Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Malika Oubaha"'
Autor:
Gaëlle Mawambo, Malika Oubaha, Yusuke Ichiyama, Guillaume Blot, Sergio Crespo-Garcia, Agnieszka Dejda, François Binet, Roberto Diaz-Marin, Christina Sawchyn, Mikhail Sergeev, Rachel Juneau, Randal J. Kaufman, El Bachir Affar, Frédérick A. Mallette, Ariel M. Wilson, Przemyslaw Sapieha
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Cellular adaptation to low oxygen tension triggers primitive pathways that ensure proper cell function. Conditions of hypoxia and low glucose are characteristic of injured tissues and hence successive waves of inflammatory cells must be suit
Externí odkaz:
https://doaj.org/article/43e12a5532544c0686ece219c67a0571
Publikováno v:
Cells, Vol 12, Iss 19, p 2341 (2023)
Cellular senescence, a state of permanent cell cycle arrest in response to endogenous and exogenous stimuli, triggers a series of gradual alterations in structure, metabolism, and function, as well as inflammatory gene expression that nurtures a low-
Externí odkaz:
https://doaj.org/article/1db091ffff94485ba53c34d61a68a139
Autor:
Tracy L. Smith, Malika Oubaha, Gael Cagnone, Cécile Boscher, Jin Sung Kim, Yassine El Bakkouri, Ying Zhang, Rony Chidiac, Jeanne Corriveau, Chantal Delisle, Gregor U. Andelfinger, Przemyslaw Sapieha, Jean-Sébastien Joyal, Jean-Philippe Gratton
Publikováno v:
Cellular and Molecular Life Sciences
The roles of nitric oxide (NO) and endothelial NO synthase (eNOS) in the regulation of angiogenesis are well documented. However, the involvement of eNOS in the sprouting of endothelial tip-cells at the vascular front during sprouting angiogenesis re
Autor:
Khalil Miloudi, Agnieszka Dejda, Przemyslaw Sapieha, Manuel Buscarlet, Katie Bentley, Gael Cagnone, Catherine Ménard, Vera Guber, Bruno Larrivée, Nicolas Tetreault, Malika Oubaha, Agustin Cerani, Flavio A. Rezende, Rony Chidiac, Ariel M. Wilson, Jean-Philippe Gratton, Gaelle Mawambo, Sergio Crespo-Garcia, Jean-Sebastien Joyal, Frédérick A. Mallette, Francois Binet, Chantal Delisle
Publikováno v:
Proceedings of the National Academy of Sciences. 116:4538-4547
Diabetic macular edema is a major complication of diabetes resulting in loss of central vision. Although heightened vessel leakiness has been linked to glial and neuronal-derived factors, relatively little is known on the mechanisms by which mature e
Autor:
Natalija Popovic, Jean-François Daudelin, Vincent De Guire, Ariel M. Wilson, Malika Oubaha, Célia Parinot, Nathalie Labrecque, Salix Boulet, Jean-Sebastien Joyal, Agnieszka Dejda, Gaelle Mawambo, Guillaume Lettre, Florian Sennlaub, Przemyslaw Sapieha, Vanessa Grenier, Frédérique Pilon, Mathieu Laplante, Zhuo Shao, Michel Meunier
Publikováno v:
Science Immunology. 3
Obesity gives rise to metabolic complications by mechanisms that are poorly understood. Although chronic inflammatory signaling in adipose tissue is typically associated with metabolic deficiencies linked to excessive weight gain, we identified a sub
Autor:
Catherine Ménard, Sullivan Henriques, Agnieszka Dejda, Przemyslaw Sapieha, Nathalie Labrecque, Felix Beaudoin, Khalil Miloudi, Flavio A. Rezende, Agustin Cerani, Naoufal Akla, Salix Boulet, Jean-Sébastien Delisle, Malika Oubaha, Gaelle Mawambo, Jean-François Daudelin, Andreas Stahl, Zhuo Shao
Publikováno v:
Journal of Clinical Investigation. 124:4807-4822
Immunological activity in the CNS is largely dependent on an innate immune response and is heightened in diseases, such as diabetic retinopathy, multiple sclerosis, amyotrophic lateral sclerosis, and Alzheimer’s disease. The molecular dynamics gove
Autor:
Marie-Anne Germain, Natalija Popovic, Malika Oubaha, Agnieszka Dejda, Flavio A. Rezende, Khalil Miloudi, Frédérick A. Mallette, Przemyslaw Sapieha, Guillaume Bourdel, Gaelle Mawambo, Randal J. Kaufman, Vera Guber
Publikováno v:
Science Translational Medicine. 8
Pathological angiogenesis is the hallmark of diseases such as cancer and retinopathies. Although tissue hypoxia and inflammation are recognized as central drivers of vessel growth, relatively little is known about the process that bridges the two. In
Autor:
Timothy E. Kennedy, Phuong Trang Nguyen, Ariel M. Wilson, Steve Bourgault, Flavio A. Rezende, Catherine Ménard, Khalil Miloudi, Agustin Cerani, Agnieszka Dejda, Sullivan Henriques, Francois Binet, Przemyslaw Sapieha, Malika Oubaha, Gaelle Mawambo
Diabetic retinopathy (DR) is a major complication of diabetes and a leading cause of blindness in the working-age population. Impaired blood-retinal barrier function leads to macular edema that is closely associated with the deterioration of central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3899275a805e69e14cbbe22aa38df879
https://europepmc.org/articles/PMC4966311/
https://europepmc.org/articles/PMC4966311/
Autor:
Sébastien Thibeault, Brian C. Wilkes, Malika Oubaha, Denis Faubert, Jean-Philippe Gratton, Yohann Rautureau, Chantal Delisle
Publikováno v:
Molecular Cell. 39:468-476
Disruption of adherens junctions between endothelial cells results in compromised endothelial barrier function and in altered angiogenesis. Nitric oxide (NO) produced by endothelial NO synthase (eNOS) is essential for increased vascular permeability
Autor:
Malika Oubaha, Jean-Philippe Gratton
Publikováno v:
Blood. 114:3343-3351
Vascular endothelial growth factor (VEGF) is a potent angiogenic cytokine that also increases vascular permeability. Nitric oxide (NO) released from endothelial cells, after activation of endothelial NO synthase (eNOS), contributes to proangiogenic a