3411223a5
Autor:
Malte Jensen, Simon Bentsen, Andreas Clemmensen, Jacob Kildevang Jensen, Johanne Madsen, Jonas Rossing, Anna Laier, Philip Hasbak, Andreas Kjaer, Rasmus Sejersten Ripa
Publikováno v:
EJNMMI Physics, Vol 9, Iss 1, Pp 1-18 (2022)
Abstract Background Myocardial perfusion imaging (MPI) using positron emission tomography (PET) tracers is an essential tool in investigating diseases and treatment responses in cardiology. 82Rubidium (82Rb)-PET imaging is advantageous for MPI due to
Externí odkaz:
https://doaj.org/article/d65f7d1787024831b6d5864709feb236
Autor:
Ane Beth Sloth, Babak Bakhshinejad, Malte Jensen, Camilla Stavnsbjerg, Mikkel Baldtzer Liisberg, Maria Rossing, Andreas Kjaer
Publikováno v:
Viruses, Vol 14, Iss 11, p 2402 (2022)
The principal presumption of phage display biopanning is that the naïve library contains an unbiased repertoire of peptides, and thus, the enriched variants derive from the affinity selection of an entirely random peptide pool. In the current study,
Externí odkaz:
https://doaj.org/article/fafcebfb51ba415e8d9afd18b55b987e
Autor:
Anne Kruse Hollensen, Henriette Sylvain Thomsen, Marta Lloret-Llinares, Andreas Bjerregaard Kamstrup, Jacob Malte Jensen, Majbritt Luckmann, Nanna Birkmose, Johan Palmfeldt, Torben Heick Jensen, Thomas B Hansen, Christian Kroun Damgaard
Publikováno v:
eLife, Vol 9 (2020)
Circular RNAs are important for many cellular processes but their mechanisms of action remain poorly understood. Here, we map circRNA inventories of mouse embryonic stem cells, neuronal progenitor cells and differentiated neurons and identify hundred
Externí odkaz:
https://doaj.org/article/b170dcfbda20479089e07cc9941f0b42
Autor:
Thomas B. Hansen, Torben Heick Jensen, Johan Palmfeldt, Jacob Malte Jensen, Marta Lloret-Llinares, Christian Kroun Damgaard, Nanna Birkmose, Anne Kruse Hollensen, Andreas Bjerregaard Kamstrup, Majbritt Luckmann, Henriette Sylvain Thomsen
Publikováno v:
eLife, Vol 9 (2020)
eLife
Hollensen, A K, Thomsen, H S, Lloret-Llinares, M, Kamstrup, A B, Jensen, J M, Luckmann, M, Birkmose, N, Palmfeldt, J, Jensen, T H, Hansen, T B & Damgaard, C K 2020, ' circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation ', eLife, vol. 9, e58478 . https://doi.org/10.7554/eLife.58478
eLife
Hollensen, A K, Thomsen, H S, Lloret-Llinares, M, Kamstrup, A B, Jensen, J M, Luckmann, M, Birkmose, N, Palmfeldt, J, Jensen, T H, Hansen, T B & Damgaard, C K 2020, ' circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation ', eLife, vol. 9, e58478 . https://doi.org/10.7554/eLife.58478
Circular RNAs (circRNAs) comprise a large class of conserved non-coding RNAs that regulate a number of biological processes, including transcription, alternative splicing, translation and mRNA decay. circRNAs are enriched in the brain and mammalian c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86cf2a50bb2ce0605e1e430222f4a3ad
https://doi.org/10.7554/elife.58478
https://doi.org/10.7554/elife.58478
Autor:
Johan Palmfeldt, Thomas B. Hansen, Torben Heick Jensen, Jacob Malte Jensen, Christian Kroun Damgaard, Andreas Bjerregaard Kamstrup, Nanna Birkmose, Marta Lloret-Llinares, Anne Kruse Hollensen, Majbritt Luckmann, Henriette Sylvain Thomsen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bf04c536796776e6fbf86029d9a46f0
https://doi.org/10.7554/elife.58478.sa2
https://doi.org/10.7554/elife.58478.sa2
Autor:
Chiranjeevi Bodda, Søren B. Jensen, Bao-Cun Zhang, Søren R. Paludan, Iver Nordentoft, Kasper L Jønsson, Stefanie Luecke, Chenglong Sun, Yujia Cai, Jacob Malte Jensen, Martin R. Jakobsen
Publikováno v:
Sun, C, Luecke, S, Bodda, C, Jønsson, K L, Cai, Y, Zhang, B C, Jensen, S B, Nordentoft, I, Jensen, J M, Jakobsen, M R & Paludan, S R 2019, ' Cellular Requirements for Sensing and Elimination of Incoming HSV-1 DNA and Capsids ', Journal of Interferon and Cytokine Research, vol. 39, no. 4, pp. 191-204 . https://doi.org/10.1089/jir.2018.0141
Incoming viruses challenge the cell with diverse foreign molecules, which need to be sensed quickly to initiate immune responses and to remove the viral components. In this study, we investigate the cellular requirements for sensing and degradation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e60bb670fb81d0b2940c5ce8550fef
https://pure.au.dk/portal/da/publications/cellular-requirements-for-sensing-and-elimination-of-incoming-hsv1-dna-and-capsids(29e121b6-2fba-443e-8ddd-35b46d17fb55).html
