Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Malka Kitayner"'
Autor:
Zippora Shakked, Remo Rohs, Malka Kitayner, Dov Rabinovich, Barry Honig, Haim Rozenberg, Oded Suad
Publikováno v:
Nature Structural & Molecular Biology. 17:423-429
p53 binds as a tetramer to DNA targets consisting of two decameric half-sites separated by a variable spacer. Here we present high-resolution crystal structures of complexes between p53 core-domain tetramers and DNA targets consisting of contiguous h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84792dac89fbaaf7da4d5cd4cddefd98
https://doi.org/10.1038/nsmb.1800
https://doi.org/10.1038/nsmb.1800
Autor:
Zippora Shakked, Malka Kitayner, Naama Kessler, Haim Rozenberg, Lihi Shaulov, Tali E. Haran, Dov Rabinovich
Publikováno v:
Molecular Cell. 22:741-753
The tumor-suppressor protein p53 is among the most effective of the cell's natural defenses against cancer. In response to cellular stress, p53 binds as a tetramer to diverse DNA targets containing two decameric half-sites, thereby activating the exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83087db2d13909a1ec3359c363daa464
https://doi.org/10.1016/j.molcel.2006.05.015
https://doi.org/10.1016/j.molcel.2006.05.015
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 61:236-246
Runt-domain (RD) proteins are transcription factors that play fundamental roles in various developmental pathways. They bind specifically to DNA sequences of the general form PyGPyGGTPy (Py = pyrimidine), through which they regulate transcription of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3faef8b68037cb963ecf607749d214a0
https://doi.org/10.1107/s0907444904032378
https://doi.org/10.1107/s0907444904032378
Autor:
Pratik Vyas, Itai Beno, Donald M. Crothers, Malka Kitayner, Naama Kessler, Zippora Shakked, Tali E. Haran, Zhiqun Xi
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 33:16-17
The tumor suppressor protein p53 binds sequence-specifically to defined DNA targets in the genome. The consensus DNA response element (RE) consists of two decameric half-sites (HS) with the general...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58358fea2216ee39e2c5c07ef8e0f867
https://doi.org/10.1080/07391102.2015.1032569
https://doi.org/10.1080/07391102.2015.1032569