Výsledky vyhledávání - "Malika El Yacoubi"

Antidepressant‐like effect of low dose of scopolamine in the H/Rouen genetic mouse model of depression

Autor: Stéphane Jamain, Malika El Yacoubi, Jean-Marie Vaugeois

Publikováno v: Fundamental & Clinical Pharmacology
Fundamental & Clinical Pharmacology, Wiley, 2020, Online ahead of print. ⟨10.1111/fcp.12639⟩
Fundamental & Clinical Pharmacology, Wiley, 2021, 35 (4), pp.645-649. ⟨10.1111/fcp.12639⟩
Fundamental and Clinical Pharmacology
Fundamental and Clinical Pharmacology, Wiley, 2021, 35 (4), pp.645-649. ⟨10.1111/fcp.12639⟩
Fundamental and Clinical Pharmacology, Wiley, 2020, ⟨10.1111/fcp.12639⟩
Fundamental and Clinical Pharmacology, Wiley, 2020, Online ahead of print. ⟨10.1111/fcp.12639⟩
Fundamental & Clinical Pharmacology, 2020, Online ahead of print. ⟨10.1111/fcp.12639⟩
Fundamental & Clinical Pharmacology, Wiley, 2020, ⟨10.1111/fcp.12639⟩

International audience; Rodent models of depression are useful for the investigation of cellular and neuronal mechanisms of antidepressant drugs and for the discovery of potential new targets. In this study, we examined the antidepressant-like effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611d863b7d985134ce6fae02ac9ac9ac
https://doi.org/10.1111/fcp.12639

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Akademický článek

Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design.

Autor: Jean Mazella, Olivier Pétrault, Guillaume Lucas, Emmanuel Deval, Sophie Béraud-Dufour, Carine Gandin, Malika El-Yacoubi, Catherine Widmann, Alice Guyon, Eric Chevet, Said Taouji, Grégory Conductier, Alain Corinus, Thierry Coppola, Gabriella Gobbi, Jean-Louis Nahon, Catherine Heurteaux, Marc Borsotto

Publikováno v: PLoS Biology, Vol 8, Iss 4, p e1000355 (2010)

Current antidepressant treatments are inadequate for many individuals, and when they are effective, they require several weeks of administration before a therapeutic effect can be observed. Improving the treatment of depression is challenging. Recent

Externí odkaz: https://doaj.org/article/1ce8e5d7cde54153ac1956b5d289c1e1

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Two novel genetic models of major depressive disorders displayheterogeneous sensitivity to treatments

Autor: Malika El Yacoubi, Jean Marie Vaugeois, Stéphane Jamain

Publikováno v: FUND CLIN PHARMACOL
Abstracts of the Annual Meeting of French Society of Pharmacology and Therapeutics
Abstracts of the Annual Meeting of French Society of Pharmacology and Therapeutics, Jun 2019, Lyon, France. pp.PS1-039
HAL

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d29000d306ca04c908e653a1b3e50d4a
https://hal.archives-ouvertes.fr/hal-02390936

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Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses

Autor: Jean-Marie Vaugeois, Nuno J. Machado, Malika El Yacoubi, Inês M. Araújo, Ângelo R. Tomé, Pedro Garção, Ana Isabel Santos, Henrique B. Silva, Ana Paula Ardais, Manuella P. Kaster, Lisiane O. Porciúncula, Rodrigo A. Cunha, Daniela Pochmann, Attila Köfalvi, Ana Patrícia Simões, Paula Agostinho, Catarina Gomes, Diana I Rodrigues

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Caffeine prophylactically prevents mood and memory impairments through adenosine A(2A) receptor (A(2A)R) antagonism. A(2A)R antagonists also therapeutically revert mood and memory impairments, but it is not known if caffeine is also therapeutically o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586e6673c362213fcb72966123c0be08
https://doi.org/10.1007/s12035-016-9774-9

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Post-learning paradoxical sleep deprivation impairs reorganization of limbic and cortical networks associated with consolidation of remote contextual fear memory in mice

Autor: Gaël Malleret, Marius Rosier, David Meunier, Léa Le Barillier, Malika El Yacoubi, Paul-Antoine Salin

Publikováno v: SLEEP
SLEEP, Oxford University Press 2018, 41 (12), ⟨10.1093/sleep/zsy188⟩
Sleep.
Sleep., 2018, 41 (12), ⟨10.1093/sleep/zsy188⟩

