A Clostridium difficile Cell Wall Glycopolymer Locus Influences Bacterial Shape, Polysaccharide Production and Virulence

Autor: Chu, Michele, Mallozzi, Michael J. G., Roxas, Bryan P., Bertolo, Lisa, Monteiro, Mario A., Agellon, Al, Viswanathan, V. K., Vedantam, Gayatri

Clostridium difficile is a diarrheagenic pathogen associated with significant mortality and morbidity. While its glucosylating toxins are primary virulence determinants, there is increasing appreciation of important roles for non-toxin factors in C.

Externí odkaz: http://hdl.handle.net/10150/622410
http://arizona.openrepository.com/arizona/handle/10150/622410

Surface-Layer Protein A (SlpA) Is a Major Contributor to Host-Cell Adherence of Clostridium difficile.

Autor: Merrigan, Michelle M., Venugopal, Anilrudh, Roxas, Jennifer L., Anwar, Farhan, Mallozzi, Michael J., Roxas, Bryan A. P., Gerding, Dale N., Viswanathan, V. K., Vedantam, Gayatri

Publikováno v: PLoS ONE; Nov2013, Vol. 8 Issue 11, p1-12, 12p

A Clostridium difficile Cell Wall Glycopolymer Locus Influences Bacterial Shape, Polysaccharide Production and Virulence.

Autor: Chu M; School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, United States of America., Mallozzi MJ; School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, United States of America., Roxas BP; School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, United States of America., Bertolo L; Department of Chemistry, University of Guelph, Guelph, Ontario, Canada., Monteiro MA; Department of Chemistry, University of Guelph, Guelph, Ontario, Canada., Agellon A; School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, United States of America., Viswanathan VK; School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, United States of America.; Department of Immunobiology, Bio5 Institute for Collaborative Research, University of Arizona, Tucson, Arizona, United States of America., Vedantam G; School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, United States of America.; Department of Immunobiology, Bio5 Institute for Collaborative Research, University of Arizona, Tucson, Arizona, United States of America.; Southern Arizona VA Healthcare System, Tucson, Arizona, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2016 Oct 14; Vol. 12 (10), pp. e1005946. Date of Electronic Publication: 2016 Oct 14 (Print Publication: 2016).