ENHANCED ANTI-TUMOR ACTIVITY OF CD19.CAR-NK CELLS BY INCORPORATING IL-27

Autor: Biggi, AFB, Silvestre, RN, Azevedo, JTC, Tirapelle, MC, Malmegrim, KCR, Figueiredo, ML, Covas, DT, Picanço-Castro, V

Publikováno v: In Hematology, Transfusion and Cell Therapy October 2023 45 Supplement 4:S534-S534

PROMOTER CHOICE: THE IDEAL PROMOTER TO DRIVE CHIMERIC ANTIGEN RECEPTOR (CAR) EXPRESSION IN NK CELLS

Autor: Silvestre, RN, Eitler, J, Azevedo, JTC, Malmegrim, KCR, Swiech, K, Covas, DT, Tonn, T, Picanço-Castro, V

Publikováno v: In Hematology, Transfusion and Cell Therapy October 2021 43 Supplement 1:S268-S269

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

IL-27-engineered CAR.19-NK-92 cells exhibit enhanced therapeutic efficacy.

Autor: Biggi AFB; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo, São Paulo, Brazil., Silvestre RN; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo, São Paulo, Brazil., Tirapelle MC; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo, São Paulo, Brazil., de Azevedo JTC; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo, São Paulo, Brazil; Department of Hemotherapy and Cellular Therapy, Hospital Israelita Albert Einstein, São Paulo, Brazil., García HDM; Universidade Estadual de Campinas, Instituto de Biologia, São Paulo, Brazil., Henrique Dos Santos M; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo, São Paulo, Brazil., de Lima SCG; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo, São Paulo, Brazil., de Souza LEB; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo, São Paulo, Brazil., Covas DT; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo, São Paulo, Brazil., Malmegrim KCR; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo, São Paulo, Brazil; Department of Clinical Analyses, Toxicology and Food Science, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil., Figueiredo ML; Department of Basic Medical Sciences, Purdue University, West Lafayette, Indiana, USA., Picanço-Castro V; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo, São Paulo, Brazil. Electronic address: virginia.picanco@hemocentro.fmrp.usp.br.

Publikováno v: Cytotherapy [Cytotherapy] 2024 Nov; Vol. 26 (11), pp. 1320-1330. Date of Electronic Publication: 2024 Jun 06.