Posttranslationally modified self-peptides promote hypertension in mouse models.

Autor: Bloodworth N; Division of Clinical Pharmacology, Department of Medicine., Chen W; Division of Clinical Pharmacology, Department of Medicine., Hunter K; Division of Clinical Pharmacology, Department of Medicine., Patrick D; Division of Clinical Pharmacology, Department of Medicine., Palubinsky A; Department of Medicine, and., Phillips E; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Australia.; Center for Drug Safety and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Roeth D; Department of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, California, USA., Kalkum M; Department of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, California, USA., Mallal S; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Australia., Davies S; Division of Clinical Pharmacology, Department of Medicine., Ao M; Division of Clinical Pharmacology, Department of Medicine., Moretti R; Center for Structural Biology, and., Meiler J; Center for Structural Biology, and.; Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA.; Institute for Drug Discovery, Universität Leipzig Medical School, Leipzig, Germany., Harrison DG; Division of Clinical Pharmacology, Department of Medicine.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2024 Aug 15; Vol. 134 (16). Date of Electronic Publication: 2024 Aug 15.

Single-cell Analysis of Subcutaneous Fat Reveals Pro-fibrotic Cells that Correlate with Visceral Adiposity in HIV.

Autor: Bailin SS; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Gabriel CL; Department of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, Nashville, Tennessee, USA., Gangula RD; Tennessee Center for AIDS Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Hannah L; Department of Medicine, Division of Diabetes, Endocrinology, and Metabolism, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Nair S; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Carr JJ; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Terry JG; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Silver HJ; Department of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, Nashville, Tennessee, USA.; Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, USA., Simmons JD; Tennessee Center for AIDS Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Mashayekhi M; Department of Medicine, Division of Diabetes, Endocrinology, and Metabolism, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Kalams SA; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Tennessee Center for AIDS Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Center for Translational Immunology and Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Mallal S; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Tennessee Center for AIDS Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Center for Translational Immunology and Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Insitute for Immunology and Infectious Diseases, Murdoch University, Perth, WA, Australia.; Vanderbilt Technologies for Advanced Genomics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Kropski JA; Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, USA.; Department of Medicine, Division of Allergy and Pulmonology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Deparment of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA., Wanjalla CN; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Center for Translational Immunology and Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Koethe JR; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, USA.; Center for Translational Immunology and Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Publikováno v: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2024 May 31. Date of Electronic Publication: 2024 May 31.

Updates in SJS/TEN: collaboration, innovation, and community.

