Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Malka Cohen"'
Autor:
Malka Cohen-Armon
Publikováno v:
Biology and Life Sciences Forum, Vol 21, Iss 1, p 14 (2023)
The modified phenanthridine PJ34 blocks the post-translational modifications of specific proteins highly expressed in human malignant cells. This exclusively arrests mitosis in human malignant cells by inserting flaws in their mitotic spindle structu
Externí odkaz:
https://doaj.org/article/d4765785b6f84fddaa5f86005f57fcc3
Autor:
Malka Cohen-Armon
Publikováno v:
Cells, Vol 11, Iss 9, p 1576 (2022)
This overview presents recent evidence for a long-lasting PARP1 activation by a variety of signal transduction mechanisms, mediating signal-induced gene expression and chromatin remodeling. This mode of PARP1 activation has been reported in a variety
Externí odkaz:
https://doaj.org/article/51220701b3a945b08597d53598167037
Autor:
Shirah Malka, Cohen
Publikováno v:
一神教世界 = The world of monotheistic religions. 13:1-17
20世紀初頭の日本人小説家谷崎潤一郎やユダヤ人小説家のダヴィッド・フォーゲルのようなモダニストの作家達は、モダニティーが彼らをその伝統から切り離した世界に立ち向かわなけ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::1685e18676f7f9031b114b7c22daecaa
http://id.nii.ac.jp/1707/00028949/
http://id.nii.ac.jp/1707/00028949/
Autor:
Malka Cohen-Armon
Publikováno v:
International Journal of Molecular Sciences. 24:7538
Unexpectedly, the affinity of the seven-transmembrane muscarinic acetylcholine receptors for their agonists is modulated by membrane depolarization. Recent reports attribute this characteristic to an embedded charge movement in the muscarinic recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b757c9d67f091793a792ee4c302d4f26
https://doi.org/10.3390/ijms24087538
https://doi.org/10.3390/ijms24087538
Autor:
Malka Cohen-Armon
Publikováno v:
Drug discovery today. 27(5)
NuMA (nuclear mitotic apparatus) protein is indispensable in the mitosis of human proliferating cells, both malignant and benign. The progression of mitosis requires stable spindles, which depend on the bipolar clustering of NuMA within the spindles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbdc2168f16f780d34dcf7b99f850f8
https://pubmed.ncbi.nlm.nih.gov/35143964
https://pubmed.ncbi.nlm.nih.gov/35143964
Publikováno v:
Oncotarget
Recent reports demonstrate an exclusive eradication of a variety of human cancer cells by the modified phenanthridine PJ34. Their eradication during mitosis is attributed to PJ34 preventing NuMA clustering in the mitotic spindle poles of human malign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835fe208e3769aef0bf37448a805f575
http://europepmc.org/articles/PMC6817443
http://europepmc.org/articles/PMC6817443
Autor:
Shirah Malka, Cohen
Publikováno v:
一神教世界 = The world of monotheistic religions. 10:41-57
The emergence of nationalism in the late 18th century greatly impacted human society and culture, making it impossible to think outside its framework. This impact also resulted in the emergence of the concept of "National Literature". To better under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::6ea0f6c3848b4e49c4756f9e9e7413f5
http://id.nii.ac.jp/1707/00026666/
http://id.nii.ac.jp/1707/00026666/
Autor:
Malka Cohen-Armon
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1628, p 1628 (2020)
Cancers, Vol 12, Iss 1628, p 1628 (2020)
This overview summarizes recent data disclosing the efficacy of the PARP inhibitor PJ34 in exclusive eradication of a variety of human cancer cells without impairing healthy proliferating cells. Its cytotoxic activity in cancer cells is attributed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d0539a3a186e977ec0f9c4eb64da3b
http://europepmc.org/articles/PMC7352794
http://europepmc.org/articles/PMC7352794
Autor:
Leonid Visochek, Malka Cohen-Armon
Publikováno v:
Oncotarget
A synergism between PARP1 and phosphorylated Erk mediating IEG (immediate early gene) expression has been recently reported in cerebral neurons and cardiomyocytes. Stimulation induced PARP-Erk synergism was required for IEG expression underlying syna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b741fd77444998b545064dedb536cee
https://doi.org/10.18632/oncotarget.25633
https://doi.org/10.18632/oncotarget.25633
Autor:
Shai Izraeli, Leonid Mittelman, Malka Cohen-Armon, Leonid Visochek, Talia Golan, Dikla Atias, Asher Castiel, Michael Elkin, Tamar Peretz
Publikováno v:
Oncotarget
// Leonid Visochek 1 , Asher Castiel 2 , Leonid Mittelman 3 , Michael Elkin 4 , Dikla Atias 2 , Talia Golan 2 , Shai Izraeli 2, 5 , Tamar Peretz 4 , Malka Cohen-Armon 1, 6 1 The Neufeld Cardiac Research Institute, Department of Physiology and Pharmac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e19fc0aedc50027c69ed431116e1ffc
http://europepmc.org/articles/PMC5400547
http://europepmc.org/articles/PMC5400547