Variability in airway inflammation, symptoms, lung function and reliever use in asthma: anti-inflammatory reliever hypothesis and STIFLE study design

Autor: Tim Harrison, Ian D. Pavord, James D. Chalmers, Glenn Whelan, Malin Fagerås, Annika Rutgersson, Laura Belton, Shahid Siddiqui, Per Gustafson

Publikováno v: ERJ Open Research, Vol 6, Iss 2 (2020)

Asthma is a chronic inflammatory airway disease. Increase in airway inflammation is hypothesised to contribute to worsening of asthma symptoms and deterioration in lung function, resulting in the use of reliever medication. Short-acting β2-agonists

Externí odkaz: https://doaj.org/article/20f211cb9ac4460b951a67b66f2a5c1c

Endurance Time During Constant Work Rate Cycle Ergometry in COPD: Development of an Integrated Database From Interventional Studies

Autor: Richard Casaburi, Debora Merrill, Thomas M. Dolmage, Judith Garcia-Aymerich, Malin Fageras, Roger Goldstein, Gale Harding, Nancy Kline Leidy, François Maltais, Denis O’Donnell, Janos Porszasz, Luis Puente-Maestu, Stephen Rennard, Frank Sciurba, Martijn A. Spruit, Ruth Tal-Singer, Kay Tetzlaff, Alex van ’t Hul, Ren Yu, Alan Hamilton

Publikováno v: Chronic Obstr Pulm Dis
Chronic obstructive pulmonary diseases (Miami, Fla.), vol 9, iss 4
Chronic Obstructive Pulmonary Diseases. Journal of the Copd Foundation, 9, 520-537
Chronic Obstructive Pulmonary Diseases : Journal of the COPD Foundation, 9, 4, pp. 520-537
Chronic Obstructive Pulmonary Diseases : Journal of the COPD Foundation, 9(4), 520-537. COPD Foundation

INTRODUCTION: The COPD Biomarkers Qualification Consortium (CBQC) was formed under COPD Foundation management, with the goal of qualifying biomarkers and clinical outcome assessments through established regulatory processes for chronic obstructive pu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cac6ec7758c34e5bfbbc4ea550d636d
https://pubmed.ncbi.nlm.nih.gov/36066494

Reduced risk of clinically important deteriorations by ICS in COPD is eosinophil dependent: a pooled post-hoc analysis

Autor: Mona Bafadhel, Dave Singh, Christine Jenkins, Stefan Peterson, Thomas Bengtsson, Peter Wessman, Malin Fagerås

Publikováno v: Respiratory Research, Vol 21, Iss 1, Pp 1-10 (2020)

Abstract Background Clinically Important Deterioration (CID) is a novel composite measure to assess treatment effect in chronic obstructive pulmonary disease (COPD). We examined the performance and utility of CID in assessing the effect of inhaled co

Externí odkaz: https://doaj.org/article/fb9709e22f4446eb9d72fff30ed2d662

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