Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Malliopoulou V"'
It has previously been shown that thyroid hormone can reverse cardiac remodeling in failing hearts by reducing myocardial wall stress due to the unique changes induced in cardiac myocyte shape. This effect may be of therapeutic relevance. Therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::be622e884f030ac4686e3ab5bc150b90
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3094819
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3094819
It has been previously reported that thyroid hormone receptor α1 (TRα1) is involved in the regulation of food intake and heart rhythm. Herein, we show that pharmacological inhibition of TRα1 by dronedarone, an amiodarone like compound (shown to an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::75a9b99e0c1e4601bc34ddcf288de4c5
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3095612
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3095612
Hyperthyroid hearts are shown to display a phenotype of cardioprotection against ischemic stress, but the underlying signaling mechanisms remain largely unknown. The present study investigated the possible relation of HSP70 to the thyroid hormone ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::f4f9d57fcbcbefb037620caa12a599ac
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3094888
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3094888
In the present study we investigated whether acute glucose administration could be protective against hypoxic stress. H9c2 cells were exposed to either 4.5 mM or 22 mM of glucose for 15,min and then were submitted to simulated ischemia. Cell death wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::837cd11eb0062d899b1a1806d37491ec
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3095309
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3095309
The present study investigated the tolerance of the isolated rat heart to ischemia - reperfusion after administration of trimetazidine (TMZ) at different experimental phases, as well as the possible involvement of p38 MAPK and JNKs in this response.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::a3fb90e7b91d01c4b6c53cd1d9454c61
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3093451
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3093451
Autor:
Pantos, C. Mourouzis, I. Saranteas, T. Paizis, I. Xinaris, C. Malliopoulou, V. Cokkinos, D.V.
There is accumulating evidence that thyroid hormone metabolism is altered after myocardial infarction (AMI) but its physiological relevance remains largely unknown. The present study investigated the possible role of thyroid hormone signaling in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::bd510961057223c872482881f3878f64
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3094735
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3094735
Hypothyroid heart displays a phenotype of cardioprotection against ischemia and this study investigated whether administration of dronedarone, an amiodarone-like compound that has been shown to preferentially antagonize thyroid hormone binding to thy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::fc7af7a08dfce7f2fee9068870df1ce3
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3093182
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3093182
Thyroid hormone has multiple effects on the cardiovascular system with important physiological consequences. Several genes that encode important regulatory and structural proteins in the heart have been shown to be thyroid hormone responsive. More no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::70bd5b14cfcfc1dc3d19ac94dfad9fbb
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3085419
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3085419
The present study investigated whether heat stress-induced cardioprotection involves alterations in the pattern of p38 mitogen activated protein kinase (p38MAPK) and c-Jun NH2-terminal kinase (JNK) activation during ischaemia-reperfusion in a model o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::87634efb926a1a89f97ddfbdcbeb9ce4
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3083582
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3083582
It has been recently shown that long-term thyroxine administration increases the tolerance of the heart to ischaemia. The present study investigated whether thyroxine induced cardioprotection involves alterations in the pattern of p38 mitogen activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::bf224c8d97ecfe91ec15532d0dbdfd60
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3082990
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3082990