Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Maliha, Sarfraz"'
Autor:
Hayat Ullah, Imad Uddin, Hafeeza Zafar Ali, Wagma Hassan, Gul Mehnaz, Laiba Maryam, Maliha Sarfraz, Muhammad Saleem Khan, Mohammad Shahidul Islam, Zainab M. Almarhoon, Rashid Iqbal, Muhammad Nabi
Publikováno v:
Results in Chemistry, Vol 11, Iss , Pp 101832- (2024)
The present study reports the design and synthesis of new benzimidazole-oxadiazole compounds as potent inhibitors of α-glucosidase and α-amylase. The synthesized molecules were characterized through different techniques such as 1HNMR, 13CNMR, HREI-
Externí odkaz:
https://doaj.org/article/46a3d651ca70488f87d9b223a885ddee
Autor:
Sundas Tariq, Fazal Rahim, Hayat Ullah, Maliha Sarfraz, Rafaqat Hussain, Shoaib Khan, Misbah Ullah Khan, Wajid Rehman, Amjad Hussain, Mashooq Ahmad Bhat, Muhammad Kamran Farooqi, Syed Adnan Ali Shah, Naveed Iqbal
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 410 (2024)
Benzimidazole-based pyrrole/piperidine analogs (1–26) were synthesized and then screened for their acetylcholinesterase and butyrylcholinesterase activities. All the analogs showed good to moderate cholinesterase activities. Synthesized compounds (
Externí odkaz:
https://doaj.org/article/9b3eb65368d14b0aafb27989d703e974
Autor:
Rafaqat Hussain, Fazal Rahim, Hayat Ullah, Shoaib Khan, Maliha Sarfraz, Rashid Iqbal, Faiza Suleman, Mohammad Khalid Al-Sadoon
Publikováno v:
Molecules, Vol 28, Iss 20, p 7015 (2023)
Alzheimer’s disease (AD) is a degenerative neurological condition that severely affects the elderly and is clinically recognised by a decrease in cognition and memory. The treatment of this disease has drawn considerable attention and sparked incre
Externí odkaz:
https://doaj.org/article/d1abdcd27af642ccbd2a8fe3f21074eb
Autor:
Ghulam Nabi, Shahid Ahmad, Sana Ullah, Sahib Zada, Maliha Sarfraz, Xinle Guo, Muhammad Ismail, Kunyuan Wanghe
Publikováno v:
Journal of King Saud University: Science, Vol 34, Iss 4, Pp 102006- (2022)
Microplastics (MPs), an emerging ubiquitous pollutant in the aquatic ecosystem, pose serious health concerns to the survival of aquatic fauna, especially top predators (e.g., aquatic mammals). It is challenging to investigate the toxicological profil
Externí odkaz:
https://doaj.org/article/4597afae3ab64272926806823a1a45b2
Autor:
Shoaib Khan, Hayat Ullah, Muhammad Taha, Fazal Rahim, Maliha Sarfraz, Rashid Iqbal, Naveed Iqbal, Rafaqat Hussain, Syed Adnan Ali Shah, Khurshid Ayub, Marzough Aziz Albalawi, Mahmoud A. Abdelaziz, Fatema Suliman Alatawi, Khalid Mohammed Khan
Publikováno v:
Molecules, Vol 28, Iss 2, p 559 (2023)
Alzheimer’s disease is a major public brain condition that has resulted in many deaths, as revealed by the World Health Organization (WHO). Conventional Alzheimer’s treatments such as chemotherapy, surgery, and radiotherapy are not very effective
Externí odkaz:
https://doaj.org/article/26f9abc65a2b41108557969c173f60fb
Autor:
Fazal Rahim, Hayat Ullah, Muhammad Taha, Rafaqat Hussain, Maliha Sarfraz, Rashid Iqbal, Naveed Iqbal, Shoaib Khan, Syed Adnan Ali Shah, Marzough Aziz Albalawi, Mahmoud A. Abdelaziz, Fatema Suliman Alatawi, Abdulrahman Alasmari, Mohamed I. Sakran, Nahla Zidan, Ibrahim Jafri, Khalid Mohammed Khan
Publikováno v:
Molecules, Vol 28, Iss 1, p 21 (2022)
Triazole-based thiosemicarbazone derivatives (6a–u) were synthesized then characterized by spectroscopic techniques, such as 1HNMR and 13CNMR and HRMS (ESI). Newly synthesized derivatives were screened in vitro for inhibitory activity against acety
Externí odkaz:
https://doaj.org/article/9d33bb5934d442898033473af515badd
Publikováno v:
Endocrine and Metabolic Science, Vol 4, Iss , Pp 100098- (2021)
Background: Diabetes is now a global problem and millions of people are suffering all over the world. Reports exist for the allopathic use of turmeric, black pepper, and date palm as an antidiabetic and antioxidant agent. Aim: The current study was d
Externí odkaz:
https://doaj.org/article/b264ee62cc5348c483b6830082004512
Autor:
Hayat Ullah, Shoaib Khan, Fazal Rahim, Muhammad Taha, Rashid Iqbal, Maliha Sarfraz, Syed Adnan Ali Shah, Muhammad Sajid, Mohamed F. Awad, Awatif Omran, Marzough Aziz Albalawi, Mahmoud A. Abdelaziz, Azza Al Areefy, Ibrahim Jafri
Publikováno v:
Molecules, Vol 27, Iss 20, p 6921 (2022)
Diabetes mellitus is one of the most chronic metabolic diseases. In the past few years, our research group has synthesized and evaluated libraries of heterocyclic analogs against α-glucosidase and α-amylase enzymes and found encouraging results. Th
Externí odkaz:
https://doaj.org/article/d44c5e8ff2ce41f89253429c86a2c56d
Autor:
Rafaqat Hussain, Hayat Ullah, Fazal Rahim, Maliha Sarfraz, Muhammad Taha, Rashid Iqbal, Wajid Rehman, Shoaib Khan, Syed Adnan Ali Shah, Sajjad Hyder, Majid Alhomrani, Abdulhakeem S. Alamri, Osama Abdulaziz, Mahmoud A. Abdelaziz
Publikováno v:
Molecules, Vol 27, Iss 18, p 6087 (2022)
Twenty-four analogues of benzimidazole-based thiazoles (1–24) were synthesized and assessed for their in vitro acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitory potential. All analogues were found to exhibit good inhibitory p
Externí odkaz:
https://doaj.org/article/91f1d9197c324f698fa33fddb866263f
Publikováno v:
Saudi Pharmaceutical Journal, Vol 25, Iss 4, Pp 449-452 (2017)
The aim of the present study was to investigate the effects of aqueous extract of black pepper and ajwa seed on liver enzymes in alloxan-induced diabetic Wister albino rats to show the preventive and ameliorating effects in hyperglycemic rats. Rats w
Externí odkaz:
https://doaj.org/article/80248cde57a84656923b9deb927f4626