A randomized clinical trial of on-demand oral pre-exposure prophylaxis does not modulate lymphoid/myeloid HIV target cell density in the foreskin.

Autor: Rametse CL; Division of Immunology, Department of Pathology, University of Cape Town, South Africa., Webb EL; Medical Research Council (MRC) International Statistics and Epidemiology Group, London School of Hygiene & Tropical Medicine., Herrera C; Department of Infectious Disease, Imperial College London, London, UK., Alinde B; Division of Immunology, Department of Pathology, University of Cape Town, South Africa., Besethi A; Division of Immunology, Department of Pathology, University of Cape Town, South Africa., Motaung B; Division of Immunology, Department of Pathology, University of Cape Town, South Africa., Mbangiwa T; Division of Immunology, Department of Pathology, University of Cape Town, South Africa., Leach L; Division of Molecular Biology and Human Genetics, Biomedical Research Institute, Stellenbosch University, Cape Town, South Africa., Sebaa S; Division of Immunology, Department of Pathology, University of Cape Town, South Africa., Pillay AAP; Division of Immunology, Department of Pathology, University of Cape Town, South Africa.; University of the Witwatersrand Perinatal HIV Research Unit, Johannesburg, South Africa., Seiphetlo TB; Division of Immunology, Department of Pathology, University of Cape Town, South Africa.; University of the Witwatersrand Perinatal HIV Research Unit, Johannesburg, South Africa., Malhangu B; Division of Immunology, Department of Pathology, University of Cape Town, South Africa.; University of the Witwatersrand Perinatal HIV Research Unit, Johannesburg, South Africa., Petkov S; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Else L; Department of Pharmacology, University of Liverpool, Liverpool, UK., Mugaba S; MRC/Uganda Virus Research Institute/London School of Hygiene & Tropical Medicine Uganda Research Unit, Entebbe, Uganda., Namubiru P; MRC/Uganda Virus Research Institute/London School of Hygiene & Tropical Medicine Uganda Research Unit, Entebbe, Uganda., Odoch G; MRC/Uganda Virus Research Institute/London School of Hygiene & Tropical Medicine Uganda Research Unit, Entebbe, Uganda., Opoka D; MRC/Uganda Virus Research Institute/London School of Hygiene & Tropical Medicine Uganda Research Unit, Entebbe, Uganda., Serwanga J; MRC/Uganda Virus Research Institute/London School of Hygiene & Tropical Medicine Uganda Research Unit, Entebbe, Uganda., Ssemata AS; MRC/Uganda Virus Research Institute/London School of Hygiene & Tropical Medicine Uganda Research Unit, Entebbe, Uganda., Kaleebu P; MRC/Uganda Virus Research Institute/London School of Hygiene & Tropical Medicine Uganda Research Unit, Entebbe, Uganda., Khoo S; Department of Pharmacology, University of Liverpool, Liverpool, UK., Lebina L; University of the Witwatersrand Perinatal HIV Research Unit, Johannesburg, South Africa., Martinson N; University of the Witwatersrand Perinatal HIV Research Unit, Johannesburg, South Africa., Chiodi F; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Fox J; King's College London, London, UK., Gray CM; Division of Immunology, Department of Pathology, University of Cape Town, South Africa.; Division of Molecular Biology and Human Genetics, Biomedical Research Institute, Stellenbosch University, Cape Town, South Africa.

Publikováno v: AIDS (London, England) [AIDS] 2023 Sep 01; Vol. 37 (11), pp. 1651-1659. Date of Electronic Publication: 2023 Jun 06.