Novel sulfamethoxazole and 1-(2-fluorophenyl) piperazine derivatives as potential apoptotic and antiproliferative agents by inhibition of BCL2; design, synthesis, biological evaluation, and docking studies.

Autor: Vadabingi N; Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh India., Mallepogu V; Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh 517502 India., Mallapu RE; Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh India., Pasala C; Bioinformatics Centre, Department of Bioinformatics, SVIMS University, Tirupati, Andhra Pradesh India., Poreddy S; Department of Chemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh India., Bellala P; Department of Chemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh India., Amineni U; Bioinformatics Centre, Department of Bioinformatics, SVIMS University, Tirupati, Andhra Pradesh India., Cirandur SR; Department of Chemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh India., Meriga B; Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh 517502 India.

Publikováno v: 3 Biotech [3 Biotech] 2024 Nov; Vol. 14 (11), pp. 269. Date of Electronic Publication: 2024 Oct 15.