https://pure.au.dk/portal/da/publications/cellular-requirements-for-sensing-and-elimination-of-incoming-hsv1-dna-and-capsids(29e121b6-2fba-443e-8ddd-35b46d17fb55).html
Autor:
Kirstine Belling, Jacob Malte Jensen, Marlene Danner Dalgaard, Lise Aksglaede, Anders Juul, Kristian Almstrup, Ewa Rajpert-De Meyts, Mikkel H. Schierup, Søren Brunak, John E Nielsen, Niels E. Skakkebæk, Sofia B. Winge
Publikováno v:
Cell Death & Disease
Winge, S B, Dalgaard, M D, Belling, K G, Jensen, J M, Nielsen, J E, Aksglaede, L, Schierup, M H, Brunak, S, Skakkebæk, N E, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli-and Leydig cells article ', Cell Death & Disease, vol. 9, no. 6, 671 . https://doi.org/10.1038/s41419-018-0671-1
Winge, S B, Dalgaard, M D, Belling, K G, Jensen, J M, Nielsen, J E, Aksglaede, L, Schierup, M H, Brunak, S, Skakkebæk, N E, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli-and Leydig cells article ', Cell Death and Disease, vol. 9, no. 6, 586 . https://doi.org/10.1038/s41419-018-0671-1
Winge, S B, Dalgaard, M D, Belling, K G, Jensen, J M, Nielsen, J E, Aksglaede, L, Schierup, M H, Brunak, S, Skakkebæk, N E, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli-and Leydig cells ', Cell Death & Disease, vol. 9, no. 6, 586 . https://doi.org/10.1038/s41419-018-0671-1
Cell Death and Disease, Vol 9, Iss 6, Pp 1-14 (2018)
Winge, S B, Dalgaard, M D, Belling, K G, Jensen, J M, Nielsen, J E, Aksglaede, L, Schierup, M H, Brunak, S, Skakkebæk, N E, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli-and Leydig cells article ', Cell Death & Disease, vol. 9, no. 6, 671 . https://doi.org/10.1038/s41419-018-0671-1
Winge, S B, Dalgaard, M D, Belling, K G, Jensen, J M, Nielsen, J E, Aksglaede, L, Schierup, M H, Brunak, S, Skakkebæk, N E, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli-and Leydig cells article ', Cell Death and Disease, vol. 9, no. 6, 586 . https://doi.org/10.1038/s41419-018-0671-1
Winge, S B, Dalgaard, M D, Belling, K G, Jensen, J M, Nielsen, J E, Aksglaede, L, Schierup, M H, Brunak, S, Skakkebæk, N E, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli-and Leydig cells ', Cell Death & Disease, vol. 9, no. 6, 586 . https://doi.org/10.1038/s41419-018-0671-1
Cell Death and Disease, Vol 9, Iss 6, Pp 1-14 (2018)
The most common human sex chromosomal disorder is Klinefelter syndrome (KS; 47,XXY). Adult patients with KS display a diverse phenotype but are nearly always infertile, due to testicular degeneration at puberty. To identify mechanisms causing the sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b8c69bb7d0aa5f81a00da3ff83c4a5
http://europepmc.org/articles/PMC5964117
http://europepmc.org/articles/PMC5964117
Autor:
Jacob Malte Jensen, Ewa Rajpert-De Meyts, Marlene Danner Dalgaard, Mikkel H. Schierup, Niels Graem, Kristian Almstrup, Sofia B. Winge, Anders Juul
Publikováno v:
Winge, S B, Dalgaard, M D, Jensen, J M, Graem, N, Schierup, M H, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome profiling of fetal Klinefelter testis tissue reveals a possible involvement of long non-coding RNAs in gonocyte maturation ', Human Molecular Genetics, vol. 27, no. 3, ddx411 . https://doi.org/10.1093/hmg/ddx411
Winge, S B, Dalgaard, M D, Jensen, J M, Graem, N, Schierup, M H, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome profiling of fetal Klinefelter testis tissue reveals a possible involvement of long non-coding RNAs in gonocyte maturation ', Human Molecular Genetics, vol. 27, no. 3, pp. 430-439 . https://doi.org/10.1093/hmg/ddx411
Winge, S B, Dalgaard, M D, Jensen, J M, Graem, N, Schierup, M H, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome profiling of fetal Klinefelter testis tissue reveals a possible involvement of long non-coding RNAs in gonocyte maturation ', Human Molecular Genetics, vol. 27, no. 3, pp. 430-439 . https://doi.org/10.1093/hmg/ddx411
In humans, the most common sex chromosomal disorder is Klinefelter syndrome (KS), caused by the presence of one or more extra X-chromosomes. KS patients display a varying adult phenotype but usually present with azoospermia due to testicular degenera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e463efd17f07813a8155e424ec8b0512
https://orbit.dtu.dk/en/publications/7ac89668-80f2-4724-9e34-59fb36867346
https://orbit.dtu.dk/en/publications/7ac89668-80f2-4724-9e34-59fb36867346