Autor: Marks ME; Center for Drug Interactions and Immunology, Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States., Botta RK; Center for Drug Interactions and Immunology, Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States., Abe R; Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan., Beachkofsky TM; Departments of Dermatology and Medicine, Uniformed Services University, Bethesda, MD, United States., Boothman I; The SFI Centre for Research Training in Genomics Data Science, Dublin, Ireland., Carleton BC; Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia and the British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada., Chung WH; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan., Cibotti RR; National Institute of Arthritis and Musculoskeletal and Skin (NIAMS), National Institutes of Health (NIH), Bethesda, MD, United States., Dodiuk-Gad RP; Department of Dermatology, Emek Medical Center, Afula, Israel.; Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada.; Department of Dermatology, Bruce Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa, Israel., Grimstein C; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States., Hasegawa A; Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan., Hoofnagle JH; Liver Disease Research Branch, Division of Digestive Diseases and Nutrition of NIDDK, National Institutes of Health (NIH), Bethesda, MD, United States., Hung SI; Cancer Vaccine and Immune Cell Therapy Core Laboratory, Department of Medical Research, Chang Gung Memorial Hospital, Taoyuan, Taiwan., Kaffenberger B; Department of Dermatology, Ohio State University Wexner Medical Center, Columbus, OH, United States., Kroshinsky D; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Lehloenya RJ; Division of Dermatology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Martin-Pozo M; Center for Drug Interactions and Immunology, Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States., Micheletti RG; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Mockenhaupt M; Dokumentationszentrum schwerer Hautreaktionen (dZh), Department of Dermatology, Medical Center and Medical Faculty, University of Freiburg, Freiburg, Germany., Nagao K; National Institute of Arthritis and Musculoskeletal and Skin (NIAMS), National Institutes of Health (NIH), Bethesda, MD, United States., Pakala S; Center for Drug Interactions and Immunology, Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States., Palubinsky A; Center for Drug Interactions and Immunology, Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States., Pasieka HB; Departments of Dermatology and Medicine, Uniformed Services University, Bethesda, MD, United States.; The Burn Center, MedStar Washington Hospital Center, Washington, D.C., DC, United States.; Department of Dermatology, MedStar Health/Georgetown University, Washington, D.C., DC, United States., Peter J; Division of Allergy and Clinical Immunology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Pirmohamed M; Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, United Kingdom., Reyes M; Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD, United States., Saeed HN; Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United States., Shupp J; Department of Surgery, Plastic and Reconstructive Surgery, Biochemistry, and Molecular and Cellular Biology, MedStar Washington Hospital Center, Georgetown University School of Medicine, Washington, D.C., DC, United States., Sukasem C; Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand., Syu JY; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Ueta M; Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan., Zhou L; Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Chang WC; Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia and the British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada., Becker P; Division of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Disease, Bethesda, MD, United States., Bellon T; Drug Hypersensitivity Laboratory, La Paz Health Research Institute (IdiPAZ), Madrid, Spain., Bonnet K; Department of Psychology, Vanderbilt University, Nashville, TN, United States., Cavalleri G; The SFI Centre for Research Training in Genomics Data Science, Dublin, Ireland., Chodosh J; University of New Mexico School of Medicine, Albuquerque, NM, United States., Dewan AK; Department of Dermatology, Vanderbilt University Medical Center, Nashville, TN, United States., Dominguez A; Department of Dermatology and Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States., Dong X; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Ezhkova E; Department of Cell, Developmental, and Regenerative Biology and Dermatology, Black Family Stem Cell Institute, Mount Sinai School of Medicine, New York, NY, United States., Fuchs E; Department of Obstetrics and Gynecology, University of Washington, Seattle, WA, United States., Goldman J; Division of Pediatric Infectious Diseases and Clinical Pharmacology, Children's Mercy, Kansas City, MO, United States., Himed S; College of Medicine, University of Cincinnati, Cincinnati, OH, United States., Mallal S; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States., Markova A; Department of Dermatology, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, NY, United States., McCawley K; Stevens-Johnson Syndrome Foundation, Westminster, CO, United States., Norton AE; Division of Pediatric Allergy, Immunology, and Pulmonary Medicine, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, United States., Ostrov D; Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, United States., Phan M; Division of Pharmacovigilance-I, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States., Sanford A; Division of Trauma, Surgical Critical Care, and Burns, Loyola University Medical Center, Chicago, IL, United States., Schlundt D; Department of Psychology, Vanderbilt University, Nashville, TN, United States., Schneider D; Department of Psychiatry and Surgery, MedStar Washington Hospital Center, Georgetown University School of Medicine, Washington, D.C., DC, United States., Shear N; Department of Dermatology, Emek Medical Center, Afula, Israel., Shinkai K; Department of Dermatology, University of California, San Francisco, San Francisco, CA, United States., Tkaczyk E; Department of Veterans Affairs, Vanderbilt Dermatology Translational Research Clinic (VDTRC.org), Nashville, TN, United States., Trubiano JA; Department of Infectious Diseases and Medicine, Austin Health, University of Melbourne, Melbourne, VIC, Australia., Volpi S; National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH), Bethesda, MD, United States., Bouchard CS; Department of Opthalmology, Loyola University Medical Center, Chicago, IL, United States., Divito SJ; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Phillips EJ; Center for Drug Interactions and Immunology, Division of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.

Publikováno v: Frontiers in medicine [Front Med (Lausanne)] 2023 Oct 11; Vol. 10, pp. 1213889. Date of Electronic Publication: 2023 Oct 11 (Print Publication: 2023).

Author Correction: Africa-specific human genetic variation near CHD1L associates with HIV-1 load.

