Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mallory Gough"'
Publikováno v:
Biochemistry Research International, Vol 2011 (2011)
Alzheimer's disease is a neurodegenerative condition characterized by an accumulation of toxic amyloid beta- (A𝛽-)peptides in the brain causing progressive neuronal death. A𝛽-peptides are produced by aspartyl proteinase-mediated cleavage of the
Externí odkaz:
https://doaj.org/article/4815c007e5104391aab3397f5fd2365d
Publikováno v:
Int J MS Care
BACKGROUND Multiple sclerosis (MS) typically presents in young adulthood. Recent data show the highest prevalence of MS in people aged 55 to 64 years; however, there are limited studies of this population. METHODS Administrative US claims data from I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e403dc5cfe2a899f88cd416df37a3b30
https://europepmc.org/articles/PMC10010108/
https://europepmc.org/articles/PMC10010108/
Autor:
Todd Grinnell, Michael R. Sperling, Ladislav Pazdera, David Blum, Hailong Cheng, Jacqueline French, Mercedes P. Jacobson, Mallory Gough
Publikováno v:
Neurology. 86:1095-1102
Objective: To assess the efficacy and safety of eslicarbazepine acetate (ESL) monotherapy. Methods: This post hoc pooled analysis of 2 randomized double-blind studies (093-045 and -046) included adults with partial-onset seizures medically uncontroll
Publikováno v:
International Journal of Biochemistry Research & Review. 6:1-10
Epithelial to mesenchymal transition (EMT) confers migratory and dynamic properties on cells and, as such, plays a pivotal role in the development of metastatic, castration resistant prostate cancer. The amyloid precursor protein (APP), although most
Publikováno v:
Journal of Alzheimer's Disease. 43:1163-1168
Amyloid-β protein precursor (AβPP) proteolysis by β- and γ-secretases generates neurotoxic amyloid-β (Aβ)-peptides in Alzheimer's disease (AD). We have investigated the role of histidine residues within the extracellular E1 copper binding and A
Publikováno v:
Biochemistry Research International, Vol 2011 (2011)
Biochemistry Research International
Biochemistry Research International
Alzheimer's disease is a neurodegenerative condition characterized by an accumulation of toxic amyloid beta- (A-)peptides in the brain causing progressive neuronal death. A-peptides are produced by aspartyl proteinase-mediated cleavage of the larger
Publikováno v:
Biochemical and Biophysical Research Communications
Highlights • Copper levels are elevated in the tumour microenvironment. • APP mitigates copper-induced growth inhibition of DU145 prostate cancer (PCa) cells. • The APP intracellular domain is a prerequisite; soluble forms have no effect. • T