Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mallinath B. Hadimani"'
Autor:
S. Bruce King, S. Tyler Aycock, Beth C. Holbrook, Emily Machiele, Mallinath B. Hadimani, Elene A Clemens, Matthew J. Jorgensen, Martha A. Alexander-Miller, Danielle Gries
Publikováno v:
Immunology. 153:357-367
Impaired immune responsiveness is a significant barrier to vaccination of neonates. By way of example, the low seroconversion observed following influenza vaccination has led to restriction of its use to infants over 6 months of age, leaving younger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025aeab92d3dbb7e2c9ed805c8de9b81
https://doi.org/10.1111/imm.12845
https://doi.org/10.1111/imm.12845
Autor:
Rajeswari Mukherjee, Ranjan Banerjee, Omar M. Aly, S. Bruce King, Mai E. Shoman, Mallinath B. Hadimani
Publikováno v:
Tetrahedron Letters. 56:5870-5873
Treatment of cyclopentanone and cyclobutanone-derived oximes with lead (IV) tetraacetate gives the bright blue acyloxy nitroso compounds, which upon basic hydrolysis yields the ring expansion product cyclic hydroxamic acids in 12-81% yield. Reactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2d38daae3c9dc54a29b6e603208928
https://doi.org/10.1016/j.tetlet.2015.09.002
https://doi.org/10.1016/j.tetlet.2015.09.002
Autor:
S. Tyler Aycock, Matthew J. Jorgensen, S. Bruce King, Ralph B. D'Agostino, Mallinath B. Hadimani, Beth C. Holbrook, Martha A. Alexander-Miller
Publikováno v:
Vaccine. 35(45)
Generation of a potent antibody response that can be sustained over time is highly challenging in young infants. Our previous studies using a nursery-reared nonhuman primate model identified R848 conjugated to inactivated influenza virus as a highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b76fb176ef68c6a9bb76615af93e425
https://pubmed.ncbi.nlm.nih.gov/28967521
https://pubmed.ncbi.nlm.nih.gov/28967521
Autor:
Mallinath B. Hadimani, Lance K. Blevins, S. Bruce King, Ralph B. D'Agostino, Martha A. Alexander-Miller, Jong R. Kim, Griffith D. Parks, Matthew J. Jorgensen, Beth C. Holbrook, Nancy D. Kock, S. Tyler Aycock
Influenza virus infection of neonates poses a major health concern, often resulting in severe disease and hospitalization. At present, vaccines for this at-risk population are lacking. Thus, development of an effective vaccine is an urgent need. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59c9460e87ed7196ebcb0c5f850c6f5
https://europepmc.org/articles/PMC4935603/
https://europepmc.org/articles/PMC4935603/
Autor:
Omar M. Aly, S. Bruce King, Ranjan Banerjee, Rajeswari Mukherjee, Mai E. Shoman, Mallinath B. Hadimani
Publikováno v:
ChemInform. 47
Treatment of cyclopentanone and cyclobutanone-derived oximes with lead (IV) tetraacetate gives the bright blue acyloxy nitroso compounds, which upon basic hydrolysis yields the ring expansion product cyclic hydroxamic acids in 12-81% yield. Reactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03f407104b165b8c9c35104f4e6caa73
https://doi.org/10.1002/chin.201615039
https://doi.org/10.1002/chin.201615039
Autor:
Christopher J. Jelinek, George R. Pettit, Justin K. Tidmore, Tracy E. Strecker, Madhavi Sriram, G.D. Kishore Kumar, Mallinath B. Hadimani, Mary Lynn Trawick, John J. Hall, David J. Chaplin, Kevin G. Pinney
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:5146-5149
A new trifluorinated amino-combretastatin analogue, ( Z) -2-(4′-methoxy-3′-aminophenyl)-1-(3,4,5-trifluorophenyl)ethene, prepared by chemical synthesis, was found to be a potent inhibitor of tubulin assembly (IC 50 = 2.9 μM), and cytotoxic again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5888082483e93431c2388d1229fecf9
https://doi.org/10.1016/j.bmcl.2008.07.070
https://doi.org/10.1016/j.bmcl.2008.07.070
Publikováno v:
Nanomedicine (London, England). 10(16)
Aims: To evaluate the use of glucosamine functionalized multiwalled carbon nanotubes (glyco-MWCNTs) for breast cancer targeting. Materials & methods: Two types of glucosamine functionalized MWCNTs were developed (covalently linked glucosamine and non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323fd9baf44b992d5fd252c7efc5bc92
https://pubmed.ncbi.nlm.nih.gov/26296098
https://pubmed.ncbi.nlm.nih.gov/26296098
Autor:
Anjan Ghatak, Ralph P. Mason, Li Liu, Tracy E. Strecker, Justin K. Tidmore, David J. Chaplin, Matthew T. MacDonough, Samuel O. Odutola, Li Li, Ramona Lopez, Morgan S. Cooper, Kevin G. Pinney, Mallinath B. Hadimani, Mary Lynn Trawick, Amanda K. Charlton-Sevcik
Publikováno v:
Cancer letters. 369(1)
This study describes the vascular disrupting ability and the mechanism of action of the indole-based tubulin-binding compound, OXi8006, and its water-soluble phosphate prodrug OXi8007. Treatment of rapidly proliferating human umbilical vein endotheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cab200720a170b2f7c02eb1565a1923
https://pubmed.ncbi.nlm.nih.gov/26325604
https://pubmed.ncbi.nlm.nih.gov/26325604
Autor:
George R. Pettit, Tracy E. Strecker, Ernest Hamel, Benson L. Nguyen, Mallinath B. Hadimani, Anjan Ghatak, Kevin G. Pinney, John J. Hall, Anupama Shirali, Ralph P. Mason, David J. Chaplin, Matthew T. MacDonough, Mary Lynn Trawick, Madhavi Sriram, Charles M. Garner, Raymond J. Kessler, Li Liu, Ramona Lopez
The natural products colchicine and combretastatin A-4 (CA4) are potent inhibitors of tubulin assembly, and they have inspired the design and synthesis of a large number of small-molecule, potential anticancer agents. The indole-based molecular scaff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c972c558adb693bd3abecabec987a420
https://europepmc.org/articles/PMC3985392/
https://europepmc.org/articles/PMC3985392/
Autor:
Randy Van der Ploeg, Paul Fernyhough, Victor Arballo, Meena K. Purohit, Nigel A. Calcutt, Chandrashaker Vanampally, Lakshmi P. Kotra, Mallinath B. Hadimani, Dwane Morrow, Katie E. Frizzi
Publikováno v:
Journal of medicinal chemistry. 56(12)
In diabetic patients, an early index of peripheral neuropathy is the slowing of conduction velocity in large myelinated neurons and a lack of understanding of the basic pathogenic mechanisms hindered therapeutics development. Racemic (R/S)-guaifenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd992d47946c7db9152244e8f859afd
https://pubmed.ncbi.nlm.nih.gov/23758573
https://pubmed.ncbi.nlm.nih.gov/23758573