Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Malgorzata Nocula-Lugowska"'
Autor:
Xiaotian Zhong, Jennifer Schenk, Paul Sakorafas, John Chamberland, Amy Tam, L. Michael Thomas, Grace Yan, Aaron M. D’ Antona, Laura Lin, Malgorzata Nocula-Lugowska, Yan Zhang, Eric Sousa, Justin Cohen, Ling Gu, Molica Abel, Jacob Donahue, Sean Lim, Caryl Meade, Jing Zhou, Logan Riegel, Alex Birch, Brian J. Fennell, Edward Franklin, Jose M. Gomes, Boriana Tzvetkova, John J. Scarcelli
Publikováno v:
Journal of Biotechnology. 360:79-91
This study has employed mammalian transient expression systems to generate afucosylated antibodies and antibody Fc mutants for rapid candidate screening in discovery and early development. While chemical treatment with the fucose analogue 2-fluoro-pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a3270f0ecbe896963fd255d3531385
https://doi.org/10.1016/j.jbiotec.2022.10.016
https://doi.org/10.1016/j.jbiotec.2022.10.016
Autor:
Magnus Malmqvist, Shahir S. Rizk, Anthony A. Kossiakoff, Somnath Mukherjee, Sangwoo S. Kim, Malgorzata Nocula-Lugowska, Dionne H. Griffin, James R. Horn
Conformational changes in proteins due to ligand binding are ubiquitous in biological processes and are integral to many biological systems. However, it is often challenging to link ligand-induced conformational changes to a resulting biological func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b141ceaec5b639a5c3ba985b09e3e8f
https://europepmc.org/articles/PMC5827440/
https://europepmc.org/articles/PMC5827440/
Publikováno v:
Journal of Molecular Biology. 427:2532-2547
Focal adhesion protein paxillin links integrin and growth factor signaling to actin cytoskeleton. Most of paxillin signaling activity is regulated via leucine-rich LD motifs (LD1-LD5) located at the N-terminus. Here, we demonstrate a method to engine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de9fc9fad617c89d63d3da5090a39068
https://doi.org/10.1016/j.jmb.2015.06.004
https://doi.org/10.1016/j.jmb.2015.06.004