Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First In Vivo Experiments

Autor: Frei, Angelo, Elliott, Alysha G, Kan, Alex, Dinh, Hue, Bräse, Stefan, Bruce, Alice E, Bruce, Mitchell R, Chen, Feng, Humaidy, Dhirgam, Jung, Nicole, King, A Paden, Lye, Peter G, Maliszewska, Hanna K, Mansour, Ahmed M, Matiadis, Dimitris, Muñoz, María Paz, Pai, Tsung-Yu, Pokhrel, Shyam, Sadler, Peter J, Sagnou, Marina, Taylor, Michelle, Wilson, Justin J, Woods, Dean, Zuegg, Johannes, Meyer, Wieland, Cain, Amy K, Cooper, Matthew A, Blaskovich, Mark A T

Publikováno v: Frei, Angelo; Elliott, Alysha G; Kan, Alex; Dinh, Hue; Bräse, Stefan; Bruce, Alice E; Bruce, Mitchell R; Chen, Feng; Humaidy, Dhirgam; Jung, Nicole; King, A Paden; Lye, Peter G; Maliszewska, Hanna K; Mansour, Ahmed M; Matiadis, Dimitris; Muñoz, María Paz; Pai, Tsung-Yu; Pokhrel, Shyam; Sadler, Peter J; Sagnou, Marina; ... (2022). Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First In Vivo Experiments. JACS Au, 2(10), pp. 2277-2294. ACS Publications 10.1021/jacsau.2c00308
Journal of the American Chemical Society, 2 (10), 2277–2294

There are currently fewer than 10 antifungal drugs in clinical development, but new fungal strains that are resistant to most current antifungals are spreading rapidly across the world. To prevent a second resistance crisis, new classes of antifungal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0285c29d197416c68cc534a09bbe0f6a
https://boris.unibe.ch/174374/1/jacsau.2c00308.pdf

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