Zobrazeno 1 - 10
of 1 313
pro vyhledávání: '"Malignant phenotype"'
Autor:
Zhidong Huang, Kaixin Lou, Mengyang Qi, Jinhui Wang, Linwei Li, Bo Sun, Chen Wang, Xirui Zhou, Debo Chen, Hong Liu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Currently, there is a lack of biomarkers to identify breast cancer (BC) patients who would benefit from CDK4/6 inhibitors. This study combined machine learning (ML) algorithms based on transcriptomic data with both in vivo and in
Externí odkaz:
https://doaj.org/article/9a7d5eea1e1c477ea592e45205347318
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Epithelial-mesenchymal transition (EMT) plays an important role in malignant progression of Triple-negative breast cancer (TNBC). Many studies have confirmed that miRNA-200c-3p is related to EMT. And we found that it is involved in the regul
Externí odkaz:
https://doaj.org/article/cf8448dc4fe747f8ad698e0e7f4cb1d7
Publikováno v:
European Journal of Case Reports in Internal Medicine (2024)
Mitral valve prolapse (MVP) is a primary valvular disease of the mitral valve with a prevalence of 2.4% of the general population. Valve abnormalities range from simple fibroelastic deficiency of the leaflets to diffuse myxomatous degenerative change
Externí odkaz:
https://doaj.org/article/c8a406bd114c4cf1b1242101d4f7c6d6
Autor:
Kensuke Tateishi, Yohei Miyake, Taishi Nakamura, Hiromichi Iwashita, Takahiro Hayashi, Akito Oshima, Hirokuni Honma, Hiroaki Hayashi, Kyoka Sugino, Miyui Kato, Kaishi Satomi, Satoshi Fujii, Takashi Komori, Tetsuya Yamamoto, Daniel P. Cahill, Hiroaki Wakimoto
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract In IDH-mutant astrocytoma, IDH2 mutation is quite rare and biological mechanisms underlying tumor progression in IDH2-mutant astrocytoma remain elusive. Here, we report a unique case of IDH2 mutant astrocytoma, CNS WHO grade 3 that developed
Externí odkaz:
https://doaj.org/article/bbe8b7243e7e40e29827ce3987261302
Autor:
Dongcheng Xie, Hailong Huang, Youwei Guo, Zhipeng Jiang, Yirui Kuang, Haoxuan Huang, Weidong Liu, Lei Wang, Zhaoqi Xin, Binbin Wang, Caiping Ren, Xingjun Jiang
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26976- (2024)
Background: Glioma, a highly resistant and recurrent type of central nervous system tumor, poses a significant challenge in terms of effective drug treatments and its associated mortality rates. Despite the discovery of Ferredoxin 1 (FDX1) as a cruci
Externí odkaz:
https://doaj.org/article/b3319e3d0dc24d55b66135e58fd1679d
Autor:
Zhen-Fei Zhang, Fang Liu, Han-Rong Zhang, Bing Liu, Shu-Qian Zheng, Wan-Qian Ye, Jia-Nan Ding, Ze-Jie Zhou, Hui-Xian Luo, Fang Wu, Xuan-Min Guo, Jue-Yu Zhou, Yong-Hui Guo
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Objective Recent studies indicated that transmembrane protein 40 (TMEM40) is associated with several types of cancers but is not clear in cervical cancer (CC). The study aimed to examine the role of TMEM40 in CC and related mechanisms. Metho
Externí odkaz:
https://doaj.org/article/382d5425a0d042c7b8964f5dfd15c524
Autor:
Nadine Wehbe, Adnan Badran, Serine Baydoun, Ali Al-Sawalmih, Marc Maresca, Elias Baydoun, Joelle Edward Mesmar
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 726 (2024)
Natural remedies have been indispensable to traditional medicine practices for generations, offering therapeutic solutions for various ailments. In modern times, these natural products continue to play a pivotal role in the discovery of new drugs, es
Externí odkaz:
https://doaj.org/article/5b54780056494ac48e7b660fd9e8e718
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundTumor Protein D52-Like 2 (TPD52L2) is a tumor-associated protein that participates in B-cell differentiation. However, the role of TPD52L2 in the pathological process of clear cell renal cell carcinoma (ccRCC) is unclear.MethodsMultiple omi
Externí odkaz:
https://doaj.org/article/163c34b1af4f42e68bfbc9bb95a4f978
Autor:
Chao Tu, Binfeng Liu, Chenbei Li, Chengyao Feng, Hua Wang, Haixia Zhang, Shasha He, Zhihong Li
Publikováno v:
MedComm, Vol 4, Iss 5, Pp n/a-n/a (2023)
Abstract Soft tissue sarcoma (STS) is an uncommon malignancy that often carries a grim prognosis. Trophinin‐associated protein (TROAP) is augmented in a variety of tumors and can affect tumor proliferation. Nevertheless, the prognostic value and sp
Externí odkaz:
https://doaj.org/article/74e7d93572674c33bea51b108e57e9a6
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