Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Mallory L Downie"'
Autor:
Patrick Hamilton, Kieran Blaikie, Stephen A Roberts, Matthew Gittins, Mallory L Downie, Sanjana Gupta, Catalin Voinescu, Durga Kanigicherla, Horia Stanescu, Robert Kleta, Paul Brenchley
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0281795 (2023)
BackgroundDespite MN being one of the most common causes of nephrotic syndrome worldwide, its biological and environmental determinants are poorly understood in large-part due to it being a rare disease. Making use of the UK Biobank, a unique resourc
Externí odkaz:
https://doaj.org/article/4f56f781985d4549bd09452989ed66ef
Autor:
Manel Adi, Faegheh Ghanbari, Mallory L Downie, Adriana Hung, Cassiane Robinson-Cohen, Despoina Manousaki
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 108:1442-1451
Context Observational studies investigating the role of vitamin D in renal function have yielded inconsistent results. Objective We tested whether 25-hydroxyvitamin D (25[OH]D) serum levels are associated with renal function, and inversely, whether a
Autor:
Mallory L. Downie, Sanjana Gupta, Melanie M. Y. Chan, Omid Sadeghi-Alavijeh, Jingjing Cao, Rulan S. Parekh, Carmen Bugarin Diz, Agnieszka Bierzynska, Adam P. Levine, Ruth J. Pepper, Horia Stanescu, Moin A. Saleem, Robert Kleta, Detlef Bockenhauer, Ania B. Koziell, Daniel P. Gale
Publikováno v:
Pediatric Nephrology. 38:1793-1800
Background Idiop athic nephrotic syndrome (INS) is classified in children according to response to initial corticosteroid therapy into steroid-sensitive (SSNS) and steroid-resistant nephrotic syndrome (SRNS), and in adults according to histology into
Autor:
Mallory L. Downie, Sanjana Gupta, Catalin Voinescu, Adam P. Levine, Omid Sadeghi-Alavijeh, Stephanie Dufek-Kamperis, Jingjing Cao, Martin Christian, Jameela A. Kari, Shenal Thalgahagoda, Randula Ranawaka, Asiri Abeyagunawardena, Rasheed Gbadegesin, Rulan Parekh, Robert Kleta, Detlef Bockenhauer, Horia C. Stanescu, Daniel P. Gale
Publikováno v:
Kidney International Reports.
Autor:
Mallory L Downie, Sanjana Gupta, Catalin Voinescu, Adam P Levine, Omid Sadeghi-Alavijeh, Stephanie Dufek-Kamperis, Jingjing Cao, Martin Christian, Jameela A Kari, Shenal Thalgahagoda, Randula Ranawaka, Asiri Abeyagunawardena, Rasheed Gbadegesin, Rulan Parekh, Robert Kleta, Detlef Bockenhauer, Horia C Stanescu, Daniel P Gale
BackgroundSteroid-sensitive nephrotic syndrome (SSNS) is the most common form of kidney disease in children worldwide. Genome-wide association studies (GWAS) have demonstrated association of SSNS with genetic variation at HLA-DQ/DR and have identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ced57abd04e3272e34ab41ce243692e0
https://doi.org/10.1101/2022.10.05.510923
https://doi.org/10.1101/2022.10.05.510923
Autor:
Chris Cheshire, Mallory L. Downie, Alvaro Madrid Aris, Steven Arora, Horia Stanescu, Christoph Licht, Lisa A. Robinson, Robert Kleta, Mehmet Tekman, Paul Brenchley, Sanjana Gupta, Detlef Bockenhauer, Ibrahim Al Attrach, Marina Munoz, Daniel P. Gale
Publikováno v:
Scientia
Downie, M L, Gupta, S, Tekman, M C, Cheshire, C, Arora, S, Licht, C, Robinson, L A, Munoz, M, Aris, A M, Al Attrach, I, Brenchley, P E, Gale, D P, Stanescu, H, Bockenhauer, D & Kleta, R 2021, ' Identification of a Locus on the X Chromosome Linked to Familial Membranous Nephropathy ', Kidney International Reports, vol. 6, no. 6, pp. 1669-1676 . https://doi.org/10.1016/j.ekir.2021.02.025, https://doi.org/10.1016/j.ekir.2021.02.025
Kidney International Reports, Vol 6, Iss 6, Pp 1669-1676 (2021)
Kidney International Reports
Downie, M L, Gupta, S, Tekman, M C, Cheshire, C, Arora, S, Licht, C, Robinson, L A, Munoz, M, Aris, A M, Al Attrach, I, Brenchley, P E, Gale, D P, Stanescu, H, Bockenhauer, D & Kleta, R 2021, ' Identification of a Locus on the X Chromosome Linked to Familial Membranous Nephropathy ', Kidney International Reports, vol. 6, no. 6, pp. 1669-1676 . https://doi.org/10.1016/j.ekir.2021.02.025, https://doi.org/10.1016/j.ekir.2021.02.025
Kidney International Reports, Vol 6, Iss 6, Pp 1669-1676 (2021)
Kidney International Reports
Introduction Membranous nephropathy (MN) is the most common cause of nephrotic syndrome (NS) in adults and is a leading cause of end-stage renal disease due to glomerulonephritis. Primary MN has a strong male predominance, accounting for approximatel
Autor:
R. Todd Alexander, Mallory L. Downie
Publikováno v:
Pediatric Nephrology. 37:707-718
The majority of calcium filtered by the glomerulus is reabsorbed along the nephron. Most is reabsorbed from the proximal tubule (> 60%) via a paracellular pathway composed of the tight junction proteins claudins-2 and -12, a process driven by sodium
Publikováno v:
Clinical Journal of the American Society of Nephrology. 16:620-630
The kidney tubules provide homeostasis by maintaining the external milieu that is critical for proper cellular function. Without homeostasis, there would be no heartbeat, no muscle movement, no thought, sensation, or emotion. The task is achieved by
Autor:
Daniel P. Gale, Stephanie Dufek-Kamperis, Mallory L. Downie, Robert Kleta, Detlef Bockenhauer
Publikováno v:
Dufek-Kamperis, S, Kleta, R, Bockenhauer, D, Gale, D & Downie, M L 2021, ' Novel insights in the genetics of steroid-sensitive nephrotic syndrome in childhood ', Pediatric Nephrology, vol. 36, no. 8, pp. 2165-2175 . https://doi.org/10.1007/s00467-020-04780-4
Steroid-sensitive nephrotic syndrome (SSNS) is the most common form of nephrotic syndrome in childhood and there is growing evidence that genetics play a role in the susceptibility for the disease. Familial clustering has been observed and has led to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9447938218c6c6b4b460ea5f54248c93
https://pure.au.dk/portal/da/publications/novel-insights-in-the-genetics-of-steroidsensitive-nephrotic-syndrome-in-childhood(8aad1a0b-ecba-48fd-a2e0-c1ef18b4a7e2).html
https://pure.au.dk/portal/da/publications/novel-insights-in-the-genetics-of-steroidsensitive-nephrotic-syndrome-in-childhood(8aad1a0b-ecba-48fd-a2e0-c1ef18b4a7e2).html
Autor:
Mallory L, Downie, R Todd, Alexander
Publikováno v:
Pediatric nephrology (Berlin, Germany). 37(4)
The majority of calcium filtered by the glomerulus is reabsorbed along the nephron. Most is reabsorbed from the proximal tubule (60%) via a paracellular pathway composed of the tight junction proteins claudins-2 and -12, a process driven by sodium an