Study Objectives Paradoxical sleep (PS) has been shown to play an important role in memory, in particular in emotional memory processes. However, the involvement of this particular sleep stage in the systemic consolidation of remote (30 days old) mem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b476f43afa0be0e469596c241480ad7
https://hal.archives-ouvertes.fr/hal-02369741

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Genetic association between helpless trait and depression-related phenotypes: evidence from crossbreeding studies with H/Rouen and NH/Rouen mice

Autor: Luc Zimmer, J.-M. Vaugeois, Benoit Martin, Malika El Yacoubi, Joëlle Adrien, Michel Hamon, Daniela Popa

Publikováno v: International Journal of Neuropsychopharmacology
International Journal of Neuropsychopharmacology, 2011, 15 (3), pp.363-374. ⟨10.1017/S1461145711000605⟩
International Journal of Neuropsychopharmacology, Oxford University Press (OUP), 2011, 15 (3), pp.363-374. ⟨10.1017/S1461145711000605⟩

Genetic factors are believed to be involved in the aetiology of unipolar depressive disorders. We have previously described a model built up by selective breeding of mice with different responses in the tail suspension test, a screening test for pote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4336e9e35360d8ded5d6e0a1e51bd7a4
https://doi.org/10.1017/s1461145711000605

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Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A

Autor: Nuno J, Machado, Ana Patrícia, Simões, Henrique B, Silva, Ana Paula, Ardais, Manuella P, Kaster, Pedro, Garção, Diana I, Rodrigues, Daniela, Pochmann, Ana Isabel, Santos, Inês M, Araújo, Lisiane O, Porciúncula, Ângelo R, Tomé, Attila, Köfalvi, Jean-Marie, Vaugeois, Paula, Agostinho, Malika, El Yacoubi, Rodrigo A, Cunha, Catarina A, Gomes

Publikováno v: Molecular neurobiology. 54(2)

Caffeine prophylactically prevents mood and memory impairments through adenosine A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::247c11c8fccc7f96cd746406ecbbbefe
https://pubmed.ncbi.nlm.nih.gov/26860412

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Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype

Autor: Catherine Heurteaux, Nicolas Guy, Malika El Yacoubi, Susanne Thümmler, Guillaume Lucas, Jean-Marie Vaugeois, Nicolas Blondeau, Marc Borsotto, Guy Debonnel, Xiao-Dong Peng, Gabriella Gobbi, Michel Lazdunski, Catherine Widmann, Florence Noble

Publikováno v: Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2006, 9, pp.1134-1141
Nature Neuroscience, Nature Publishing Group, 2006, 9, pp.1134-1141. ⟨10.1038/nn1749⟩

Depression is a devastating illness with a lifetime prevalence of up to 20%. The neurotransmitter serotonin or 5-hydroxytryptamine (5-HT) is involved in the pathophysiology of depression and in the effects of antidepressant treatments. However, molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad4b171a119014b7a694ac1dbfb3dba
https://doi.org/10.1038/nn1749

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A chronic treatment with fluoxetine decreases 5-HT1A receptors labeling in mice selected as a genetic model of helplessness

Autor: Jean Costentin, Isabelle Leroux-Nicollet, Jean-Marie Vaugeois, Malika El Yacoubi, Laurent Naudon

Publikováno v: Brain Research
Brain Research, Elsevier, 2002, 936 (1-2), pp.68-75. ⟨10.1016/S0006-8993(02)02548-9⟩

Two lines of mice were bred for their opposite helpless behavior in the tail suspension test, i.e., helpless (HL) mice and non helpless (NHL) mice. The 5-HT(1A) receptor labeling was quantified by means of autoradiography with (3)H-8-OH-DPAT on brain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb0bbbaeac863c4c26bbff6db139327
https://doi.org/10.1016/s0006-8993(02)02548-9

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GABAB(1) receptor subunit isoforms differentially regulate stress resilience

Autor: Olivia F. O’Leary, Timothy G. Dinan, Hélène M. Savignac, John F. Cryan, Jean-Marie Vaugeois, Javier A. Bravo, Martin Gassmann, Malika El Yacoubi, Daniela Felice, Bernhard Bettler, Tadhg Crowley, Stefano Galimberti

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (42), pp.15232-7. ⟨10.1073/pnas.1404090111⟩
Adademy of Sciences of the USA
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (42), pp.15232-7. ⟨10.1073/pnas.1404090111⟩

International audience; Stressful life events increase the susceptibility to developing psychiatric disorders such as depression; however, many individuals are resilient to such negative effects of stress. Determining the neurobiology underlying this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149c1dcab6972f5777ec07f51aacbd52
https://europepmc.org/articles/PMC4210293/

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