Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Malgorzata Pienkowska"'
Autor:
David Malkin, Richard J. Gilbertson, David W. Ellison, Uri Tabori, Michael D. Taylor, Cynthia Hawkins, Eric Bouffet, Rosanna Weksberg, Jonathan L. Finlay, Nada Jabado, Maria Isabel Achatz, Stefan M. Pfister, Rishi Lulla, Eugene I. Hwang, Brent T. Harris, Myran Ben-Arush, Rina Dvir, Sanaa Choufani, Ana Novokmet, Ruth Tatevossian, David Shih, Vijay Ramaswamy, Stephen Mack, Malgorzata Pienkowska, Anita Villani, Adam Shlien, Diana M. Merino
Appendix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eaefeb9be99647fd51217c8ee4e4797
https://doi.org/10.1158/1078-0432.22454475
https://doi.org/10.1158/1078-0432.22454475
Autor:
David Malkin, Richard J. Gilbertson, David W. Ellison, Uri Tabori, Michael D. Taylor, Cynthia Hawkins, Eric Bouffet, Rosanna Weksberg, Jonathan L. Finlay, Nada Jabado, Maria Isabel Achatz, Stefan M. Pfister, Rishi Lulla, Eugene I. Hwang, Brent T. Harris, Myran Ben-Arush, Rina Dvir, Sanaa Choufani, Ana Novokmet, Ruth Tatevossian, David Shih, Vijay Ramaswamy, Stephen Mack, Malgorzata Pienkowska, Anita Villani, Adam Shlien, Diana M. Merino
Figure S1. Sample flow-chart describing the number of biological samples and clinical data obtained through an international multi-institutional effort and the distribution of samples in each microarray
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361d41fd9453dbfadfe788305a9f4f51
https://doi.org/10.1158/1078-0432.22454472
https://doi.org/10.1158/1078-0432.22454472
Autor:
David Malkin, Richard J. Gilbertson, David W. Ellison, Uri Tabori, Michael D. Taylor, Cynthia Hawkins, Eric Bouffet, Rosanna Weksberg, Jonathan L. Finlay, Nada Jabado, Maria Isabel Achatz, Stefan M. Pfister, Rishi Lulla, Eugene I. Hwang, Brent T. Harris, Myran Ben-Arush, Rina Dvir, Sanaa Choufani, Ana Novokmet, Ruth Tatevossian, David Shih, Vijay Ramaswamy, Stephen Mack, Malgorzata Pienkowska, Anita Villani, Adam Shlien, Diana M. Merino
Figure S3. Ploidy values obtained from allele-specific copy number analysis are depicted. Scatter plot of CPCs (red), CPPs (yellow) and aCPPs (light blue) showing two distinct groups in CPCs: hypodiploid CPCs (dark blue), and hyperdiploid CPCs (green
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb21c8af1a58661282bb52862b6e227
https://doi.org/10.1158/1078-0432.22454466.v1
https://doi.org/10.1158/1078-0432.22454466.v1
Autor:
David Malkin, Richard J. Gilbertson, David W. Ellison, Uri Tabori, Michael D. Taylor, Cynthia Hawkins, Eric Bouffet, Rosanna Weksberg, Jonathan L. Finlay, Nada Jabado, Maria Isabel Achatz, Stefan M. Pfister, Rishi Lulla, Eugene I. Hwang, Brent T. Harris, Myran Ben-Arush, Rina Dvir, Sanaa Choufani, Ana Novokmet, Ruth Tatevossian, David Shih, Vijay Ramaswamy, Stephen Mack, Malgorzata Pienkowska, Anita Villani, Adam Shlien, Diana M. Merino
Figure S2. Unsupervised clustering analysis of CPTs showed significant segregation of CPCs from CPPs with aCPPs (subgroups delineated by red rectangles p=0·05). Clustering was performed using PVCLUST and 1000 gene expression normalized intensities a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbc47a9dbafb62b8ea5588030dfa9ed
https://doi.org/10.1158/1078-0432.22454469.v1
https://doi.org/10.1158/1078-0432.22454469.v1
Autor:
David Malkin, Richard J. Gilbertson, David W. Ellison, Uri Tabori, Michael D. Taylor, Cynthia Hawkins, Eric Bouffet, Rosanna Weksberg, Jonathan L. Finlay, Nada Jabado, Maria Isabel Achatz, Stefan M. Pfister, Rishi Lulla, Eugene I. Hwang, Brent T. Harris, Myran Ben-Arush, Rina Dvir, Sanaa Choufani, Ana Novokmet, Ruth Tatevossian, David Shih, Vijay Ramaswamy, Stephen Mack, Malgorzata Pienkowska, Anita Villani, Adam Shlien, Diana M. Merino
Table S1-S3. S1Choroid plexus tumor chromosomal instability reported in literature S2-Characterization of patient and sample cohort used in analysis S3 Frequency of TP53 mutations in CPTs and characterization of mutation types. Abbreviations: CPC: ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470736b7aa512aedc5e32196be62de3e
