Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Malin Dahlgren"'
Autor:
Malin Dahlgren, Barbara Lettiero, Hina Dalal, Kira Mårtensson, Alexander Gaber, Björn Nodin, Sofia K. Gruvberger-Saal, Lao H. Saal, Jillian Howlin
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-9 (2023)
Abstract Objective To investigate CITED1 as a potential biomarker of anti-endocrine response and breast cancer recurrence, given its previously determined role in mediating estrogen-dependant transcription. The study is a continuation of earlier work
Externí odkaz:
https://doaj.org/article/c9c6f678180546e18206439af403ab2a
Autor:
Hina Dalal, Malin Dahlgren, Sergii Gladchuk, Christian Brueffer, Sofia K. Gruvberger-Saal, Lao H. Saal
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Estrogen receptor alpha (ERα, encoded by ESR1) is a well-characterized transcription factor expressed in more than 75% of breast tumors and is the key biomarker to direct endocrine therapies. On the other hand, much less is known about estr
Externí odkaz:
https://doaj.org/article/d4846f6f066d4b8e98d670e12b1413cf
Autor:
Eleonor Olsson, Christof Winter, Anthony George, Yilun Chen, Jillian Howlin, Man‐Hung Eric Tang, Malin Dahlgren, Ralph Schulz, Dorthe Grabau, Danielle van Westen, Mårten Fernö, Christian Ingvar, Carsten Rose, Pär‐Ola Bendahl, Lisa Rydén, Åke Borg, Sofia K Gruvberger‐Saal, Helena Jernström, Lao H Saal
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 8, Pp 1034-1047 (2015)
Abstract Metastatic breast cancer is usually diagnosed after becoming symptomatic, at which point it is rarely curable. Cell‐free circulating tumor DNA (ctDNA) contains tumor‐specific chromosomal rearrangements that may be interrogated in blood p
Externí odkaz:
https://doaj.org/article/c10d86508cf44e4580dc8c94b5230785
Autor:
Malin Dahlgren, Barbara Lettiero, Hina Dalal, Kira Mårtensson, Alexander Gaber, Björn Nodin, Sofia K. Gruvberger-Saal, Lao H. Saal, Jillian Howlin
OBJECTIVE: We present our observations of CITED1 as a potential biomarker of anti-endocrine treatment response and recurrence in breast cancer and suggest that this is dependent on its role in mediating a specific ERα transcriptional response. The s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9b68fe371f298cf63be7f8d9bf76bdf
https://doi.org/10.21203/rs.3.rs-2304366/v1
https://doi.org/10.21203/rs.3.rs-2304366/v1
Small-scale fisheries (SSF) are crucial for food security and poverty alleviation. Many SSF are however under pressure, and in need of better management paying special attention to the key seascape ecosystems which are supporting them. This study inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65580519589848b9cb73deaefe9ff80
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-462448
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-462448
Preexisting Somatic Mutations of Estrogen Receptor Alpha (ESR1) in Early-Stage Primary Breast Cancer
Autor:
Malin, Dahlgren, Anthony M, George, Christian, Brueffer, Sergii, Gladchuk, Yilun, Chen, Johan, Vallon-Christersson, Cecilia, Hegardt, Jari, Häkkinen, Lisa, Rydén, Martin, Malmberg, Christer, Larsson, Sofia K, Gruvberger-Saal, Anna, Ehinger, Niklas, Loman, Åke, Borg, Lao H, Saal
Publikováno v:
JNCI Cancer Spectrum
Background More than three-quarters of primary breast cancers are positive for estrogen receptor alpha (ER; encoded by the gene ESR1), the most important factor for directing anti-estrogenic endocrine therapy (ET). Recently, mutations in ESR1 were id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0ab33fb6fd90c6e2bc89a8586c5040b5
http://europepmc.org/articles/PMC8060794
http://europepmc.org/articles/PMC8060794
Autor:
Lao H. Saal, Jari Häkkinen, Christer Larsson, Cecilia Hegardt, Anna Ehinger, Sofia Gruvberger, Malin Dahlgren, Christian Brueffer, Anthony M. George, Johan Vallon-Christersson, Åke Borg, Sergii Gladchuk, Martin Malmberg, Yilun Chen, Niklas Loman, Lisa Rydén
Publikováno v:
Cancer Research. 80:CT074-CT074
Background: More than three-quarters of primary breast cancers are positive for estrogen receptor alpha (ER; encoded by the gene ESR1), the most important factor for directing anti-estrogenic endocrine therapy. Although mutation in ESR1 is known as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbee69cc58a06bc80b61ca5c78d608d5
https://doi.org/10.1158/1538-7445.am2020-ct074
https://doi.org/10.1158/1538-7445.am2020-ct074
Autor:
Malin Dahlgren, Pär-Ola Bendahl, Therese Törngren, Tamara Tjitrowirjo, Kun Wang, Yilun Chen, Man-Hung Eric Tang, Åke Borg, Christof Winter, Sofia K. Gruvberger-Saal, Dorthe Grabau, Eleonor Olsson, Martin Sjöström, Christian Brueffer, Lao H. Saal, Lisa Rydén, Emma Niméus
Publikováno v:
Oncotarget; 6(35), pp 37169-37184 (2015)
Oncotarget
Oncotarget
To better understand and characterize chromosomal structural variation during breast cancer progression, we enumerated chromosomal rearrangements for 11 patients by performing low-coverage whole-genome sequencing of 11 primary breast tumors and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b4c61d9acad2540a96fee64acb8d30
https://doi.org/10.18632/oncotarget.5951
https://doi.org/10.18632/oncotarget.5951
Autor:
Anna Ehinger, Mårten Fernö, Lisa Rydén, Sara Baker, Sara Alkner, Lao H. Saal, Christof Winter, Malin Dahlgren, Eleonor Olsson, Man-Hung Eric Tang, Yilun Chen, Christian Brueffer, Sofia K. Gruvberger-Saal
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research; 17(1), no 102 (2015)
Breast Cancer Research; 17(1), no 102 (2015)
Introduction By convention, a contralateral breast cancer (CBC) is treated as a new primary tumor, independent of the first cancer (BC1). Although there have been indications that the second tumor (BC2) sometimes may represent a metastatic spread of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbafccbbabe19676cedfaf6e2eff9a54
http://europepmc.org/articles/PMC4531539
http://europepmc.org/articles/PMC4531539
Autor:
Mårten Fernö, Helena Jernström, Malin Dahlgren, Man-Hung Eric Tang, Carsten Rose, Christian Ingvar, Christof Winter, Lisa Rydén, Åke Borg, Eleonor Olsson, Lao H. Saal, Anthony M. George, Sofia K. Gruvberger-Saal, Yilun Chen, Jillian Howlin, Ralph Schulz
Publikováno v:
Cancer Research. 73:LB-77
Malignant cells release into the blood circulation their naked DNA, a potential biomarker containing tumor-specific chromosomal rearrangements. These tumor-derived rearrangements can be detected and quantified in cell-free blood plasma for informatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c846333c234e58a02ef8bbbc0b8fdce
https://doi.org/10.1158/1538-7445.am2013-lb-77
https://doi.org/10.1158/1538-7445.am2013-lb-77