Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Malka Attar-Namdar"'
Autor:
Bitya Raphael-Mizrahi, Malka Attar-Namdar, Mukesh Chourasia, Maria G Cascio, Avital Shurki, Joseph Tam, Moshe Neuman, Neta Rimmerman, Zvi Vogel, Arie Shteyer, Roger G Pertwee, Andreas Zimmer, Natalya M Kogan, Itai Bab, Yankel Gabet
Publikováno v:
eLife, Vol 11 (2022)
The endocannabinoid system consists mainly of 2-arachidonoylglycerol and anandamide, as well as cannabinoid receptor type 1 and type 2 (CB2). Based on previous studies, we hypothesized that a circulating peptide previously identified as osteogenic gr
Externí odkaz:
https://doaj.org/article/b1b065666f49413c8b2026a4bcaff88e
Publikováno v:
Molecules, Vol 24, Iss 20, p 3719 (2019)
Oleoyl serine (OS), an endogenous fatty acyl amide (FAA) found in bone, has been shown to have an anti-osteoporotic effect. OS, being an amide, can be hydrolyzed in the body by amidases. Hindering its amide bond by introducing adjacent substituents h
Externí odkaz:
https://doaj.org/article/ea8fc8bd9ea64b9d92a31e2109679e17
Autor:
Bitya Raphael-Mizrahi, Malka Attar-Namdar, Mukesh Chourasia, Maria G Cascio, Avital Shurki, Joseph Tam, Moshe Neuman, Neta Rimmerman, Zvi Vogel, Arie Shteyer, Roger G Pertwee, Andreas Zimmer, Natalya M Kogan, Itai Bab, Yankel Gabet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24c5ecc3b06693d8e61eee26c040b598
https://doi.org/10.7554/elife.65834.sa2
https://doi.org/10.7554/elife.65834.sa2
Autor:
Bitya Raphael-Mizrahi, Malka Attar-Namdar, Mukesh Chourasia, Maria G Cascio, Avital Shurki, Joseph Tam, Moshe Neuman, Neta Rimmerman, Zvi Vogel, Arie Shteyer, Roger G Pertwee, Andreas Zimmer, Natalya M Kogan, Itai Bab, Yankel Gabet
Publikováno v:
eLife. 11
The endocannabinoid system consists mainly of 2-arachidonoylglycerol and anandamide, as well as cannabinoid receptor type 1 and type 2 (CB2). Based on previous studies, we hypothesized that a circulating peptide previously identified as osteogenic gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b054b47f93988f40244d8bc6d209c340
https://pubmed.ncbi.nlm.nih.gov/35604006
https://pubmed.ncbi.nlm.nih.gov/35604006
Publikováno v:
Molecules
Molecules, Vol 24, Iss 20, p 3719 (2019)
Volume 24
Issue 20
Molecules, Vol 24, Iss 20, p 3719 (2019)
Volume 24
Issue 20
Oleoyl serine (OS), an endogenous fatty acyl amide (FAA) found in bone, has been shown to have an anti-osteoporotic effect. OS, being an amide, can be hydrolyzed in the body by amidases. Hindering its amide bond by introducing adjacent substituents h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ee9f018c3c877b736d06762b1de322
http://europepmc.org/articles/PMC6832161
http://europepmc.org/articles/PMC6832161
Autor:
Alina Nemirovski, Malka Attar-Namdar, Yshaia Langer, Yankel Gabet, Joseph Tam, Raphael Mechoulam, Shira Hirsch, Reem Smoum, Asaad Gammal, Rivka Hadar, Yehuda Pollak, Saja Baraghithy, Megan E. Rech, Itai Bab, Adi Drori, Christian P. Schaaf, Varda Gross-Tsur
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 34(1)
Among a multitude of hormonal and metabolic complications, individuals with Prader-Willi syndrome (PWS) exhibit significant bone abnormalities, including decreased BMD, osteoporosis, and subsequent increased fracture risk. Here we show in mice that l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2f11f3823266fb863458a871e4806d
https://pubmed.ncbi.nlm.nih.gov/30347474
https://pubmed.ncbi.nlm.nih.gov/30347474
Autor:
Ana V. Villarreal Escudero, Raphael Mechoulam, Malka Attar-Namdar, Natalya M. Kogan, Silvina Friedlander-Barenboim, Yankel Gabet, Eitan Melamed, Neashan Mathavan, Itai Bab, Bitya Raphael, Saja Baraghithy, Aviva Breuer, Kathryn S. Stok, Alon Bajayo, Elad Wasserman, Ralph Müller, Hanna Isaksson, Rachel E. Sondergaard
Publikováno v:
Journal of Bone and Mineral Research. 30:1905-1913
Cannabinoid ligands regulate bone mass, but skeletal effects of cannabis (marijuana and hashish) have not been reported. Bone fractures are highly prevalent, involving prolonged immobilization and discomfort. Here we report that the major non-psychoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1975d78419884855e59fe9431b872773
https://doi.org/10.1002/jbmr.2513
https://doi.org/10.1002/jbmr.2513
Autor:
Baruch Frenkel, Itai Bab, Mona Dvir-Ginzberg, Esther Shohami, Andreas Zimmer, Vardit Kram, Malka Attar-Namdar, Raphael Mechoulam, Orr Ofek
Publikováno v:
Journal of Bone and Mineral Research
CB2 is a Gi protein–coupled receptor activated by endo- and phytocannabinoids, thus inhibiting stimulated adenylyl cyclase activity. CB2 is expressed in bone cells and Cb2 null mice show a marked age-related bone loss. CB2-specific agonists both at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67baf83889347c86aa34649d9f147be4
https://doi.org/10.1002/jbmr.228
https://doi.org/10.1002/jbmr.228
Autor:
Pietro Marini, Raphael Mechoulam, Reem Smoum, Aviva Breuer, Naama Mussai, Mukesh Chourasia, Malka Attar-Namdar, Saja Baraghithy, Natalya M. Kogan, Bitya Raphael, Roger G. Pertwee, Daniele Bolognini, Maria Grazia Cascio, Avital Shurki, Itai Bab
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(28)
Activation of the CB2 receptor is apparently an endogenous protective mechanism. Thus, it restrains inflammation and protects the skeleton against age-related bone loss. However, the endogenous cannabinoids, as well as Δ(9)-tetrahydrocannabinol, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027b09517f67d4a4566c37d587c33e38
https://pubmed.ncbi.nlm.nih.gov/26124120
https://pubmed.ncbi.nlm.nih.gov/26124120
Autor:
Natalya M, Kogan, Eitan, Melamed, Elad, Wasserman, Bitya, Raphael, Aviva, Breuer, Kathryn S, Stok, Rachel, Sondergaard, Ana V Villarreal, Escudero, Saja, Baraghithy, Malka, Attar-Namdar, Silvina, Friedlander-Barenboim, Neashan, Mathavan, Hanna, Isaksson, Raphael, Mechoulam, Ralph, Müller, Alon, Bajayo, Yankel, Gabet, Itai, Bab
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30(10)
Cannabinoid ligands regulate bone mass, but skeletal effects of cannabis (marijuana and hashish) have not been reported. Bone fractures are highly prevalent, involving prolonged immobilization and discomfort. Here we report that the major non-psychoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::223ff4636dc477db85fb6650effa3e1f
https://pubmed.ncbi.nlm.nih.gov/25801536
https://pubmed.ncbi.nlm.nih.gov/25801536