https://doi.org/10.1158/1078-0432.22454457.v1
https://doi.org/10.1158/1078-0432.22454457.v1
Autor:
David Malkin, Richard J. Gilbertson, David W. Ellison, Uri Tabori, Michael D. Taylor, Cynthia Hawkins, Eric Bouffet, Rosanna Weksberg, Jonathan L. Finlay, Nada Jabado, Maria Isabel Achatz, Stefan M. Pfister, Rishi Lulla, Eugene I. Hwang, Brent T. Harris, Myran Ben-Arush, Rina Dvir, Sanaa Choufani, Ana Novokmet, Ruth Tatevossian, David Shih, Vijay Ramaswamy, Stephen Mack, Malgorzata Pienkowska, Anita Villani, Adam Shlien, Diana M. Merino
supplemental figure and table legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98839dd03b336ec1604dbd0c6a19ca2e
https://doi.org/10.1158/1078-0432.22454454
https://doi.org/10.1158/1078-0432.22454454
Autor:
David Malkin, Richard J. Gilbertson, David W. Ellison, Uri Tabori, Michael D. Taylor, Cynthia Hawkins, Eric Bouffet, Rosanna Weksberg, Jonathan L. Finlay, Nada Jabado, Maria Isabel Achatz, Stefan M. Pfister, Rishi Lulla, Eugene I. Hwang, Brent T. Harris, Myran Ben-Arush, Rina Dvir, Sanaa Choufani, Ana Novokmet, Ruth Tatevossian, David Shih, Vijay Ramaswamy, Stephen Mack, Malgorzata Pienkowska, Anita Villani, Adam Shlien, Diana M. Merino
Purpose: To investigate molecular alterations in choroid plexus tumors (CPT) using a genome-wide high-throughput approach to identify diagnostic and prognostic signatures that will refine tumor stratification and guide therapeutic options.Experimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46808d524dc0c4971da64085381d95ab
https://doi.org/10.1158/1078-0432.c.6522753
https://doi.org/10.1158/1078-0432.c.6522753
Autor:
David Malkin, Richard J. Gilbertson, David W. Ellison, Uri Tabori, Michael D. Taylor, Cynthia Hawkins, Eric Bouffet, Rosanna Weksberg, Jonathan L. Finlay, Nada Jabado, Maria Isabel Achatz, Stefan M. Pfister, Rishi Lulla, Eugene I. Hwang, Brent T. Harris, Myran Ben-Arush, Rina Dvir, Sanaa Choufani, Ana Novokmet, Ruth Tatevossian, David Shih, Vijay Ramaswamy, Stephen Mack, Malgorzata Pienkowska, Anita Villani, Adam Shlien, Diana M. Merino
Figure S5. Kaplan-Meier curves depicting (A) overall survival and (B) event-free survival estimates of CPCs by ploidy (hyperdiploid: green, hypodiploid: blue). Statistical values were obtained with the Log-rank (Mantel-Cox) test.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16412ad7ba14a698bbd383d5edb5f3a2
https://doi.org/10.1158/1078-0432.22454460.v1
https://doi.org/10.1158/1078-0432.22454460.v1
Autor:
David Malkin, Richard J. Gilbertson, David W. Ellison, Uri Tabori, Michael D. Taylor, Cynthia Hawkins, Eric Bouffet, Rosanna Weksberg, Jonathan L. Finlay, Nada Jabado, Maria Isabel Achatz, Stefan M. Pfister, Rishi Lulla, Eugene I. Hwang, Brent T. Harris, Myran Ben-Arush, Rina Dvir, Sanaa Choufani, Ana Novokmet, Ruth Tatevossian, David Shih, Vijay Ramaswamy, Stephen Mack, Malgorzata Pienkowska, Anita Villani, Adam Shlien, Diana M. Merino
Figure S4. Gene set enrichment analysis (GSEA) comparing the expression of different biological pathways and processes between hypodiploid (red) and hyperdiploid (blue) CPCs. (5% FDR, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de02edb244db8c8c3802d14b69828fc
https://doi.org/10.1158/1078-0432.22454463
https://doi.org/10.1158/1078-0432.22454463
Autor:
Cynthia Hawkins, Christian Thomas, Diana M. Merino, Michael Brudno, Eric Bouffet, Tanya Guha, David Malkin, Adam Shlien, Jonathan L. Finlay, Sanaa Choufani, Rosanna Weksberg, Martin Sill, Richard J. Gilbertson, Martin Hasselblatt, David Capper, Andrei L. Turinsky, Uri Tabori, Nada Jabado, Malgorzata Pienkowska, Ana Novokmet
Publikováno v:
Clinical Epigenetics
Histological grading of choroid plexus tumors (CPTs) remains the best prognostic tool to distinguish between aggressive choroid plexus carcinoma (CPC) and the more benign choroid plexus papilloma (CPP) or atypical choroid plexus papilloma (aCPP); how