Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Malgorzata Pierzchalska"'
Publikováno v:
Pharmaceuticals, Vol 7, Iss 9, Pp 913-942 (2014)
Mitochondria are crucially important for maintaining not only the energy homeostasis, but the proper cellular functions in a general sense. Impairment of mitochondrial functions is observed in a broad variety of pathological states such as neoplastic
Externí odkaz:
https://doaj.org/article/7d2fb14299c442cea3e9d987a6a6a242
Publikováno v:
BioTechniques, Vol 52, Iss 5, Pp 307-315 (2012)
Investigating intestinal physiology in vitro remains challenging due to the lack of an effective primary enterocyte culture system. Recently developed protocols for growing organoids containing crypts and villus from adult mouse intestinal epithelium
Externí odkaz:
https://doaj.org/article/c3b0f8ea54c748dfb69dcc64aa73308c
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 12, p 2093 (2016)
Ketogenesis and ketolysis are central metabolic processes activated during the response to fasting. Ketogenesis is regulated in multiple stages, and a nuclear receptor peroxisome proliferator activated receptor α (PPARα) is one of the key transcrip
Externí odkaz:
https://doaj.org/article/0ea07dae22214ae5becd64db7c255805
Autor:
Magdalena Podlacha, Lidia Gaffke, Łukasz Grabowski, Jagoda Mantej, Michał Grabski, Małgorzata Pierzchalska, Karolina Pierzynowska, Grzegorz Węgrzyn, Alicja Węgrzyn
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract One of the hopes for overcoming the antibiotic resistance crisis is the use of bacteriophages to combat bacterial infections, the so-called phage therapy. This therapeutic approach is generally believed to be safe for humans and animals as p
Externí odkaz:
https://doaj.org/article/df9c80bb398e4f7098d62910ccb6774c
Publikováno v:
International Journal of Molecular Sciences. 23:14156
Peroxisome proliferator-activated receptor alpha ($PPAR\alpha$) is expressed throughout the mammalian gut: in epithelial cells, in the villi of enterocytes and in Paneth cells of intestinal crypts, as well as in some immune cells (e.g., lamina propri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d645743617520b65ac840c646025e71
https://doi.org/10.3390/ijms232214156
https://doi.org/10.3390/ijms232214156
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 10545, p 10545 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 10545, p 10545 (2021)
Peroxisome proliferator-activated receptor α is a potent regulator of systemic and cellular metabolism and energy homeostasis, but it also suppresses various inflammatory reactions. In this review, we focus on its role in the regulation of innate im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deff493121bbf5f599b70bdf079d565c
https://pubmed.ncbi.nlm.nih.gov/34638886
https://pubmed.ncbi.nlm.nih.gov/34638886
Autor:
Maja Grabacka, Jana Lakatošová, Gabriela Waś, Anna Wydra, Karolina Jakubiec, Veronika Fialková, Ivana Speváková, Małgorzata Pierzchalska
Publikováno v:
Applied Sciences, Vol 14, Iss 17, p 7992 (2024)
The aim of this study was to evaluate the impact of ethanol extracts from sea buckthorn and Cornelian cherry fruits and leaves on physiology of gastrointestinal tract cells. We used three cell lines relevant to the types of cells, which are exposed t
Externí odkaz:
https://doaj.org/article/5a585454ca494fd3b19d0caefccbe181
Publikováno v:
Protoplasma
The method of organoid culture has become a tool widely used in gastrointestinal research, but so far, the migration of organoids derived from gut epithelium and formed in 3D Matrigel matrix has not been reported and studied. The intestinal epithelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729acf33eea67efa8de3a04a63b45628
http://europepmc.org/articles/PMC6514079
http://europepmc.org/articles/PMC6514079
Publikováno v:
Cytotechnology
Recently organoids have become widely used in vitro models of many tissue and organs. These type of structures, originated from embryonic or adult mammalian intestines, are called "mini guts". They organize spontaneously when intestinal crypts or ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da400a8a95f4506ab0318ce9eb36045e
https://doi.org/10.1007/s10616-018-0194-8
https://doi.org/10.1007/s10616-018-0194-8
Autor:
Malgorzata Czyrnek, Anna Gielicz, Malgorzata Pierzchalska, Maja Grabacka, Malgorzata Panek, Barbara Mickowska
Publikováno v:
Comparative Immunology, Microbiology and Infectious Diseases. 53:7-18
The intestinal epithelial cells reside in close proximity to myofibroblasts and microbiota, which are supposed to have an impact on intestinal stem cells fate and to influence processes of tissue maturation and regeneration. Mechanism underlying thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5633764cb4dcbf24020c6f55af43ae8
https://doi.org/10.1016/j.cimid.2017.06.002
https://doi.org/10.1016/j.cimid.2017.06.002