Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Mali Camberis"'
Autor:
Haozhe Wang, Kristian Barry, Aidil Zaini, Gillian Coakley, Mati Moyat, Carmel P Daunt, Lakshanie C Wickramasinghe, Rossana Azzoni, Roxanne Chatzis, Bibek Yumnam, Mali Camberis, Graham Le Gros, Olaf Perdijk, Jaime P P Foong, Joel C Bornstein, Benjamin J Marsland, Nicola L Harris
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1011766 (2024)
Intestinal helminth infection triggers a type 2 immune response that promotes a 'weep-and sweep' response characterised by increased mucus secretion and intestinal hypermotility, which function to dislodge the worm from its intestinal habitat. Recent
Externí odkaz:
https://doaj.org/article/36ebdfe1069a4be6ad32d6752f7b22f2
Autor:
Francesco Vacca, Thomas C. Mules, Mali Camberis, Brittany Lavender, Sophia-Louise Noble, Alissa Cait, Kate Maclean, John Mamum, Bibek Yumnam, Tama Te Kawa, Laura Ferrer-Font, Jeffry S. Tang, Olivier Gasser, Graham Le Gros, Stephen Inns
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Infecting humans with controlled doses of helminths, such as human hookworm (termed hookworm therapy), is proposed to prevent or treat various intestinal and extraintestinal diseases. However, full-scale clinical trials examining hookworm therapy are
Externí odkaz:
https://doaj.org/article/e61ec8e7ee5a427daf2814737aff4cf8
Autor:
David Eccles, Jodie Chandler, Mali Camberis, Bernard Henrissat, Sergey Koren, Graham Le Gros, Jonathan J. Ewbank
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-18 (2018)
Abstract Background Eukaryotic genome assembly remains a challenge in part due to the prevalence of complex DNA repeats. This is a particularly acute problem for holocentric nematodes because of the large number of satellite DNA sequences found throu
Externí odkaz:
https://doaj.org/article/c7a1fbd8e741419ebac5dcd9a66a6496
Autor:
Christophe Pellefigues, Palak Mehta, Melanie Sarah Prout, Karmella Naidoo, Bibek Yumnam, Jodie Chandler, Sally Chappell, Kara Filbey, Mali Camberis, Graham Le Gros
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Basophils are granulocytes involved in parasite immunity and allergic diseases, known for their potent secretion of type 2 cytokines. Identifying their functions has proven to be controversial due to their relative rarity and their complex lineage ph
Externí odkaz:
https://doaj.org/article/4f9755fc5097464a9ad630d364947b4c
Autor:
Tiffany Bouchery, Kara Filbey, Amy Shepherd, Jodie Chandler, Deepa Patel, Alfonso Schmidt, Mali Camberis, Adeline Peignier, Adam A T Smith, Karen Johnston, Gavin Painter, Mark Pearson, Paul Giacomin, Alex Loukas, Maria-Elena Bottazzi, Peter Hotez, Graham LeGros
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006931 (2018)
As part of on-going efforts to control hookworm infection, the "human hookworm vaccine initiative" has recognised blood feeding as a feasible therapeutic target for inducing immunity against hookworm infection. To this end, molecular approaches have
Externí odkaz:
https://doaj.org/article/4cf8b5ab6792453da2f872e631b2dec6
Autor:
Jodie Chandler, Mali Camberis, Tiffany Bouchery, Mark Blaxter, Graham Le Gros, David A Eccles
Publikováno v:
F1000Research, Vol 6 (2017)
Nippostrongylus brasiliensis, a nematode parasite of rodents, has a parasitic life cycle that is an extremely useful model for the study of human hookworm infection, particularly in regards to the induced immune response. The current reference genome
Externí odkaz:
https://doaj.org/article/709fe76191a54ddebc7546b8ac96509d
Publikováno v:
Bio-Protocol, Vol 6, Iss 4 (2016)
The rodent parasite Nippostrongylus brasiliensis (N. brasiliensis) models the salient features of helminth infection including skin penetration, migration from tissues to lung, maturation and egg production in the gut. As a potent activator of system
Externí odkaz:
https://doaj.org/article/fa62e6d2e7aa44c196ba1a15581dffdc
Publikováno v:
Bio-Protocol, Vol 6, Iss 4 (2016)
Visualization of the interaction between parasitic nematodes and their host enables a better understanding of the development of the nematode during the infectious stages of its life cycle and of the effects of host response on nematode integrity in
Externí odkaz:
https://doaj.org/article/ff02efb41ed246dcb0a80af2f70ca878
Autor:
James P Hewitson, Kara J Filbey, Julia Esser-von Bieren, Mali Camberis, Christian Schwartz, Janice Murray, Lisa A Reynolds, Natalie Blair, Elaine Robertson, Yvonne Harcus, Louis Boon, Stanley Ching-Cheng Huang, Lihua Yang, Yizheng Tu, Mark J Miller, David Voehringer, Graham Le Gros, Nicola Harris, Rick M Maizels
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004676 (2015)
Over 25% of the world's population are infected with helminth parasites, the majority of which colonise the gastrointestinal tract. However, no vaccine is yet available for human use, and mechanisms of protective immunity remain unclear. In the mouse
Externí odkaz:
https://doaj.org/article/54914d01b559441e841ee0d05556fec2
Autor:
Jessica C Jang, Gang Chen, Spencer H Wang, Mark A Barnes, Josiah I Chung, Mali Camberis, Graham Le Gros, Philip J Cooper, Cathy Steel, Thomas B Nutman, Mitchell A Lazar, Meera G Nair
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004579 (2015)
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate in
Externí odkaz:
https://doaj.org/article/f414162c63a541f0b9c81b17912306a4