Clinical and biomarker changes in premanifest Huntington disease show trial feasibility: A decade of the PREDICT-HD study

Autor: Paulsen, JS, Long, JD, Johnson, HJ, Aylward, EH, Ross, CA, Williams, JK, Nance, MA, Erwin, CJ, Westervelt, HJ, Harrington, DL, Bockholt, HJ, Zhang, Y, McCusker, EA, Chiu, EM, Panegyres, PK, Cross, S, Ryan, P, Epping, EA, Preston, J, Goh, A, Antonopoulos, S, Loi, S, Raymond, L, Decolongon, J, Fan, M, Coleman, A, Mallone, WM, Suter, G, Varvaris, M, Yoritomo, N, Griffith, J, Loy, C, Gunn, D, Guttman, M, Sheinberg, A, Law, A, Quaid, K, Wesson, M, Wojcieszek, J, Perlmutter, J, Barton, S, Smith, S, Barker, RA, Mason, S, Guzman, NV, Perlman, S, Clemente, B, Jones, R, Wood-Siverio, C, Factor, SA, Samii, A, Macaraeg, A, Lee, J, Tedesco, M, Maxwell, B, Kumar, R, Erickson, D, Nickels, B, Marshall, F, Chesire, A, Wodarski, M, Hickey, C, Geschwind, MD, Sha, S, Satris, G, Ahmed, A, Reece, C, Bura, A, Mourany, L, Pillai, J, Mazzoni, P, Marder, K, Wasserman, P, Craufurd, D, Bek, J, Howard, E, Warner, T, Burrows, M, Orth, M, Süßmuth, S, Barth, K, Trautmann, S, Schwenk, D, Eschenbach, C, Wheelock, V, Kjer, L, Martin, A, Farias, S, Miedzybrodzka, Z, Rae, D

Publikováno v: Paulsen, JS; Long, JD; Johnson, HJ; Aylward, EH; Ross, CA; Williams, JK; et al.(2014). Clinical and biomarker changes in premanifest Huntington disease show trial feasibility: A decade of the PREDICT-HD study. Frontiers in Aging Neuroscience, 6(APR). doi: 10.3389/fnagi.2014.00078. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2ms8c2jv

There is growing consensus that intervention and treatment of Huntington disease (HD) should occur at the earliest stage possible. Various early-intervention methods for this fatal neurodegenerative disease have been identified, but preventive clinic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::7c22eace304dad4db3ecfcceb9b14282
http://www.escholarship.org/uc/item/2ms8c2jv