Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Malin Kele"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Preclinical transplantations using human neuroepithelial stem (NES) cells in spinal cord injury models have exhibited promising results and demonstrated cell integration and functional improvement in transplanted animals. Previous studies have relied
Externí odkaz:
https://doaj.org/article/6a8c2c6b71124226b29cc497e6a8d59f
Autor:
Javier Calvo-Garrido, Camilla Maffezzini, Florian A. Schober, Paula Clemente, Elias Uhlin, Malin Kele, Henrik Stranneheim, Nicole Lesko, Helene Bruhn, Per Svenningsson, Anna Falk, Anna Wedell, Christoph Freyer, Anna Wredenberg
Publikováno v:
Stem Cell Reports, Vol 12, Iss 4, Pp 696-711 (2019)
Summary: Neurodegenerative disorders are an increasingly common and irreversible burden on society, often affecting the aging population, but their etiology and disease mechanisms are poorly understood. Studying monogenic neurodegenerative diseases w
Externí odkaz:
https://doaj.org/article/325a48b5ac9c47b4bce704a2ebf2353e
Autor:
Anna Wredenberg, Paula Clemente, Christoph Freyer, Anna Wedell, Elias Uhlin, Camilla Maffezzini, Henrik Stranneheim, Nicole Lesko, Florian A. Schober, Malin Kele, Per Svenningsson, Javier Calvo-Garrido, Anna Falk, Helene Bruhn
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 12, Iss 4, Pp 696-711 (2019)
Stem Cell Reports, Vol 12, Iss 4, Pp 696-711 (2019)
Summary Neurodegenerative disorders are an increasingly common and irreversible burden on society, often affecting the aging population, but their etiology and disease mechanisms are poorly understood. Studying monogenic neurodegenerative diseases wi
Autor:
Malin Kele, Muhammad Zakaria, Göran Annerén, Mansoureh Shahsavani, Anna Falk, Jan Hoeber, Maria Sobol, Niklas Dahl, Joakim Klar, Jens Schuster, Ambrin Fatima, Loora Laan
Publikováno v:
Clinical Epigenetics
Background Down syndrome (DS) is characterized by neurodevelopmental abnormalities caused by partial or complete trisomy of human chromosome 21 (T21). Analysis of Down syndrome brain specimens has shown global epigenetic and transcriptional changes b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fef917a3c433ae0df893b1a8b53b5a4
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-398619
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-398619
Autor:
Jakub Piotr Fichna, Anna Falk, Malin Kele, Joanna Wojsiat, Jan Ilkowski, Krzysztof Bojakowski, Anna Filipek-Gliszczynska, Maria Barcikowska-Kotowicz, Marcelina Szczerba, Izabela Makalowska, Beata Pepłońska, Magdalena Skrzypczak, Aleksandra Szybinska, Harriet Ronnholm, Cezary Zekanowski, Michal Kabza, Anna Barczak, Maria Styczyńska, Michalina Wezyk, Kelly Day, Mariusz Berdynski, Urszula Wojda, Marzena Zboch, Krzysztof Ginalski
Publikováno v:
Journal of Alzheimer's Disease. 62:175-202
The BRCA1 protein, one of the major players responsible for DNA damage response has recently been linked to Alzheimer's disease (AD). Using primary fibroblasts and neurons reprogrammed from induced pluripotent stem cells (iPSC) derived from familial
Autor:
Matti Lam, Damla Etal, Fredrik Karlsson, Kent Imaizumi, Hideyuki Okano, Ryan Hicks, Malin Kele, Anders Lundin, Anna Falk, Jonathan Cairns, Maryam Clausen, Jun Kohyama, Tsukasa Sanosaka
Publikováno v:
Genes to Cells
We used single‐cell RNA sequencing (seq) on several human induced pluripotent stem (iPS) cell‐derived neural stem cell (NSC) lines and one fetal brain‐derived NSC line to study inherent cell type heterogeneity at proliferating neural stem cell
Autor:
Mohsen Moslem, Loora Laan, Sergiy V. Korol, Anna Falk, Britt-Marie Anderlid, Rebecca Morse, Matti Lam, Niklas Dahl, Robin Pronk, Per Uhlén, Patrick F. Sullivan, Elias Uhlin, Harriet Ronnholm, Julien Bryois, Ivar Dehnisch Ellström, Malin Kele, Jessica Olive, Lauri Louhivuori
Publikováno v:
Experimental Cell Research. 383:111469
We generated human iPS derived neural stem cells and differentiated cells from healthy control individuals and an individual with autism spectrum disorder carrying bi-allelic NRXN1-alpha deletion. We investigated the expression of NRXN1-alpha during
Publikováno v:
Journal of Visualized Experiments.
Xeno-free and fully defined conditions are key parameters for robust and reproducible generation of homogenous human induced pluripotent stem (hiPS) cells. Maintenance of hiPS cells on feeder cells or undefined matrices are susceptible to batch varia
Autor:
Anna Falk, Malin Kele
Publikováno v:
International Journal of Stem cell Research & Therapy. 3
Autor:
Elias, Uhlin, Harriet, Rönnholm, Kelly, Day, Malin, Kele, Kristiina, Tammimies, Sven, Bölte, Anna, Falk
Publikováno v:
Stem cell research. 18
Human induced pluripotent stem (hiPS) cell lines CTRL-9-II and CTRL-10-I were derived from healthy monozygotic twin donors using non-integrating RNA based Sendai virus reprogramming and cultured in a xeno-free chemically defined condition. The establ