Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Malkanthi K, Karunananda"'
Autor:
Hui-Qi Ni, Malkanthi K. Karunananda, Tian Zeng, Shenghua Yang, Zhen Liu, K.N. Houk, Peng Liu, Keary M. Engle
Publikováno v:
Journal of the American Chemical Society.
Multi-step organic synthesis enables conversion of simple chemical feedstocks into a more structurally complex product that serves a particular function. The target compound is forged over several steps, with concomitant generation of byproducts in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41f6270718ba54b5ffc9d5a460a0283
https://doi.org/10.1021/jacs.3c03274
https://doi.org/10.1021/jacs.3c03274
Autor:
Roman Kleinmans, Keary M. Engle, Steven R. Wisniewski, Zi-Qi Li, Van T. Tran, Joseph Derosa, Omar Apolinar, Malkanthi K. Karunananda
Publikováno v:
Organic Letters. 23:5311-5316
A nickel-catalyzed 1,2-diarylation of alkenyl ketones with aryl iodides and arylboronic esters is reported. Ketones with a variety of substituents serve as effective directing groups, offering high levels of regiocontrol. A representative product is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebca951fb66e6421e3f06b740bc885d4
https://doi.org/10.1021/acs.orglett.1c01447
https://doi.org/10.1021/acs.orglett.1c01447
Autor:
Malkanthi K. Karunananda, Mingyu Liu, Keary M. Engle, Donna G. Blackmond, Nhi Nguyen, Rei Matsuura
Publikováno v:
ACS Catalysis. 11:4239-4246
Pd(II)-catalyzed E/Z isomerization of alkenes is a common process-yet its mechanism remains largely uncharacterized, particularly with non-conjugated alkenes. In this work, the mechanism of Pd(II)-catalyzed E/Z isomerization of unactivated olefins co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c5f9f8e85bf3b39078c67a6ce1a01b4
https://doi.org/10.1021/acscatal.1c00783
https://doi.org/10.1021/acscatal.1c00783
Autor:
Rei, Matsuura, Malkanthi K, Karunananda, Mingyu, Liu, Nhi, Nguyen, Donna G, Blackmond, Keary M, Engle
Publikováno v:
ACS Catal
Pd(II)-catalyzed E/Z isomerization of alkenes is a common process—yet its mechanism remains largely uncharacterized, particularly with non-conjugated alkenes. In this work, the mechanism of Pd(II)-catalyzed E/Z isomerization of unactivated olefins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6226b0f30b5a91131f4a4576ef36137a
https://pubmed.ncbi.nlm.nih.gov/34422450
https://pubmed.ncbi.nlm.nih.gov/34422450
Publikováno v:
ACS Catal
A weakly coordinating monodentate heteroaryl thioether directing group has been developed for use in Pd(II) catalysis to orchestrate key elementary steps in the catalytic cycle that require conformational flexibility in a manner that is difficult to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cbc9ff327cc5edb5fc918438fedcbea
https://doi.org/10.1021/acscatal.9b01471
https://doi.org/10.1021/acscatal.9b01471
Autor:
Jason S. Chen, De-Wei Gao, Omar Apolinar, Mingyu Liu, Peng Liu, Sri Krishna Nimmagadda, Malkanthi K. Karunananda, Keary M. Engle
Publikováno v:
Angewandte Chemie. 131:3963-3967
A palladium(II)-catalyzed enantioselective α-alkylation of azlactones with nonconjugated alkenes is described. The reaction employs a chiral BINOL-derived phosphoric acid as the source of stereoinduction, and a cleavable bidentate directing group ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be8349986ce96b32dc5ffa85f580d12
https://doi.org/10.1002/ange.201814272
https://doi.org/10.1002/ange.201814272
Autor:
Wendy Ann Williams, Ying Zhang, Malkanthi K. Karunananda, Hsien-Cheng Yu, Neal P. Mankad, Kyle J. Clark, Daniel H. Ess
Publikováno v:
ACS Catalysis. 9:2657-2663
The mechanism and heterodinuclear cooperative effects for AgRu-catalyzed alkyne semihydrogenation were analyzed with density-functional theory (DFT) and experiment. This combined effort revealed the following: (1) AgRu-catalyzed diphenylacetylene hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe5237035c3809df085a6a561984176b
https://doi.org/10.1021/acscatal.8b04130
https://doi.org/10.1021/acscatal.8b04130
Autor:
Van T. Tran, Martin D. Eastgate, Steven R. Wisniewski, Keary M. Engle, Roman Kleinmans, Joseph Derosa, Malkanthi K. Karunananda
Publikováno v:
Journal of the American Chemical Society. 140:17878-17883
A nickel-catalyzed conjunctive cross-coupling of simple alkenyl amides with aryl iodides and aryl boronic esters is reported. The reaction is enabled by an electron-deficient olefin (EDO) ligand, dimethyl fumarate, and delivers the desired 1,2-diaryl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4240a31cef800a0c01227e5292ffa4aa
https://doi.org/10.1021/jacs.8b11942
https://doi.org/10.1021/jacs.8b11942
Publikováno v:
Journal of the American Chemical Society. 140:5805-5813
A catalytic method to prepare highly substituted 1,3-dienes from two different alkenes is described using a directed, palladium(II)-mediated C(alkenyl)–H activation strategy. The transformation exhibits broad scope across three synthetically useful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80f33472dff3007703600d214138f4f6
https://doi.org/10.1021/jacs.8b02124
https://doi.org/10.1021/jacs.8b02124
Autor:
Malkanthi K. Karunananda, Keary M. Engle, Mingyu Liu, Yiyang Xiao, Zhen Liu, Jason S. Chen, De-Wei Gao
Publikováno v:
ACS Catalysis. 8:3650-3654
A method to achieve enantioselective 1,4-hydroboration of terminal enynes to access allenyl boronates under CuH catalysis is described. The reaction typically proceeds in a highly stereoselective manner and tolerates an array of synthetically useful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899154724982c17e96736ea4f059f55e
https://doi.org/10.1021/acscatal.8b00626
https://doi.org/10.1021/acscatal.8b00626