Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Malia B, Potts"'
Autor:
Jung Mi Park, Seung Wook Yang, Wei Zhuang, Asim K Bera, Yan Liu, Deepak Gurbani, Sergei J von Hoyningen-Huene, Sadie Miki Sakurada, Haiyun Gan, Shondra M Pruett-Miller, Kenneth D Westover, Malia B Potts
Publikováno v:
PLoS Biology, Vol 19, Iss 6, p e3001281 (2021)
Nutrient-responsive protein kinases control the balance between anabolic growth and catabolic processes such as autophagy. Aberrant regulation of these kinases is a major cause of human disease. We report here that the vertebrate nonreceptor tyrosine
Externí odkaz:
https://doaj.org/article/4164afef6c64473eae9b0a547aaea3fd
Autor:
Malia B, Potts
Publikováno v:
Cell Chemical Biology. 29:1569-1571
In this issue of Cell Chemical Biology, You et al. demonstrate that selective degradation of ERK5 exhibits neither anti-proliferative nor anti-inflammatory activities previously attributed to ERK5 inactivation. This settles a longstanding debate in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b252f54282ec67a8fb49eec47223d15
https://doi.org/10.1016/j.chembiol.2022.11.002
https://doi.org/10.1016/j.chembiol.2022.11.002
Autor:
Swarna, Beesetti, Shyam, Sirasanagandla, Sadie Miki, Sakurada, Shondra M, Pruett-Miller, Rhea, Sumpter, Beth, Levine, Malia B, Potts
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1868:166453
Fanconi anemia (FA) is the most common inherited bone marrow failure syndrome. The FA proteins have functions in genome maintenance and in the cytoplasmic process of selective autophagy, beyond their canonical roles of repairing DNA interstrand cross
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45ca2a304842c8e4615a3c99e4f4fe9
https://doi.org/10.1016/j.bbadis.2022.166453
https://doi.org/10.1016/j.bbadis.2022.166453
Autor:
Shondra M. Pruett-Miller, Malia B. Potts, Yan Liu, Sadie Miki Sakurada, Asim K. Bera, Sergei J. von Hoyningen-Huene, Kenneth D. Westover, Deepak Gurbani, Haiyun Gan, Wei Zhuang, Jung Mi Park, Seung Wook Yang
Publikováno v:
PLoS Biology, Vol 19, Iss 6, p e3001281 (2021)
PLoS Biology
PLoS Biology
Nutrient-responsive protein kinases control the balance between anabolic growth and catabolic processes such as autophagy. Aberrant regulation of these kinases is a major cause of human disease. We report here that the vertebrate nonreceptor tyrosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d14255d08b0e169bebabf712a73308f
https://doaj.org/article/4164afef6c64473eae9b0a547aaea3fd
https://doaj.org/article/4164afef6c64473eae9b0a547aaea3fd
Autor:
Malia B. Potts, Taotao Ling, Jane E. Craig, Julie Maier, Travis D. Marsico, John C. Bollinger, Fatima Rivas, Joseph T. Opferman, Walter H. Lang, Amit Budhraja
Publikováno v:
Journal of Natural Products. 82:1301-1311
Natural products continue to provide a platform to study biological systems. A bioguided study of cancer cell models led us to a new member of the jatrophane natural products from Jatropha gossypiifolia, which was independently identified and charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bae6e9d69801979c47aa58a128b32c6
https://doi.org/10.1021/acs.jnatprod.8b01087
https://doi.org/10.1021/acs.jnatprod.8b01087
Autor:
Taotao Ling, Zoran Rankovic, Fatima Rivas, Malia B. Potts, Sourav Das, Amit Budhraja, Julie Maier, Joseph T. Opferman, Anang A. Shelat, Rachel Bassett
Publikováno v:
European Journal of Medicinal Chemistry. 164:391-398
Although pediatric leukemia is generally treatable, certain leukemic subtypes face poor prognosis in the clinic suggesting new selective therapeutic agents are needed. Thus, to identify selective apoptosis inducers, a small-molecule library screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e979fa4af6071bb3cd18e0c0787d7c9f
https://doi.org/10.1016/j.ejmech.2018.12.059
https://doi.org/10.1016/j.ejmech.2018.12.059
Publikováno v:
Marine Drugs, Vol 15, Iss 3, p 75 (2017)
Chemicals found in nature have evolved over geological time scales to productively interact with biological molecules, and thus represent an effective resource for pharmaceutical development. Marine-derived bacteria are rich sources of chemically div
Externí odkaz:
https://doaj.org/article/f4f5598e9eed4b1e82f6d6c4ced51029
Autor:
Zhenya Hong, Jane E. Craig, Taosheng Chen, Lily Jun Shen Huang, Wei Zhuang, Gamze B. Bulut, Sadie Miki Sakurada, Jonathan Low, Malia B. Potts, Jamshid Temirov, Joseph N. Miller, Raju R. Rayavarapu, Shondra M. Pruett-Miller
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 6, Iss 1, Pp 1-13 (2020)
Cell Death Discovery, Vol 6, Iss 1, Pp 1-13 (2020)
Mitochondria are vital organelles that coordinate cellular energy homeostasis and have important roles in cell death. Therefore, the removal of damaged or excessive mitochondria is critical for maintaining proper cellular function. The PINK1-Parkin p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e35506dd5c5cc74f18ba5897b121cc5
https://pubmed.ncbi.nlm.nih.gov/33101709
https://pubmed.ncbi.nlm.nih.gov/33101709
Publikováno v:
Clinical Cancer Research. 26:PO-069
Background: The non-receptor tyrosine kinase, SRMS (Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristoylation sites) is a member of the BRK family kinases (BFKs) that represents an evolutionarily conserved relative of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6f5f7accb32f4e104a18e92adcce248
https://doi.org/10.1158/1557-3265.covid-19-po-069
https://doi.org/10.1158/1557-3265.covid-19-po-069
Autor:
Patrick Ryan Potts, Jenny L. Weon, Saumya Ramanathan, Michael A. White, Yi Hung Ou, Malia B. Potts, Klementina Fon Tacer, Carlos T. Pineda
Publikováno v:
Cell. 160(4):715-728
SummaryAMP-activated protein kinase (AMPK) is a master sensor and regulator of cellular energy status. Upon metabolic stress, AMPK suppresses anabolic and promotes catabolic processes to regain energy homeostasis. Cancer cells can occasionally suppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fb19707572d8e35c2e355d47849e43