Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Mallika Alvala"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1864-1871 (2019)
An efficient, simple, and metal-free synthetic approach for the N- and O-benzoylation of various amines/benzyl alcohols with pyridinium salts of phenacyl bromides is demonstrated to generate the corresponding amides and esters. This protocol facilita
Externí odkaz:
https://doaj.org/article/641bf9a7b1a9416e8bc3302c7ad3580b
Publikováno v:
Informatics in Medicine Unlocked, Vol 21, Iss , Pp 100411- (2020)
Galectin-3 is a carbohydrate-binding protein that plays a crucial role in cancer and fibrosis. Its inhibitors have largely evolved from naturally occurring saccharides to many synthetic forms with significantly improved affinity. However, there haven
Externí odkaz:
https://doaj.org/article/397046febab644e2bb306014021f30ca
Autor:
Kesari Lakshmi Manasa, Sravya Pujitha, Aaftaab Sethi, Mohammed Arifuddin, Mallika Alvala, Andrea Angeli, Claudiu T. Supuran
Publikováno v:
Metabolites, Vol 10, Iss 4, p 136 (2020)
A novel series of imidazo[2,1-b]thiazole-sulfonyl piperazine conjugates (9aa-ee) has been synthesized and evaluated for carbonic anhydrase (CA, EC 4.2.1.1) inhibitory potency against four isoforms: The cytosolic isozyme hCA I, II and trans-membrane t
Externí odkaz:
https://doaj.org/article/bf3ab3d477694e798e87bae8a0881610
Autor:
Srinivas Bandaru, Mallika Alvala, Anuraj Nayarisseri, Saphy Sharda, Himshikha Goud, Hema Prasad Mundluru, Sanjeev Kumar Singh
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186666 (2017)
The natural variant C491T (rs1800088) in ADRB2 gene substitutes Threonine to Isoleucine at 164th position in β2AR and results in receptor sequestration and altered binding of agonists. Present investigation pursues to identify the effect of T164I va
Externí odkaz:
https://doaj.org/article/2d91bf0c1cd942999b728772a1be1c2a
Akademický článek
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Autor:
Mallika Alvala, Aaftaab Sethi
Publikováno v:
Letters in Organic Chemistry. 20:585-595
Abstract: A series of pyranopyrazoles were synthesized via a one-pot four-component approach. The reaction was catalyzed by a β-CD/Yb(OTf)3 dual catalytic system. The protocol demonstrated offers several advantages such as short reaction times, exce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18016a514a52625bfd6b97f888f95331
https://doi.org/10.2174/1570178620666221122121021
https://doi.org/10.2174/1570178620666221122121021
Autor:
Kesari Lakshmi Manasa, Mallika Alvala, Mohd Aslam Saifi, Yellaiah Tangella, Chandraiah Godugu
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 19:1935-1948
Background: The synthesis of novel heterocyclic scaffolds with amide functionality is a key research area due to their plethora of medicinal applications. The present study aims to explore the synthesis of new cinnamido linked quinazolinone congeners
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f361459f137856a7a0c314685b29960e
https://doi.org/10.2174/1871520619666190906162537
https://doi.org/10.2174/1871520619666190906162537
Publikováno v:
RSC Advances. 10:29873-29884
The Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) has been rapidly transmitting and leaving its footprints across the globe. Stringent measures like complete lockdown and extensive testing have been employed by many countries to slow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f99a4d0d047e38583dc583923c9b3316
https://doi.org/10.1039/d0ra04795c
https://doi.org/10.1039/d0ra04795c
Autor:
Estari Mamidala, Mallika Alvala, Nerella Sridhar Goud, Swapna Gurrapu, Aaftaab Sethi, Komal Daipule
Publikováno v:
Journal of Heterocyclic Chemistry. 57:774-790
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b818012f56bca64a83e7f1f57d1c0f5d
https://doi.org/10.1002/jhet.3819
https://doi.org/10.1002/jhet.3819
Autor:
Aaftaab Sethi, Sarvesh Mehta, Yashaswi Pathak, U. Deva Priyakumar, Siddhartha Laghuvarapu, Mallika Alvala
Publikováno v:
Chemical Science
In drug discovery applications, high throughput virtual screening exercises are routinely performed to determine an initial set of candidate molecules referred to as “hits”. In such an experiment, each molecule from a large small-molecule drug li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43239745b2854bc285688c76c1a4a6b7
https://doi.org/10.33774/chemrxiv-2021-nr0vn-v2
https://doi.org/10.33774/chemrxiv-2021-nr0vn-v2
