Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Malka Popliker"'
Combgap Promotes Ovarian Niche Development and Chromatin Association of EcR-Binding Regions in BR-C.
Autor:
Anna Hitrik, Malka Popliker, Dana Gancz, Zohar Mukamel, Aviezer Lifshitz, Omer Schwartzman, Amos Tanay, Lilach Gilboa
Publikováno v:
PLoS Genetics, Vol 12, Iss 11, p e1006330 (2016)
The development of niches for tissue-specific stem cells is an important aspect of stem cell biology. Determination of niche size and niche numbers during organogenesis involves precise control of gene expression. How this is achieved in the context
Externí odkaz:
https://doaj.org/article/1704b68eeb9c471e9a69b5410afeb016
Autor:
Lilach Gilboa, Amos Tanay, Malka Popliker, Omer Schwartzman, Aviezer Lifshitz, Dana Gancz, Anna Hitrik, Zohar Mukamel
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 12, Iss 11, p e1006330 (2016)
PLoS Genetics, Vol 12, Iss 11, p e1006330 (2016)
The development of niches for tissue-specific stem cells is an important aspect of stem cell biology. Determination of niche size and niche numbers during organogenesis involves precise control of gene expression. How this is achieved in the context
Publikováno v:
Endocrinology. 146:77-84
Previous studies showed that epidermal growth factor (EGF) and TGFα mimic the action of LH on the resumption of oocyte maturation. We tested whether EGF-like agents, such as amphiregulin (AR), epiregulin (ER), and betacellulin (BTC), also mediate th
Publikováno v:
Biology of Reproduction. 71:1807-1812
Meiosis-activating sterol (MAS) was shown to overcome the inhibitory effect of hypoxanthine on spontaneous maturation of mouse oocytes and was suggested to mediate the stimulation of meiosis by gonadotropins. Follicular fluid (FF)-MAS is synthesized
Publikováno v:
Development (Cambridge, England). 141(13)
Tissue homeostasis is maintained by balancing stem cell self-renewal and differentiation. How surrounding cells support this process has not been entirely resolved. Here we show that the chromatin and telomere-binding factor Without children (Woc) is
Publikováno v:
Biology of Reproduction. 64:299-309
In vitro studies on mouse oocytes have shown that two closely related sterols, subsequently named meiosis-activating sterols (MAS), can overcome the inhibitory effect of hypoxanthine on the resumption of meiosis. These sterols are synthesized by cyto
Publikováno v:
Biology of Reproduction. 47:245-253
Proteinases and their inhibitors control follicular connective tissue remodeling associated with follicular rupture. We exammed the regulation and cellular localization of plasminogen activator inhibitor type-i (PAl-i) and tissue inhibitor of metallo
Publikováno v:
Molecular reproduction and development. 75(10)
Gonadotropic stimulation of meiotic resumption in mice is dependent upon mitogen-activated protein kinase (MAPK) activation in the somatic compartment of the follicle. By contrast, spontaneous resumption of meiosis is independent of MAPK activation.
Publikováno v:
Molecular and cellular endocrinology. 282(1-2)
Cultures of mural granulosa cells (mGCs) and cumulus oocyte complexes (COCs) were employed to investigate various aspects of follicle cell function and response to gonadotropins. Yet, such studies do not reveal the intricate cell-to-cell interactions
Publikováno v:
Endocrinology. 148(9)
Steroids mediate the gonadotropic stimulus of oocyte maturation in fish and amphibians. Such a role of steroids in mammals has not been confirmed until recently. A series of studies presented data suggesting that steroids might be involved in meiosis