Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Malini Rethnam"'
Autor:
Takayoshi Matsumura, Haruhito Totani, Yoshitaka Gunji, Masahiro Fukuda, Rui Yokomori, Jianwen Deng, Malini Rethnam, Chong Yang, Tze King Tan, Tadayoshi Karasawa, Kazuomi Kario, Masafumi Takahashi, Motomi Osato, Takaomi Sanda, Toshio Suda
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The transcription factor MYB has been shown to regulate haematopoietic stem cells but there could be lineage specific enhancers. Here, using lineage tracing and single cell sequencing the authors characterise a Myb −68 enhancer that regulates the d
Externí odkaz:
https://doaj.org/article/f7b34ab06eff47b1947cf8949cde1d29
Publikováno v:
Biochemical and Biophysical Research Communications. 534:843-848
Multiple myeloma (MM) is an intractable hematological malignancy characterized by abnormal plasma cells in the bone marrow (BM) and increased osteolytic lesions. Within the BM niche, mesenchymal stem cells (MSCs) have been proposed to contribute to f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc854ca1b83c785ce07ba12ad36fd71d
https://doi.org/10.1016/j.bbrc.2020.10.093
https://doi.org/10.1016/j.bbrc.2020.10.093
Autor:
Malini Rethnam, Darren Qiancheng Tan, Shi Hao Tan, Jia Li, Rui Yokomori, Ying Li, Henry Yang, Takaomi Sanda, Toshio Suda
Publikováno v:
Blood advances. 6(18)
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy with poor clinical outcomes. Dysregulated MYC expression, which is associated with protein arginine methyltransferase 5 (PRMT5) dependency, is a recu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71b170a55bb34e3b586404582af3dcd
https://pubmed.ncbi.nlm.nih.gov/35482445
https://pubmed.ncbi.nlm.nih.gov/35482445
Publikováno v:
Biochemical and Biophysical Research Communications. 508:1175-1181
Multiple myeloma (MM) is a hematological malignancy characterized by clonal proliferation of abnormal plasma cells. MM dysregulates the homeostasis of the bone niche cells like osteoclasts and osteoblasts, responsible for the bone maintenance leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32930cbe61aa1ba46c0f05d4d9d77c4
https://doi.org/10.1016/j.bbrc.2018.11.178
https://doi.org/10.1016/j.bbrc.2018.11.178
Publikováno v:
Blood. 138:1132-1132
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is an aggressive hematologic cancer that stems from plasmacytoid dendritic cells (pDCs) and predisposes to leukemic transformation. Other than Tagraxofusp-erzs, a recently approved targeted therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c26be04dfac31130716a3328a41cde30
https://doi.org/10.1182/blood-2021-146108
https://doi.org/10.1182/blood-2021-146108
Publikováno v:
Blood. 136:13-13
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and clinically aggressive hematologic cancer that arises from malignant transformation of plasmacytoid dendritic cells (pDCs) and is predisposed to leukemic transformation. Apart from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5c2661a5c6ba722427ba1f789eec7af
https://doi.org/10.1182/blood-2020-133352
https://doi.org/10.1182/blood-2020-133352