Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Malika, Aid"'
Autor:
Malika Aid, Kathryn E. Stephenson, Ai-ris Y. Collier, Joseph P. Nkolola, James V. Michael, Steven E. McKenzie, Dan H. Barouch
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Thrombosis with thrombocytopenia syndrome (TTS) is a rare but potentially severe adverse event following immunization with adenovirus vector-based COVID-19 vaccines such as Ad26.COV2.S (Janssen) and ChAdOx1 (AstraZeneca). However, no case of
Externí odkaz:
https://doaj.org/article/9e0279f50cd949b9be8538aa12037484
Autor:
Samuel J. Vidal, Daniel Sellers, Jingyou Yu, Shoko Wakabayashi, Jaimie Sixsmith, Malika Aid, Julia Barrett, Sage F. Stevens, Xiaowen Liu, Wenjun Li, Courtney R. Plumlee, Kevin B. Urdahl, Amanda J. Martinot, Dan H. Barouch
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106963- (2023)
Summary: Bacillus Calmette–Guérin (BCG) remains the only approved tuberculosis (TB) vaccine despite limited efficacy. Preclinical studies of next-generation TB vaccines typically use a murine aerosol model with a supraphysiologic challenge dose. H
Externí odkaz:
https://doaj.org/article/b3c8b12162af49ab8b180e105b37998b
Autor:
Justin Harper, Susan P. Ribeiro, Chi Ngai Chan, Malika Aid, Claire Deleage, Luca Micci, Maria Pino, Barbara Cervasi, Gopalan Raghunathan, Eric Rimmer, Gulesi Ayanoglu, Guoxin Wu, Neeta Shenvi, Richard J.O. Barnard, Gregory Q. Del Prete, Kathleen Busman-Sahay, Guido Silvestri, Deanna A. Kulpa, Steven E. Bosinger, Kirk A. Easley, Bonnie J. Howell, Dan Gorman, Daria J. Hazuda, Jacob D. Estes, Rafick-Pierre Sekaly, Mirko Paiardini
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 8 (2022)
Interleukin-10 (IL-10) is an immunosuppressive cytokine that signals through STAT3 to regulate T follicular helper (Tfh) cell differentiation and germinal center formation. In SIV-infected macaques, levels of IL-10 in plasma and lymph nodes (LNs) wer
Externí odkaz:
https://doaj.org/article/3c551d2d1a814a3d84819bbd3a685652
Autor:
Malika Aid, Samuel J Vidal, Cesar Piedra-Mora, Sarah Ducat, Chi N Chan, Stephen Bondoc, Alessandro Colarusso, Carly E Starke, Michael Nekorchuk, Kathleen Busman-Sahay, Jacob D Estes, Amanda J Martinot, Dan H Barouch
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1009990 (2022)
Syrian golden hamsters exhibit features of severe disease after SARS-CoV-2 WA1/2020 challenge and are therefore useful models of COVID-19 pathogenesis and prevention with vaccines. Recent studies have shown that SARS-CoV-2 infection stimulates type I
Externí odkaz:
https://doaj.org/article/16f32ce880f94c6d88ec71d28dacb9ec
Autor:
Raja Mohan Gopalakrishnan, Malika Aid, Noe B. Mercado, Caitlin Davis, Shaily Malik, Emma Geiger, Valerie Varner, Rhianna Jones, Steven E. Bosinger, Cesar Piedra-Mora, Amanda J. Martinot, Dan H. Barouch, R. Keith Reeves, C. Sabrina Tan
Publikováno v:
JCI Insight, Vol 6, Iss 20 (2021)
Knowledge of immune activation in the brain during acute HIV infection is crucial for the prevention and treatment of HIV-associated neurological disorders. We determined regional brain (basal ganglia, thalamus, and frontal cortex) immune and virolog
Externí odkaz:
https://doaj.org/article/a869258e8da0486a85f240faebc9c307
Autor:
Amanda J Martinot, Eryn Blass, Jingyou Yu, Malika Aid, Shant H Mahrokhian, Sara B Cohen, Courtney R Plumlee, Rafael A Larocca, Noman Siddiqi, Shoko Wakabayashi, Michelle Gardner, Rebecca Audette, Anne Devorak, Kevin B Urdahl, Eric J Rubin, Dan H Barouch
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009096 (2020)
Bacille Calmette-Guerin (BCG), an attenuated whole cell vaccine based on Mycobacterium bovis, is the only licensed vaccine against Mycobacterium tuberculosis (Mtb), but its efficacy is suboptimal and it fails to protect against pulmonary tuberculosis
Externí odkaz:
https://doaj.org/article/5618c6f81d13453f82e4f2111c2896a8
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Natural killer (NK) cells are crucial regulators of antiviral and anti-tumor immune responses. Although in humans some NK cell transcriptional programs are relatively well-established, NK cell transcriptional networks in non-human primates (NHP) rema
Externí odkaz:
https://doaj.org/article/6a3276e44db947d4848943b14ae29095
Autor:
Lawrence J Tartaglia, Alexander Badamchi-Zadeh, Peter Abbink, Eryn Blass, Malika Aid, Makda S Gebre, Zhenfeng Li, Kevin Clyde Pastores, Sebastien Trott, Siddhant Gupte, Rafael A Larocca, Dan H Barouch
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008180 (2019)
Adenoviral vectors have shown significant promise as vaccine delivery vectors due to their ability to elicit both innate and adaptive immune responses. α-defensins are effector molecules of the innate immune response and have been shown to modulate
Externí odkaz:
https://doaj.org/article/93ca8d90867841dd915bf6f9a69e7da7
Autor:
David DeWolfe, Malika Aid, Kevin McGann, Joshua Ghofrani, Emma Geiger, Catherine Helzer, Shaily Malik, Steve Kleiboeker, Stephanie Jost, Chen Sabrina Tan
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: A previously proposed immune risk profile (IRP), based on T cell phenotype and CMV serotype, is associated with mortality in the elderly and increased infections post-kidney transplant. To evaluate if NK cells contribute to the IRP and if
Externí odkaz:
https://doaj.org/article/6d32fbec712840629892ea2b3805b8d8
Autor:
Samuel J. Vidal, Daniel Sellers, Jingyou Yu, Shoko Wakabayashi, Jaimie Sixsmith, Malika Aid, Julia Barrett, Sage F. Stevens, Xiaowen Liu, Wenjun Li, Courtney R. Plumlee, Kevin B. Urdahl, Amanda J. Martinot, Dan H. Barouch
Bacillus Calmette–Guérin (BCG) remains the only clinically approved tuberculosis (TB) vaccine despite limited efficacy. Preclinical studies of next generation TB vaccines have typically used a murine aerosol challenge model that employs a high sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3c49746640785b2b3dec277ce287112
https://doi.org/10.1101/2023.03.17.533226
https://doi.org/10.1101/2023.03.17.533226
