Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Malka Kitayner"'
Autor:
Zippora Shakked, Remo Rohs, Malka Kitayner, Dov Rabinovich, Barry Honig, Haim Rozenberg, Oded Suad
Publikováno v:
Nature Structural & Molecular Biology. 17:423-429
p53 binds as a tetramer to DNA targets consisting of two decameric half-sites separated by a variable spacer. Here we present high-resolution crystal structures of complexes between p53 core-domain tetramers and DNA targets consisting of contiguous h
Autor:
Zippora Shakked, Malka Kitayner, Naama Kessler, Haim Rozenberg, Lihi Shaulov, Tali E. Haran, Dov Rabinovich
Publikováno v:
Molecular Cell. 22:741-753
The tumor-suppressor protein p53 is among the most effective of the cell's natural defenses against cancer. In response to cellular stress, p53 binds as a tetramer to diverse DNA targets containing two decameric half-sites, thereby activating the exp
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 61:236-246
Runt-domain (RD) proteins are transcription factors that play fundamental roles in various developmental pathways. They bind specifically to DNA sequences of the general form PyGPyGGTPy (Py = pyrimidine), through which they regulate transcription of
Autor:
Pratik Vyas, Itai Beno, Donald M. Crothers, Malka Kitayner, Naama Kessler, Zippora Shakked, Tali E. Haran, Zhiqun Xi
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 33:16-17
The tumor suppressor protein p53 binds sequence-specifically to defined DNA targets in the genome. The consensus DNA response element (RE) consists of two decameric half-sites (HS) with the general...
Autor:
Tan, Qihua1 (AUTHOR), Møller, Anaïs Marie Julie2,3 (AUTHOR), Qiu, Chuan4 (AUTHOR), Madsen, Jonna Skov5,6 (AUTHOR), Shen, Hui4 (AUTHOR), Bechmann, Troels7,8 (AUTHOR), Delaisse, Jean-Marie2,9 (AUTHOR), Kristensen, Bjarne Winther9,10 (AUTHOR), Deng, Hong-Wen4 (AUTHOR), Karasik, David11 (AUTHOR), Søe, Kent2,9,12 (AUTHOR) kent.soee@rsyd.dk
Publikováno v:
Clinical Epigenetics. 3/13/2023, Vol. 15 Issue 1, p1-14. 14p.
Autor:
Vyas, Pratik, Beno, Itai, Zhiqun Xi, Stein, Yan, Golovenko, Dmitrij, Kessler, Naama, Rotter, Varda, Shakked, Zippora, Haran, Tali E.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/3/2017, Vol. 114 Issue 40, p10624-10629, 6p
Publikováno v:
Nucleic Acids Research; Dec2005, Vol. 33 Issue 22, p7048-7057, 10p
Autor:
Krishnarao Appasani
Cryo-electron microscopy, in combination with tomography, has emerged as a new technology for visualizing molecular structures at a resolution beyond even 1 Å. Using this technology has revealed the native molecular details of viruses, membranes, en