Iron Deficiency Anemia at Time of Vaccination Predicts Decreased Vaccine Response and Iron Supplementation at Time of Vaccination Increases Humoral Vaccine Response: A Birth Cohort Study and a Randomized Trial Follow-Up Study in Kenyan Infants

Autor: Stoffel, NU, Uyoga, MA, Mutuku, FM, Frost, JN, Mwasi, E, Paganini, D, van der Klis, FRM, Malhotra, IJ, LaBeaud, AD, Ricci, C, Karanja, S, Drakesmith, H, King, CH, Zimmermann, MB

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, 11

Background: Iron deficiency may impair adaptive immunity and is common among African infants at time of vaccination. Whether iron deficiency impairs vaccine response and whether iron supplementation improves humoral vaccine response is uncertain. Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc7a7a4c41ac50609d7068dd3064fae
https://pubmed.ncbi.nlm.nih.gov/32754150

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Parasitic infections during pregnancy need not affect infant antibody responses to early vaccination against Streptococcus pneumoniae, diphtheria, or Haemophilus influenzae type B.

Autor: McKittrick ND; Division of Infectious Diseases, Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America., Malhotra IJ; Center for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America., Vu DM; Division of Infectious Diseases, Department of Pediatrics, Lucille Packard Children's Hospital at Stanford School of Medicine, Stanford, California, United States of America., Boothroyd DB; Quantitative Sciences Unit, Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America., Lee J; Quantitative Sciences Unit, Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America., Krystosik AR; Division of Infectious Diseases, Department of Pediatrics, Lucille Packard Children's Hospital at Stanford School of Medicine, Stanford, California, United States of America., Mutuku FM; Department of Environment and Health Sciences, Technical University of Mombasa, Mombasa, Kenya., King CH; Center for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America., LaBeaud AD; Division of Infectious Diseases, Department of Pediatrics, Lucille Packard Children's Hospital at Stanford School of Medicine, Stanford, California, United States of America.

Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Feb 28; Vol. 13 (2), pp. e0007172. Date of Electronic Publication: 2019 Feb 28 (Print Publication: 2019).