Comparative analysis of oncolytic potential of vesicular stomatitis virus serotypes Indiana and New Jersey in cancer cell lines

Autor: A. S. Isaeva, N. O. Porozova, E. Idota, S. I. Volodina, A. N. Lukashev, A. S. Malogolovkin

Publikováno v: Сеченовский вестник, Vol 14, Iss 4, Pp 17-30 (2023)

Aim. Compare the lytic efficiency and the kinetics of accumulation of vesicular stomatitis virus serotypes Indiana (VSV-IND) and New Jersey (VSV-NJ) on cell lines of mouse melanoma B16F10, human hepatocellular carcinoma HepG2 and human mammary adenoc

Externí odkaz: https://doaj.org/article/fa61d642ddd94495b4eb7295342c971d

Optimization strategies and advances in the research and development of AAV‐based gene therapy to deliver large transgenes

Autor: Valeria V. Kolesnik, Ruslan F. Nurtdinov, Ezekiel Sola Oloruntimehin, Alexander V. Karabelsky, Alexander S. Malogolovkin

Publikováno v: Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)

Abstract Adeno‐associated virus (AAV)‐based therapies are recognized as one of the most potent next‐generation treatments for inherited and genetic diseases. However, several biological and technological aspects of AAV vectors remain a critical

Externí odkaz: https://doaj.org/article/5df796987ecc465eaa9030b1bc810ca7

Design of a Replicative-Competent MGF110 (1L-5-6L) Deleted African Swine Fever Virus (Genotype II)

Autor: Nefedeva Mariia V., Malogolovkin Alexander S., Titov Ilya A.

Publikováno v: Acta Veterinaria, Vol 73, Iss 1, Pp 13-21 (2023)

Viral individual genes functions and their role in the interaction with the host cells remain the main area in the study of African swine fever virus (ASFV) biology. The extreme heterogeneity of the ASFV makes it difficult to develop vaccines against

Externí odkaz: https://doaj.org/article/d21aaafb99324f9ba261c8019b986a2d

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Molecular and ultrastructural characteristics of virulent and attenuated vaccine strains of goose parvovirus LIV-22.

Autor: Oloruntimehin ES; Molecular Virology Laboratory, Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, First Moscow State Medical University (Sechenov University), Trubetskaya 8, 119048, Moscow, Russia., Volodina SI; Molecular Virology Laboratory, Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, First Moscow State Medical University (Sechenov University), Trubetskaya 8, 119048, Moscow, Russia., Patraman IV; Molecular Virology Laboratory, Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, First Moscow State Medical University (Sechenov University), Trubetskaya 8, 119048, Moscow, Russia., Nadtochey GA; Federal Research Center - All-Russian Research Institute of Experimental Veterinary Medicine named after K.I. Skrjabin and Y. R. Kovalenko of the Russian Academy of Sciences, Ryazanskiy pr. 24/1, 109428, Moscow, Russia., Malogolovkin AS; Molecular Virology Laboratory, Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, First Moscow State Medical University (Sechenov University), Trubetskaya 8, 119048, Moscow, Russia. Malogolovkin_a_s@staff.sechenov.ru.; Gene Therapy Department, Science Center for Translational Medicine, Sirius University of Science and Technology, Olimpiyskiy Ave, B.1, 354340, Sirius, Russia. Malogolovkin_a_s@staff.sechenov.ru.; Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, 169857, Singapore. Malogolovkin_a_s@staff.sechenov.ru.

Publikováno v: Archives of virology [Arch Virol] 2024 Dec 08; Vol. 170 (1), pp. 4. Date of Electronic Publication: 2024 Dec 08.