Autor: McLaren PJ; Sexually Transmitted and Blood-Borne Infections Division at JC Wilt Infectious Diseases Research Centre, National Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada. paul.mclaren@phac-aspc.gc.ca.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada. paul.mclaren@phac-aspc.gc.ca., Porreca I; Wellcome Trust Sanger Institute, Hinxton, UK., Iaconis G; Department of Medicine, University of Cambridge, Cambridge, UK., Mok HP; Department of Medicine, University of Cambridge, Cambridge, UK., Mukhopadhyay S; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK., Karakoc E; Wellcome Trust Sanger Institute, Hinxton, UK., Cristinelli S; Institute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Pomilla C; Wellcome Trust Sanger Institute, Hinxton, UK., Bartha I; Global Health Institute, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Thorball CW; Global Health Institute, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Precision Medicine Unit, Biomedical Data Science Center, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland., Tough RH; Sexually Transmitted and Blood-Borne Infections Division at JC Wilt Infectious Diseases Research Centre, National Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada., Angelino P; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Kiar CS; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK., Carstensen T; Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Medicine, University of Cambridge, Cambridge, UK., Fatumo S; The African Computational Genomics (TACG) Research Group, MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.; Department of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK., Porter T; Wellcome Trust Sanger Institute, Hinxton, UK., Jarvis I; Department of Medicine, University of Cambridge, Cambridge, UK., Skarnes WC; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Bassett A; Wellcome Trust Sanger Institute, Hinxton, UK., DeGorter MK; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Sathya Moorthy MP; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Tuff JF; Sexually Transmitted and Blood-Borne Infections Division at JC Wilt Infectious Diseases Research Centre, National Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada., Kim EY; Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Walter M; Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Simons LM; Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Bashirova A; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Buchbinder S; Bridge HIV, San Francisco Department of Public Health, San Francisco, CA, USA., Carrington M; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.; Ragon Institute of MGH, MIT and Harvard, Boston, MA, USA., Cossarizza A; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy., De Luca A; University Division of Infectious Diseases, Siena University Hospital, Siena, Italy.; Department of Medical Biotechnologies, University of Siena, Siena, Italy., Goedert JJ; Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Goldstein DB; Institute for Genomic Medicine, Columbia University, New York, NY, USA., Haas DW; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Herbeck JT; Department of Global Health, University of Washington, Seattle, WA, USA., Johnson EO; GenOmics and Translational Research Center and Fellow Program, RTI International, Research Triangle Park, NC, USA., Kaleebu P; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda.; London School of Hygiene and Tropical Medicine, London, UK., Kilembe W; Center for Family Health Research-Zambia, Lusaka, Zambia., Kirk GD; Department of Epidemiology, Johns Hopkins University, Baltimore, MD, USA., Kootstra NA; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Kral AH; Community Health Research Division, RTI International, Berkeley, CA, USA., Lambotte O; Université Paris Saclay, Inserm UMR1184, CEA, Le Kremlin-Bicêtre, France.; APHP, Department of Clinical Immunology, Bicêtre Hospital, Le Kremlin-Bicêtre, France., Luo M; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.; Vaccine and Therapeutics Laboratory, Medical and Scientific Affairs, National Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada., Mallal S; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.; Institute for Immunology & Infectious Diseases, Murdoch University, Perth, Western Australia, Australia., Martinez-Picado J; University of Vic-Central University of Catalonia, Vic, Spain.; IrsiCaixa AIDS Research Institute, Badalona, Spain.; Catalan Institution for Research and Advanced Studies, Barcelona, Spain.; CIBERINFEC, Instituto de Salud Carlos III, Madrid, Spain., Meyer L; INSERM U1018, Université Paris-Saclay, Le Kremlin Bicêtre, France.; AP-HP, Hôpital de Bicêtre, Département d'Épidémiologie, Le Kremlin Bicêtre, France., Miro JM; CIBERINFEC, Instituto de Salud Carlos III, Madrid, Spain.; Infectious Diseases Service, Hospital Clinic-Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain., Moodley P; National Health Laboratory Service, South Africa and University of KwaZulu-Natal, Durban, South Africa., Motala AA; Department of Diabetes and Endocrinology, School of Clinical Medicine, University of KwaZulu-Natal, Durban, South Africa., Mullins JI; Department of Microbiology, University of Washington, Seattle, WA, USA., Nam K; Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Obel N; Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Pirie F; Department of Diabetes and Endocrinology, School of Clinical Medicine, University of KwaZulu-Natal, Durban, South Africa., Plummer FA; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada., Poli G; Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy.; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy., Price MA; International AIDS Vaccine Initiative, New York, NY, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA., Rauch A; Department of Infectious Diseases, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Theodorou I; Laboratoire d'Immunologie, Hôpital Robert Debré Paris, Paris, France., Trkola A; Institute of Medical Virology, University of Zurich, Zurich, Switzerland., Walker BD; Ragon Institute of MGH, MIT and Harvard, Boston, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Winkler CA; Basic Research Laboratory, Molecular Genetic Epidemiology Section, Frederick National Laboratory for Cancer Research and Cancer Innovative Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA., Zagury JF; Laboratoire Génomique, Bioinformatique et Chimie Moléculaire, EA7528, Conservatoire National des Arts et Métiers, HESAM Université, Paris, France., Montgomery SB; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Ciuffi A; Institute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Hultquist JF; Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Wolinsky SM; Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Dougan G; Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Medicine, University of Cambridge, Cambridge, UK., Lever AML; Department of Medicine, University of Cambridge, Cambridge, UK.; Department of Medicine, National University of Singapore, Singapore, Singapore., Gurdasani D; Queen Mary University of London, London, UK.; Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia., Groom H; Department of Medicine, University of Cambridge, Cambridge, UK., Sandhu MS; Department of Epidemiology & Biostatistics, School of Public Health, Imperial College London, London, UK. m.sandhu@imperial.ac.uk.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK. m.sandhu@imperial.ac.uk.; Omnigen Biodata, Cambridge, UK. m.sandhu@imperial.ac.uk., Fellay J; Global Health Institute, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. jacques.fellay@epfl.ch.; Swiss Institute of Bioinformatics, Lausanne, Switzerland. jacques.fellay@epfl.ch.; Precision Medicine Unit, Biomedical Data Science Center, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland. jacques.fellay@epfl.ch.

