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pro vyhledávání: '"Mallori J Burse"'
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1, p e1003868 (2014)
The host protein CPSF6 possesses a domain that can interact with the HIV-1 capsid (CA) protein. CPSF6 has been implicated in regulating HIV-1 nuclear entry. However, its functional significance for HIV-1 replication has yet to be firmly established.
Externí odkaz:
https://doaj.org/article/6e5b92a7efa24ee8b0cf7ed55b8e2a6d
Autor:
Vaibhav Shah, Jiong Shi, Wade S. Blair, Hua Wu, Scott L. Butler, Upul D. Halambage, Jing Zhou, Mallori J. Burse, Christopher Aiken
Publikováno v:
Journal of Virology. 89:208-219
The HIV-1 capsid plays multiple roles in infection and is an emerging therapeutic target. The small-molecule HIV-1 inhibitor PF-3450074 (PF74) blocks HIV-1 at an early postentry stage by binding the viral capsid and interfering with its function. Sel
Autor:
Christopher Aiken, Masahiro Yamashita, Matthew S. Henning, Mallori J. Burse, Brittany N. Dubose
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1, p e1003868 (2014)
PLoS Pathogens
PLoS Pathogens
The host protein CPSF6 possesses a domain that can interact with the HIV-1 capsid (CA) protein. CPSF6 has been implicated in regulating HIV-1 nuclear entry. However, its functional significance for HIV-1 replication has yet to be firmly established.