Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Malin Hernebring"'
Publikováno v:
Frontiers in Aging, Vol 2 (2021)
Lifespan analyses are important for advancing our understanding of the aging process. There are two major issues in performing lifespan studies: 1) late-stage animal lifespan analysis may include animals with non-terminal, yet advanced illnesses, whi
Externí odkaz:
https://doaj.org/article/2b07586694f04857ab1f222c110a7d30
Autor:
Julia Adelöf, My Andersson, Michelle Porritt, Anne Petersen, Madeleine Zetterberg, John Wiseman, Malin Hernebring
Publikováno v:
BMC Neuroscience, Vol 19, Iss 1, Pp 1-15 (2018)
Abstract Background The proteasome system plays an important role in synaptic plasticity. Induction and maintenance of long term potentiation is directly dependent on selective targeting of proteins for proteasomal degradation. The 20S proteasome act
Externí odkaz:
https://doaj.org/article/4f116fb9727a4fcea7087870547ae017
Publikováno v:
Aging Cell
With age, protein damage accumulates and increases the risk of age‐related diseases. The proteasome activator PA28αβ is involved in protein damage clearance during early embryogenesis and has demonstrated protective effects against proteinopathy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498d85736cc481a47dc29f1be18d6474
http://europepmc.org/articles/PMC8045925
http://europepmc.org/articles/PMC8045925
Publikováno v:
Experimental eye research. 203
Cataract, the world-leading cause of blindness, is formed when crystallin aggregates cloud the eye lens. We overexpressed PA28αβ, a proteasome activator with properties protective against aggregation and oxidative stress, and examined whether they
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::07513e026fe415d72ebc286149662cc0
https://pubmed.ncbi.nlm.nih.gov/33310056
https://pubmed.ncbi.nlm.nih.gov/33310056
Autor:
Madelene Palmgren, Samo Lasič, Malin Hernebring, Daniel Topgaard, Stefanie Eriksson, Cecilia Geijer, Peter Dahl, Karin Lindkvist-Petersson, Karin Elbing, Jesper S. Hansen
Publikováno v:
The Journal of Membrane Biology
Orthodox aquaporins are transmembrane channel proteins that facilitate rapid diffusion of water, while aquaglyceroporins facilitate the diffusion of small uncharged molecules such as glycerol and arsenic trioxide. Aquaglyceroporins play important rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1120dbc052a9f1f40269124d9a6602c8
http://europepmc.org/articles/PMC5696491
http://europepmc.org/articles/PMC5696491
Autor:
Madeleine Zetterberg, Malin Hernebring, Jaime M. Ross, John Wiseman, Stanley E. Lazic, Julia Adelöf
Publikováno v:
Aging (Albany NY)
Due to strain-specific behavioral idiosyncrasies, inbred mouse strains are suboptimal research models for behavioral aging studies. The aim of this study is to determine age-related behavioral changes of F2 hybrid C57BL/6NxBALB/c male and female mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c5b12af01298aac6d395adb50e4703
https://pubmed.ncbi.nlm.nih.gov/31509518
https://pubmed.ncbi.nlm.nih.gov/31509518
Publikováno v:
Experimental Eye Research. 203:108395
Cataract, the world-leading cause of blindness, is formed when crystallin aggregates cloud the eye lens. We overexpressed PA28αβ, a proteasome activator with properties protective against aggregation and oxidative stress, and examined whether they
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b8defd251cecec5f3a11214eebc9443
https://doi.org/10.1016/j.exer.2020.108395
https://doi.org/10.1016/j.exer.2020.108395
Autor:
Christian Krintel, Karin G. Stenkula, Tatu J K Haataja, Karin Lindkvist-Petersson, Madelene Palmgren, Malin Hernebring, Sebastian Wasserstrom, Urszula Kosinska-Eriksson, Cecilia Holm, Jesper S. Hansen, Helena A. Jones, Sofia de Maré
Publikováno v:
Metabolism: clinical and experimental. 65(12)
Accumulating evidence suggests that dysregulated glycerol metabolism contributes to the pathophysiology of obesity and type 2 diabetes. Glycerol efflux from adipocytes is regulated by the aquaglyceroporin AQP7, which is translocated upon hormone stim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7a7174923adbdf72f85bed4c4ff3aa
https://pubmed.ncbi.nlm.nih.gov/27832861
https://pubmed.ncbi.nlm.nih.gov/27832861
Autor:
Alvar Almstedt, Ellinor Pettersson, Ala Javadi, Elin Johansson Krogh, Malin Hernebring, Åsa Fredriksson, Thomas Nyström
Publikováno v:
Aging Cell. 11:634-643
In organisms with a soma-germ demarcation, the germline must be 'preserved' such that harmful damage is not transmitted to the offspring. Keeping the progeny free of damage may be achieved by gametes enjoying elevated, and/or more functional, homeost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a578f13e69791d0ed865c1947402dd3
https://doi.org/10.1111/j.1474-9726.2012.00823.x
https://doi.org/10.1111/j.1474-9726.2012.00823.x
Autor:
Lucia Micutkova, Pidder Jansen-Dürr, Herbert Lindner, Malin Hernebring, Bettina Sarg, Hermann Unterluggauer, Thomas Nyström
Publikováno v:
Biogerontology. 10:299-309
Cellular senescence is known as a potent mechanism of tumor suppression, and cellular senescence in vitro also reflects at least some features of aging in vivo. The Free Radical Theory of aging suggests that reactive oxygen species are important caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25087fcc8cda94267580f23e860c4285
https://doi.org/10.1007/s10522-008-9193-z
https://doi.org/10.1007/s10522-008-9193-z