Publikováno v: Nature [Nature] 2023 Sep; Vol. 621 (7979), pp. E42.

Africa-specific human genetic variation near CHD1L associates with HIV-1 load.

Autor: McLaren PJ; Sexually Transmitted and Blood-Borne Infections Division at JC Wilt Infectious Diseases Research Centre, National Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada. paul.mclaren@phac-aspc.gc.ca.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada. paul.mclaren@phac-aspc.gc.ca., Porreca I; Wellcome Trust Sanger Institute, Hinxton, UK., Iaconis G; Department of Medicine, University of Cambridge, Cambridge, UK., Mok HP; Department of Medicine, University of Cambridge, Cambridge, UK., Mukhopadhyay S; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK., Karakoc E; Wellcome Trust Sanger Institute, Hinxton, UK., Cristinelli S; Institute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Pomilla C; Wellcome Trust Sanger Institute, Hinxton, UK., Bartha I; Global Health Institute, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Thorball CW; Global Health Institute, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Precision Medicine Unit, Biomedical Data Science Center, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland., Tough RH; Sexually Transmitted and Blood-Borne Infections Division at JC Wilt Infectious Diseases Research Centre, National Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada., Angelino P; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Kiar CS; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK., Carstensen T; Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Medicine, University of Cambridge, Cambridge, UK., Fatumo S; The African Computational Genomics (TACG) Research Group, MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.; Department of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK., Porter T; Wellcome Trust Sanger Institute, Hinxton, UK., Jarvis I; Department of Medicine, University of Cambridge, Cambridge, UK., Skarnes WC; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Bassett A; Wellcome Trust Sanger Institute, Hinxton, UK., DeGorter MK; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Sathya Moorthy MP; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Tuff JF; Sexually Transmitted and Blood-Borne Infections Division at JC Wilt Infectious Diseases Research Centre, National Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada., Kim EY; Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Walter M; Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Simons LM; Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Bashirova A; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Buchbinder S; Bridge HIV, San Francisco Department of Public Health, San Francisco, CA, USA., Carrington M; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.; Ragon Institute of MGH, MIT and Harvard, Boston, MA, USA., Cossarizza A; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy., De Luca A; University Division of Infectious Diseases, Siena University Hospital, Siena, Italy.; Department of Medical Biotechnologies, University of Siena, Siena, Italy., Goedert JJ; Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Goldstein DB; Institute for Genomic Medicine, Columbia University, New York, NY, USA., Haas DW; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Herbeck JT; Department of Global Health, University of Washington, Seattle, WA, USA., Johnson EO; GenOmics and Translational Research Center and Fellow Program, RTI International, Research Triangle Park, NC, USA., Kaleebu P; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine, Uganda Research Unit, Entebbe, Uganda.; London School of Hygiene and Tropical Medicine, London, UK., Kilembe W; Center for Family Health Research-Zambia, Lusaka, Zambia., Kirk GD; Department of Epidemiology, Johns Hopkins University, Baltimore, MD, USA., Kootstra NA; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Kral AH; Community Health Research Division, RTI International, Berkeley, CA, USA., Lambotte O; Université Paris Saclay, Inserm UMR1184, CEA, Le Kremlin-Bicêtre, France.; APHP, Department of