Zobrazeno 1 - 10
of 14 485
pro vyhledávání: '"Malina A"'
Autor:
Huan Zhang, Yongqiang He, Yuqing Zhao, Malina Axinbai, Yuwei Hu, Shilei Liu, Jingmin Kong, Jinhui Sun, Liping Zhang
Publikováno v:
Hereditas, Vol 161, Iss 1, Pp 1-14 (2024)
Abstract Background The most common progressive form of non-alcoholic fatty liver disease (NAFLD) is non-alcoholic steatohepatitis (NASH), which is characterized by the development of cirrhosis, and requires liver transplantation. We screened for the
Externí odkaz:
https://doaj.org/article/8effe56cc7ed4c52ba08d6782c5a87e5
Autor:
Nian E. Zhou, Su Tang, Xuelin Bian, Maloy K. Parai, Inna V. Krieger, Armando Flores, Pradeep K. Jaiswal, Radha Bam, Jeremy L. Wood, Zhe Shi, Laura J. Stevens, Trevor Scobey, Meghan V. Diefenbacher, Fernando R. Moreira, Thomas J. Baric, Arjun Acharya, Joonyoung Shin, Manish M. Rathi, Karen C. Wolff, Laura Riva, Malina A. Bakowski, Case W. McNamara, Nicholas J. Catanzaro, Rachel L. Graham, David C. Schultz, Sara Cherry, Yoshihiro Kawaoka, Peter J. Halfmann, Ralph S. Baric, Mark R. Denison, Timothy P. Sheahan, James C. Sacchettini
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114929- (2024)
Summary: Safe, effective, and low-cost oral antiviral therapies are needed to treat those at high risk for developing severe COVID-19. To that end, we performed a high-throughput screen to identify non-peptidic, non-covalent inhibitors of the SARS-Co
Externí odkaz:
https://doaj.org/article/fee5e4e3bedd475abadbb75db127898b
Autor:
Huan Zhang, Malina Axinbai, Yuqing Zhao, Jiaoyang Wei, Tongshuo Qu, Jingmin Kong, Yongqiang He, Liping Zhang
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-14 (2023)
Abstract Background The morbidity and mortality rates of patients with non-alcoholic fatty liver disease (NAFLD) have been steadily increasing in recent years. Previous studies have confirmed the important role of ferroptosis in NAFLD development; ho
Externí odkaz:
https://doaj.org/article/fe06e9228ea143cebf6b928910ac187f
Autor:
Leonie Grosse, Malina A. Späh, Corinna Börner, Julian F. Schnabel, Anne C. Meuche, Barbara Parzefall, Ute Breuer, Birgit Warken, Alexandra Sitzberger, Matthias Hösl, Florian Heinen, Steffen Berweck, Sebastian A. Schröder, Michaela V. Bonfert
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundImpaired selective motor control, weakness and spasticity represent the key characteristics of motor disability in the context of bilateral spastic cerebral palsy. Independent walking ability is an important goal and training of the gluteal
Externí odkaz:
https://doaj.org/article/f75d982fdfcc436da0949b957884397b
Publikováno v:
Microorganisms, Vol 11, Iss 12, p 2845 (2023)
Leishmaniasis is a group of vector-borne, parasitic diseases caused by over 20 species of the protozoan Leishmania spp. The three major disease classifications, cutaneous, visceral, and mucocutaneous, have a range of clinical manifestations from self
Externí odkaz:
https://doaj.org/article/de5072f6830642a2935a0e06b858bbf0
Autor:
Leonie Grosse, Julian F. Schnabel, Corinna Börner-Schröder, Malina A. Späh, Anne C. Meuche, Nico Sollmann, Ute Breuer, Birgit Warken, Matthias Hösl, Florian Heinen, Steffen Berweck, Sebastian A. Schröder, Michaela V. Bonfert
Publikováno v:
Children, Vol 10, Iss 11, p 1768 (2023)
Background: For children and adolescents affected by bilateral spastic cerebral palsy (BSCP), non-invasive neurostimulation with repetitive neuromuscular magnetic stimulation (rNMS) combined with physical exercises, conceptualized as functional rNMS
Externí odkaz:
https://doaj.org/article/d5c8e70fa78640f29dbd7edcdaf795c7
Autor:
Yuqing Zhao, Yingying Song, Huan Zhang, Tongshuo Qu, Malina Axinbai, Yidian Yang, Liping Zhang
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
