Efficacy and safety of ivermectin for the treatment of Plasmodium falciparum infections in asymptomatic male and female Gabonese adults – a pilot randomized, double-blind, placebo-controlled single-centre phase Ib/IIa clinical trialResearch in context

Autor: Dorothea Ekoka Mbassi, Ghyslain Mombo-Ngoma, Jana Held, Dearie Glory Okwu, Wilfrid Ndzebe-Ndoumba, Laura Charlotte Kalkman, Franck Aurelien Ekoka Mbassi, Lais Pessanha de Carvalho, Juliana Inoue, Malik Azeez Akinosho, Lia Betty Dimessa Mbadinga, Emmanuel Koffi Yovo, Benjamin Mordmüller, Peter Gottfried Kremsner, Ayôla Akim Adegnika, Michael Ramharter, Rella Zoleko-Manego

Publikováno v: EBioMedicine, Vol 97, Iss , Pp 104814- (2023)

Summary: Background: Ivermectin's mosquitocidal effect and in vitro activity against Plasmodium falciparum asexual stages are known. Its in vivo blood-schizonticidal efficacy is unknown. Ivermectin's tolerability and efficacy against P. falciparum in

Externí odkaz: https://doaj.org/article/8ce2e823086b4bb9a68dd5d3ee383551

Prevalence, risk factors and character of abdominal hernia in Arar City, Northern Saudi Arabia in 2017

Autor: Abdulmajeed AhmedAlenazi, Mahmoud Mohammed Alsharif, Malik Azhar Hussain, Naif Gharbi Alenezi, Abdulrhman Ahmed Alenazi, Shouq Amjad Almadani, Nour Homoud

Publikováno v: Electronic Physician, Vol 9, Iss 7, Pp 4806-4811 (2017)

Background: Abdominal wall hernias are a very common surgical condition affecting all ages and both sexes. The main risk factors of hernias include pregnancy, weight lifting, constipation, and weight gain. Objective: The aim of this study was to de

Externí odkaz: https://doaj.org/article/27a8e70d9bfc424eacadc6104623e792

Study of the destructive activity of microorganisms isolated from soil contaminated by pesticides

Autor: Malik Azhar, Abdieva Gulzhamal, Ualieva Perizat, Akimbekov Nuraly

Publikováno v: E3S Web of Conferences, Vol 122, p 05007 (2019)

Chemical pollution of natural and agricultural habitats is a growing global problem and a serious threat to the sustainability and health of people. Among various chemical ecotoxicants of anthropogenic origin, organochlorine pesticides are among the

Externí odkaz: https://doaj.org/article/1507418faf304318b80e29117d13c5be

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Vaccine effectiveness against SARS-CoV-2 infection or COVID-19 hospitalization with the Alpha, Delta, or Omicron SARS-CoV-2 variant: A nationwide Danish cohort study.

Autor: Gram MA; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Emborg HD; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Schelde AB; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Friis NU; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Nielsen KF; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Moustsen-Helms IR; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Legarth R; Division of Infectious Disease Preparedness, Data Integration and Analysis, Statens Serum Institut, Copenhagen, Denmark., Lam JUH; Division of Infectious Disease Preparedness, Data Integration and Analysis, Statens Serum Institut, Copenhagen, Denmark., Chaine M; Division of Infectious Disease Preparedness, Data Integration and Analysis, Statens Serum Institut, Copenhagen, Denmark., Malik AZ; Division of Infectious Disease Preparedness, Data Integration and Analysis, Statens Serum Institut, Copenhagen, Denmark., Rasmussen M; Department of Virus Research and Development Laboratory, Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark., Fonager J; Department of Virus Research and Development Laboratory, Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark., Sieber RN; Department of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark., Stegger M; Department of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark., Ethelberg S; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.; Department of Public Health, Global Health Section, University of Copenhagen, Copenhagen, Denmark., Valentiner-Branth P; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Hansen CH; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.; MRC International Statistics and Epidemiology Group, Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Publikováno v: PLoS medicine [PLoS Med] 2022 Sep 01; Vol. 19 (9), pp. e1003992. Date of Electronic Publication: 2022 Sep 01 (Print Publication: 2022).