Clinical Immunology, Bicêtre Hospital, Le Kremlin-Bicêtre, France., Luo M; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.; Vaccine and Therapeutics Laboratory, Medical and Scientific Affairs, National Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada., Mallal S; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.; Institute for Immunology & Infectious Diseases, Murdoch University, Perth, Western Australia, Australia., Martinez-Picado J; University of Vic-Central University of Catalonia, Vic, Spain.; IrsiCaixa AIDS Research Institute, Badalona, Spain.; Catalan Institution for Research and Advanced Studies, Barcelona, Spain.; CIBERINFEC, Instituto de Salud Carlos III, Madrid, Spain., Meyer L; INSERM U1018, Université Paris-Saclay, Le Kremlin Bicêtre, France.; AP-HP, Hôpital de Bicêtre, Département d'Épidémiologie, Le Kremlin Bicêtre, France., Miro JM; CIBERINFEC, Instituto de Salud Carlos III, Madrid, Spain.; Infectious Diseases Service, Hospital Clinic-Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain., Moodley P; National Health Laboratory Service, South Africa and University of KwaZulu-Natal, Durban, South Africa., Motala AA; Department of Diabetes and Endocrinology, School of Clinical Medicine, University of KwaZulu-Natal, Durban, South Africa., Mullins JI; Department of Microbiology, University of Washington, Seattle, WA, USA., Nam K; Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Obel N; Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Pirie F; Department of Diabetes and Endocrinology, School of Clinical Medicine, University of KwaZulu-Natal, Durban, South Africa., Plummer FA; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada., Poli G; Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy.; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy., Price MA; International AIDS Vaccine Initiative, New York, NY, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA., Rauch A; Department of Infectious Diseases, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Theodorou I; Laboratoire d'Immunologie, Hôpital Robert Debré Paris, Paris, France., Trkola A; Institute of Medical Virology, University of Zurich, Zurich, Switzerland., Walker BD; Ragon Institute of MGH, MIT and Harvard, Boston, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Winkler CA; Basic Research Laboratory, Molecular Genetic Epidemiology Section, Frederick National Laboratory for Cancer Research and Cancer Innovative Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA., Zagury JF; Laboratoire Génomique, Bioinformatique et Chimie Moléculaire, EA7528, Conservatoire National des Arts et Métiers, HESAM Université, Paris, France., Montgomery SB; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Ciuffi A; Institute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Hultquist JF; Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Wolinsky SM; Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Dougan G; Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Medicine, University of Cambridge, Cambridge, UK., Lever AML; Department of Medicine, University of Cambridge, Cambridge, UK.; Department of Medicine, National University of Singapore, Singapore, Singapore., Gurdasani D; Queen Mary University of London, London, UK.; Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia., Groom H; Department of Medicine, University of Cambridge, Cambridge, UK., Sandhu MS; Department of Epidemiology & Biostatistics, School of Public Health, Imperial College London, London, UK. m.sandhu@imperial.ac.uk.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK. m.sandhu@imperial.ac.uk.; Omnigen Biodata, Cambridge, UK. m.sandhu@imperial.ac.uk., Fellay J; Global Health Institute, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. jacques.fellay@epfl.ch.; Swiss Institute of Bioinformatics, Lausanne, Switzerland. jacques.fellay@epfl.ch.; Precision Medicine Unit, Biomedical Data Science Center, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland. jacques.fellay@epfl.ch.

Publikováno v: Nature [Nature] 2023 Aug; Vol. 620 (7976), pp. 1025-1030. Date of Electronic Publication: 2023 Aug 02.