ObjectiveIn this study, we aimed to perform a network meta-analysis to compare the effectiveness of NAs in decreasing the reactivation of HBV, reducing chemotherapy disruption, and improving survival in oncology patients.MethodsRelevant randomized co
Externí odkaz:
https://doaj.org/article/357b05c6ffb14add8e68b054bbc5b681
Autor:
Britton Boras, Rhys M. Jones, Brandon J. Anson, Dan Arenson, Lisa Aschenbrenner, Malina A. Bakowski, Nathan Beutler, Joseph Binder, Emily Chen, Heather Eng, Holly Hammond, Jennifer Hammond, Robert E. Haupt, Robert Hoffman, Eugene P. Kadar, Rob Kania, Emi Kimoto, Melanie G. Kirkpatrick, Lorraine Lanyon, Emma K. Lendy, Jonathan R. Lillis, James Logue, Suman A. Luthra, Chunlong Ma, Stephen W. Mason, Marisa E. McGrath, Stephen Noell, R. Scott Obach, Matthew N. O’ Brien, Rebecca O’Connor, Kevin Ogilvie, Dafydd Owen, Martin Pettersson, Matthew R. Reese, Thomas F. Rogers, Romel Rosales, Michelle I. Rossulek, Jean G. Sathish, Norimitsu Shirai, Claire Steppan, Martyn Ticehurst, Lawrence W. Updyke, Stuart Weston, Yuao Zhu, Kris M. White, Adolfo García-Sastre, Jun Wang, Arnab K. Chatterjee, Andrew D. Mesecar, Matthew B. Frieman, Annaliesa S. Anderson, Charlotte Allerton
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The 3CL protease of SARS-CoV-2 is inhibited by PF-00835231 in vitro. Here, the authors show that the prodrug PF-07304814 has broad spectrum activity, inhibiting SARS-CoV and SARS-CoV-2 in mice and its ADME and safety profile support clinical developm
Externí odkaz:
https://doaj.org/article/7c0ac56767d64fb5af7714d7f3a62322
Autor:
John, Peter St., Lin, Dejun, Binder, Polina, Greaves, Malcolm, Shah, Vega, John, John St., Lange, Adrian, Hsu, Patrick, Illango, Rajesh, Ramanathan, Arvind, Anandkumar, Anima, Brookes, David H, Busia, Akosua, Mahajan, Abhishaike, Malina, Stephen, Prasad, Neha, Sinai, Sam, Edwards, Lindsay, Gaudelet, Thomas, Regep, Cristian, Steinegger, Martin, Rost, Burkhard, Brace, Alexander, Hippe, Kyle, Naef, Luca, Kamata, Keisuke, Armstrong, George, Boyd, Kevin, Cao, Zhonglin, Chou, Han-Yi, Chu, Simon, Costa, Allan dos Santos, Darabi, Sajad, Dawson, Eric, Didi, Kieran, Fu, Cong, Geiger, Mario, Gill, Michelle, Hsu, Darren, Kaushik, Gagan, Korshunova, Maria, Kothen-Hill, Steven, Lee, Youhan, Liu, Meng, Livne, Micha, McClure, Zachary, Mitchell, Jonathan, Moradzadeh, Alireza, Mosafi, Ohad, Nashed, Youssef, Paliwal, Saee, Peng, Yuxing, Rabhi, Sara, Ramezanghorbani, Farhad, Reidenbach, Danny, Ricketts, Camir, Roland, Brian, Shah, Kushal, Shimko, Tyler, Sirelkhatim, Hassan, Srinivasan, Savitha, Stern, Abraham C, Toczydlowska, Dorota, Veccham, Srimukh Prasad, Venanzi, Niccolò Alberto Elia, Vorontsov, Anton, Wilber, Jared, Wilkinson, Isabel, Wong, Wei Jing, Xue, Eva, Ye, Cory, Yu, Xin, Zhang, Yang, Zhou, Guoqing, Zandstein, Becca, Dallago, Christian, Trentini, Bruno, Kucukbenli, Emine, Rvachov, Timur, Calleja, Eddie, Israeli, Johnny, Clifford, Harry, Haukioja, Risto, Haemel, Nicholas, Tretina, Kyle, Tadimeti, Neha, Costa, Anthony B
Artificial Intelligence models encoding biology and chemistry are opening new routes to high-throughput and high-quality in-silico drug development. However, their training increasingly relies on computational scale, with recent protein language mode
Externí odkaz:
http://arxiv.org/abs/2411.10548
Autor:
Leonie Grosse, Anne C. Meuche, Barbara Parzefall, Corinna Börner, Julian F. Schnabel, Malina A. Späh, Pia Klug, Nico Sollmann, Luisa Klich, Matthias Hösl, Florian Heinen, Steffen Berweck, Sebastian A. Schröder, Michaela V. Bonfert
Publikováno v:
Children, Vol 10, Iss 10, p 1584 (2023)
Non-invasive neurostimulation as an adjunctive intervention to task-specific motor training is an approach to foster motor performance in patients affected by upper motor neuron syndrome (UMNS). Here, we present first-line data of repetitive neuromus
Externí odkaz:
https://doaj.org/article/9ab04ec36a4041feabd82266df28816e